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Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ducts

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Nov 2025
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Insulin-Like Growth Factor 1 Receptor Regulates Breast Cancer Cell Adhesion through Beta-1 Integrin

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Oct 2025
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1-s2.0-S2589004225019431-main-html.html

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Mar 2025
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PDF-html.html

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1. scibot 25 Mar 2025
  
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YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1-mediated reprogramming of bone mesenchymal stem cells

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biosignaling.biomedcentral.com biosignaling.biomedcentral.com

Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas

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biosignaling.biomedcentral.com/articles/10.1186/s12964-025-02115-0
Oct 2024
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Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling

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aacrjournals.org/mcr/article/19/1/61/271645/Metformin-Mitigates-DPP-4-Inhibitor-Induced-Breast
Sep 2024
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Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity

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1. scibot 25 Sep 2024
  
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Jan 2024
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RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling

3
1. scibot 20 Jan 2024
  
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  DOI: 10.1126/scisignal.adg5289
  
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science.org/doi/10.1126/scisignal.adg5289
Nov 2023
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HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B

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Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer’s disease

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113392
  
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Insulin receptor loss impairs mammary tumorigenesis in mice

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Oct 2023
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Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer

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  DOI: 10.1158/0008-5472.CAN-22-3484
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10543968/
Aug 2023
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IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy

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  DOI: 10.1016/j.celrep.2023.112889
  
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Jul 2023
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Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations

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  DOI: 10.1016/j.celrep.2023.112840
  
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IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression

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1. scibot 06 Jul 2023
  
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  DOI: 10.1158/1535-7163.MCT-22-0147
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
Jun 2023
52.53.155.43 52.53.155.43

can-22-3484-html.html

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52.53.155.43/78582fc87eae4b7ad3ee30a95dff40dcb4611547/can-22-3484-html.html
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

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  DOI: 10.1158/1541-7786.MCR-22-0090
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
Feb 2023
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Stress Granules determine the Development of Obesity-associated Pancreatic Cancer

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ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
Jan 2023
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Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice

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Dec 2022
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The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC

1
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Nov 2022
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Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier

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1. scibot 22 Nov 2022
  
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  DOI: 10.1016/j.crmeth.2022.100338
  
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Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect

1
1. scibot 04 Nov 2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9627217/
Sep 2022
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The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling

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  DOI: 10.1016/j.jbc.2022.102532
  
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sciencedirect.com/science/article/pii/S0021925822009759
May 2022
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Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment

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  DOI: 10.1186/s40478-022-01352-5
  
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Mar 2022
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Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells

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  DOI: 10.1016/j.celrep.2022.110548
  
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Jan 2022
52.53.155.43 52.53.155.43

en.2019-00132-html.html

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  DOI: 10.1210/en.2019-00132
  
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Dec 2021
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Translational and post-translational control of human naïve versus primed pluripotency

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  DOI: 10.1016/j.isci.2021.103645
  
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sciencedirect.com/science/article/pii/S2589004221016151
Aug 2021
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Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

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1. scibot 14 Aug 2021
  
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  DOI: 10.1210/en.2019-00177
  
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academic.oup.com/endo/article/160/11/2692/5551999
Jul 2021
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Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation

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1. scibot 29 Jul 2021
  
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  DOI: 10.1210/en.2018-00099
  
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academic.oup.com/endo/article/159/4/1774/4850601
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Untitled document

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  DOI: 10.1210/en.2018-00899
  
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academic.oup.com/endo/article/160/2/377/5235619
Feb 2021
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An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108744
  
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Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes

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1. scibot 10 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108729
  
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Insulin-Like Growth Factor-1 Inhibits Spreading Depression-Induced Trigeminal Calcitonin Gene Related Peptide, Oxidative Stress & Neuronal Activation in Rat

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  AB_2122378
  
  DOI: 10.1016/j.brainres.2020.146673
  
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Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling

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  DOI: 10.1016/j.celrep.2020.108007
  
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Disc1 Carrier Mice Exhibit Alterations in Neural pIGF-1Rβ and Related Kinase Expression

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  Rabbit anti-IGF1-Rβ
  
  DOI: 10.3389/fncel.2020.00094
  
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IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway

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  rabbit anti-IGF-1R
  
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Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment

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  DOI: 10.1016/j.yexcr.2018.11.006
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.04.034
  
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Untitled document

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  DOI: 10.1210/en.2019-00132
  
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  DOI: 10.1016/j.celrep.2019.02.081
  
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  DOI: 10.1016/j.cell.2019.02.030
  
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Nov 2018
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Untitled document

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation

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  AB_2122378
  
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Nov 2017
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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model

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  AB_2122378
  
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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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  AB_2122378
  
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Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

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  AB_2122378
  
  Curator: @kaitlinsung
  
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