97 Matching Annotations
  1. Aug 2024
  2. www.pnas.org www.pnas.org
    Highly specific σ<sub>2</sub>R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response
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    1. scibot 13 Aug 2024
      Cell Signaling #3177

      DOI: 10.1073/pnas.2306090120

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    pnas.org/doi/10.1073/pnas.2306090120
  3. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
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    1. scibot 02 Aug 2024
      3177

      DOI: 10.1186/s13578-021-00640-2

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    cellandbioscience.biomedcentral.com/article/10.1186/s13578-021-00640-2
  4. Jul 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
    1
    1. scibot 23 Jul 2024
      AB_2119845

      DOI: 10.1016/j.celrep.2024.114402

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    sciencedirect.com/science/article/pii/S2211124724007307
  6. www.cell.com www.cell.com
    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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    1. scibot 12 Jul 2024
      RRID:AB_2119845

      DOI: 10.1016/j.devcel.2024.06.005

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    cell.com/developmental-cell/fulltext/S1534-5807(24)00382-4
  7. Jun 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER
    1
    1. scibot 21 Jun 2024
      RRID:AB_2119845

      DOI: 10.1016/j.celrep.2024.114358

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    sciencedirect.com/science/article/pii/S2211124724006867
  9. www.sciencedirect.com www.sciencedirect.com
    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
    1
    1. scibot 21 Jun 2024
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2024.110196

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    sciencedirect.com/science/article/pii/S2589004224014214
  10. May 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER-stress in mouse serotonin neurons triggers a depressive phenotype alleviated by ketamine targeting eIF2α signaling
    1
    1. scibot 09 May 2024
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2024.109787

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    ncbi.nlm.nih.gov/pmc/articles/PMC11070602/
  12. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
    1
    1. scibot 08 May 2024
      RRID:AB_2119845

      DOI: 10.1016/j.cmet.2024.04.014

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    sciencedirect.com/science/article/pii/S1550413124001347
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 May 2024
      RRID:AB_2119845

      DOI: 10.1111/bph.16391

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16391
  14. Apr 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
    1
    1. scibot 28 Apr 2024
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2024.109672

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039351/
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Caffeic acid does not protect human pancreatic β cells against stearic acid-induced ER stress and apoptosis
    1
    1. scibot 25 Apr 2024
      RRID:AB_2119845

      DOI: 10.1002/ejlt.202300206

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    onlinelibrary.wiley.com/doi/full/10.1002/ejlt.202300206
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis
    1
    1. scibot 25 Apr 2024
      RRID:AB_2119845

      DOI: 10.1111/jnc.16114

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16114
  18. Mar 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Brucella-driven host N-glycome remodeling controls infection
    2
    1. scibot 29 Mar 2024
      RRID:AB_2119845

      DOI: 10.1016/j.chom.2024.03.003

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    2. scibot 29 Mar 2024
      RRID:AB_2119845

      DOI: 10.1016/j.chom.2024.03.003

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    sciencedirect.com/science/article/pii/S1931312824000830
  20. Feb 2024
  21. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
    1
    1. scibot 22 Feb 2024
      RRID:AB_21

      DOI: 10.1101/2023.10.02.560521

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    52.53.155.43/4a182fdd92d1ce35b13f136f7657c6c9ec6a6224/2023.10.02.560521v1.full-html.html
  22. Dec 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TXNDC12 inhibits lipid peroxidation and ferroptosis
    1
    1. scibot 06 Dec 2023
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2023.108393

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690572/
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
    1
    1. scibot 17 Nov 2023
      RRID:AB_2119845

      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  26. www.sciencedirect.com www.sciencedirect.com
    Exploring the role of SWI/SNF complex subunit BAF60c in lipid metabolism and inflammation in fish
    1
    1. scibot 04 Nov 2023
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2023.108207

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    sciencedirect.com/science/article/pii/S2589004223022848
  27. Oct 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
    1
    1. scibot 27 Oct 2023
      RRID:AB_2119845

      DOI: 10.1016/j.celrep.2023.113318

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    sciencedirect.com/science/article/pii/S221112472301330X
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LINE-1 activation in the cerebellum drives ataxia
    1
    1. scibot 20 Oct 2023
      RRID:AB_2119845

      DOI: 10.1016/j.neuron.2022.08.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC9588660/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
    1
    1. scibot 05 Oct 2023
      RRID:AB_2119845

