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14 Matching Annotations

Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BRAF Inhibition–Associated Nuclear Remodeling is Linked to Cancer-Associated Fibroblast Activation

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1. scibot 18 Jul 2026
  
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  RRID:AB_2121046
  
  DOI: 10.1158/2767-9764.CRC-25-0682
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13373777/
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combined Inhibition of HRAS and MEK Induces Tumor Regression and Restores Myogenic Differentiation in HRAS-Mutant Rhabdomyosarcoma

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1. scibot 19 May 2026
  
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  RRID:AB_2121046
  
  DOI: 10.1158/0008-5472.CAN-25-2985
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13176821/
www.sciencedirect.com www.sciencedirect.com

Accumulated sotorasib-bound KRASG12C reactivates the MAPK pathway and drives sotorasib resistance via the DHX9-RAC1-PAK1 axis

1
1. scibot 06 May 2026
  
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  RRID:AB_2121046
  
  DOI: 10.1016/j.celrep.2026.117338
  
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sciencedirect.com/science/article/pii/S221112472600416X
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma

1
1. scibot 24 Apr 2026
  
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  RRID:AB_2121046
  
  DOI: 10.1016/j.ccell.2026.03.020
  
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sciencedirect.com/science/article/pii/S1535610826001741
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IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes

1
1. scibot 02 Apr 2026
  
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  RRID:AB_2121046
  
  DOI: 10.1016/j.chembiol.2026.03.005
  
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sciencedirect.com/science/article/pii/S2451945626000759
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers

1
1. scibot 18 Mar 2026
  
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  RRID:AB_2121046
  
  DOI: 10.1126/scisignal.adx5186
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12983336/
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RAS mutation–specific responses to paralog- and state-selective RAS inhibitors

1
1. scibot 20 Dec 2025
  
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  RRID:AB_2121046
  
  DOI: 10.1158/1541-7786.MCR-25-0319
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
Aug 2024
www.sciencedirect.com www.sciencedirect.com

H-Ras induces exuberant de novo dendritic protrusion growth in mature neurons regardless of cell type

1
1. scibot 20 Aug 2024
  
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  AB_2121046
  
  DOI: 10.1016/j.isci.2024.110535
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
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sciencedirect.com/science/article/pii/S2589004224017607
May 2024
www.cell.com www.cell.com

Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders

1
1. scibot 10 May 2024
  
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  RRID:AB_2121046
  
  DOI: 10.1016/j.isci.2024.109802
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
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cell.com/iscience/abstract/S2589-0042(24)01024-1
Feb 2024
52.53.155.43 52.53.155.43

RAS isoform specific activities are disrupted by disease associated mutations during cell differentiation

1
1. scibot 22 Feb 2024
  
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  RRID:AB_2121046
  
  DOI: 10.1101/2023.10.05.561021
  
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52.53.155.43/19126de606c776a10e00c0c9a385ef3636eaaf16/2023.10.05.561021v2.full (1)-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Oncogenic Transformation Drives DNA Methylation Loss and Transcriptional Activation of Transposable Element Loci

1
1. scibot 02 Feb 2024
  
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  RRID:AB_2121046
  
  DOI: 10.1158/0008-5472.CAN-22-3485
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10527578/
Sep 2023
52.53.155.43 52.53.155.43

2584-html.html

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1. scibot 22 Sep 2023
  
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  RRID:AB_2121046
  
  DOI: 10.1158/0008-5472.CAN-22-3485
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
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52.53.155.43/b320dae4ebc2856ca2e3b35d653595100514acab/2584-html.html
Sep 2021
www.sciencedirect.com www.sciencedirect.com

KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

1
1. scibot 22 Sep 2021
  
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  RRID:AB_2121046
  
  DOI: 10.1016/j.molcel.2021.09.001
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
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  SciCrunch record: RRID:AB_2121046
  
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sciencedirect.com/science/article/pii/S1097276521007358
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System

1
1. scibot 03 Sep 2020
  
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  RRID:AB_2121046
  
  DOI: 10.1016/j.chembiol.2020.06.012
  
  Resource: (Proteintech Cat# 18295-1-AP, RRID:AB_2121046)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2121046
  
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  RRIDCUR:Validated RRID:AB_2121046
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RRIDCUR:Validated

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pubmed.ncbi.nlm.nih.gov/32668202/