      DOI: 10.7554/eLife.85898

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541180/
  31. Sep 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
    1
    1. scibot 17 Sep 2023
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2023.107731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10494175/
  33. www.sciencedirect.com www.sciencedirect.com
    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
    1
    1. scibot 07 Sep 2023
      RRID:AB_2119845

      DOI: 10.1016/j.celrep.2023.113070

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    sciencedirect.com/science/article/pii/S2211124723010811
  34. Aug 2023
  35. www.sciencedirect.com www.sciencedirect.com
    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
    1
    1. scibot 18 Aug 2023
      RRID:AB_2119845

      DOI: 10.1016/j.celrep.2023.112986

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    sciencedirect.com/science/article/pii/S221112472300997X
  36. Jun 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
    1
    1. scibot 29 Jun 2023
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2023.107113

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    sciencedirect.com/science/article/pii/S2589004223011902
  38. May 2023
  39. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
    1
    1. scibot 12 May 2023
      RRID:AB_2119845

      DOI: 10.1210/endocr/bqad035

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    academic.oup.com/endo/article/164/4/bqad035/7056674
  40. www.nature.com www.nature.com
    SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
    1
    1. scibot 05 May 2023
      RRID:AB_2119845

      DOI: 10.1038/s41467-022-31566-z

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    nature.com/articles/s41467-022-31566-z
  41. Apr 2023
  42. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
    1
    1. scibot 20 Apr 2023
      RRID:AB_2119845

      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  43. Mar 2023
  44. journals.lww.com journals.lww.com
    TUG-891 inhibits neuronal endoplasmic reticulum stress and... : Neural Regeneration Research
    1
    1. scibot 30 Mar 2023
      RRID:AB_2119845

      DOI: 10.4103/1673-5374.369116

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    journals.lww.com/nrronline/Fulltext/2023/10000/TUG_891_inhibits_neuronal_endoplasmic_reticulum.34.aspx
  45. Feb 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
    1
    1. scibot 11 Feb 2023
      RRID:AB_2119845

      DOI: 10.1016/j.isci.2023.105965

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    sciencedirect.com/science/article/pii/S2589004223000421
  47. www.sciencedirect.com www.sciencedirect.com
    MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112066

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    sciencedirect.com/science/article/pii/S2211124723000773
  48. Jan 2023
  49. journals.lww.com journals.lww.com
    Valproate reduces retinal ganglion cell apoptosis in rats... : Neural Regeneration Research
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    1. scibot 19 Jan 2023
      RRID:AB_2119845

      DOI: 10.4103/1673-5374.357913

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    journals.lww.com/nrronline/Fulltext/2023/07000/Valproate_reduces_retinal_ganglion_cell_apoptosis.37.aspx
  50. Dec 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.isci.2022.105626

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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  52. www.sciencedirect.com www.sciencedirect.com
    A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
    1
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      DOI: 10.1016/j.ebiom.2022.104379

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    sciencedirect.com/science/article/pii/S2352396422005618
  53. Nov 2022
  54. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
    1
    1. scibot 22 Nov 2022
      AB_2119845

      DOI: 10.3390/cells11223665

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    mdpi.com/2073-4409/11/22/3665
  55. Sep 2022
  56. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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      DOI: 10.1016/j.celrep.2022.111415

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    sciencedirect.com/science/article/pii/S2211124722012566
  57. www.sciencedirect.com www.sciencedirect.com
    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
    1
    1. scibot 24 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.016

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    sciencedirect.com/science/article/pii/S1535610822003804
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endoplasmic reticulum stress induces Alzheimer's disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein
    1
    1. scibot 17 Sep 2022
      RRID:AB_2119845

      DOI: 10.1111/jnc.15687

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15687
  59. Jun 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Age-related endoplasmic reticulum stress represses testosterone synthesis via attenuation of the circadian clock in Leydig cells
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      AB_2119845

      DOI: 10.1016/j.theriogenology.2022.06.010

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    sciencedirect.com/science/article/pii/S0093691X22002357
  61. Apr 2022
  62. www.sciencedirect.com www.sciencedirect.com
    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
    1
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    Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology
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    6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels
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    Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes
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  124. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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    TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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  128. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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    Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death
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    Systematic Characterization of Stress-Induced RNA Granulation
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    CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
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    Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity
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