47 Matching Annotations
  1. Oct 2024
  2. aacrjournals.org aacrjournals.org
    Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling
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    1. scibot 02 Oct 2024
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      DOI: 10.1158/1541-7786.MCR-20-0115

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    aacrjournals.org/mcr/article/19/1/61/271645/Metformin-Mitigates-DPP-4-Inhibitor-Induced-Breast
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
    1
    1. scibot 25 Sep 2024
      AB_2122378

      DOI: 10.1016/j.celrep.2024.114762

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    sciencedirect.com/science/article/pii/S2211124724011136
  5. Jan 2024
  6. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    3
    1. scibot 20 Jan 2024
      RRID:AB_2122378

      DOI: 10.1126/scisignal.adg5289

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    2. scibot 12 Jan 2024
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      DOI: 10.1126/scisignal.adg5289

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    3. scibot 12 Jan 2024
      RRID:AB_2122378

      DOI: 10.1126/scisignal.adg5289

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    science.org/doi/10.1126/scisignal.adg5289
  7. Nov 2023
  8. www.sciencedirect.com www.sciencedirect.com
    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.xcrm.2023.101285

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    sciencedirect.com/science/article/pii/S2666379123004792
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    Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer’s disease
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    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113392

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    sciencedirect.com/science/article/pii/S2211124723014043
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    Insulin receptor loss impairs mammary tumorigenesis in mice
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    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113251

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    sciencedirect.com/science/article/pii/S2211124723012639
  11. Oct 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer
    1
    1. scibot 06 Oct 2023
      RRID:AB_2122378

      DOI: 10.1158/0008-5472.CAN-22-3484

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  13. Aug 2023
  14. www.sciencedirect.com www.sciencedirect.com
    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
    1
    1. scibot 03 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112889

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    sciencedirect.com/science/article/pii/S2211124723009002
  15. Jul 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations
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    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112840

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    sciencedirect.com/science/article/pii/S2211124723008513
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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    1. scibot 06 Jul 2023
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      DOI: 10.1158/1535-7163.MCT-22-0147

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  18. Jun 2023
  19. 52.53.155.43 52.53.155.43
    can-22-3484-html.html
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    1. scibot 01 Jun 2023
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      DOI: 10.1158/0008-5472.can-22-3484

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  20. Mar 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
    2
    1. scibot 05 Mar 2023
      RRID: AB_2122378

      DOI: 10.1158/1541-7786.MCR-22-0090

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    2. scibot 05 Mar 2023
      RRID:AB_2122378

      DOI: 10.1158/1541-7786.MCR-22-0090

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  22. Feb 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
    1
    1. scibot 09 Feb 2023
      RRID:AB_2122378

      DOI: 10.1158/2159-8290.CD-21-1672

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  24. Jan 2023
  25. academic.oup.com academic.oup.com
    Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice
    1
    1. scibot 21 Jan 2023
      AB_2122378

      DOI: 10.1210/endocr/bqac214

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    academic.oup.com/endo/article/164/3/bqac214/6969391
  26. Dec 2022
  27. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111759

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    sciencedirect.com/science/article/pii/S2211124722016424
  28. Nov 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.crmeth.2022.100338

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    sciencedirect.com/science/article/pii/S2667237522002351
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect
    1
    1. scibot 04 Nov 2022
      AB_2122378

      DOI: 10.3389/fendo.2022.951928

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    ncbi.nlm.nih.gov/pmc/articles/PMC9627217/
  31. Sep 2022
  32. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
    1
    1. scibot 27 Sep 2022
      RRID:AB_2122378

      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
  33. May 2022
  34. link.springer.com link.springer.com
    Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment
    1
    1. scibot 06 May 2022
      RRID:AB_2122378

      DOI: 10.1186/s40478-022-01352-5

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    link.springer.com/article/10.1186/s40478-022-01352-5
  35. Mar 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
    1
    1. scibot 23 Mar 2022
      RRID:AB_2122378

      DOI: 10.1016/j.celrep.2022.110548

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    sciencedirect.com/science/article/pii/S2211124722002893
  37. Jan 2022
  38. 52.53.155.43 52.53.155.43
    en.2019-00132-html.html
    1
    1. scibot 13 Jan 2022
      AB_2122378

      DOI: 10.1210/en.2019-00132

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    52.53.155.43/557660d1c11b27494adc93fd56191c3d11e841d6/en.2019-00132-html.html
  39. Dec 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Translational and post-translational control of human naïve versus primed pluripotency
    1
    1. scibot 30 Dec 2021
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      DOI: 10.1016/j.isci.2021.103645

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    sciencedirect.com/science/article/pii/S2589004221016151
  41. Aug 2021
  42. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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    1. scibot 14 Aug 2021
      RRID:AB_2122378

      DOI: 10.1210/en.2019-00177

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    academic.oup.com/endo/article/160/11/2692/5551999
  43. Jul 2021
  44. academic.oup.com academic.oup.com
    Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation
    1
    1. scibot 29 Jul 2021
      AB_2122378

      DOI: 10.1210/en.2018-00099

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    academic.oup.com/endo/article/159/4/1774/4850601
  45. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 27 Jul 2021
      RRID:AB_2122378

      DOI: 10.1210/en.2018-00899

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    academic.oup.com/endo/article/160/2/377/5235619
  46. Feb 2021
  47. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
    1
    1. scibot 24 Feb 2021
      RRID:AB_2122378

      DOI: 10.1016/j.celrep.2021.108744

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    sciencedirect.com/science/article/pii/S2211124721000577
  48. www.sciencedirect.com www.sciencedirect.com
    Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes
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    1. scibot 10 Feb 2021
      RRID:AB_2122378

      DOI: 10.1016/j.celrep.2021.108729

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    sciencedirect.com/science/article/pii/S2211124721000425
  49. Sep 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Insulin-Like Growth Factor-1 Inhibits Spreading Depression-Induced Trigeminal Calcitonin Gene Related Peptide, Oxidative Stress & Neuronal Activation in Rat
    1
    1. scibot 16 Sep 2020
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      DOI: 10.1016/j.brainres.2020.146673

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    sciencedirect.com/science/article/pii/S0006899320300299
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    Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling
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      DOI: 10.1016/j.celrep.2020.108007

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    sciencedirect.com/science/article/pii/S221112472030992X
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disc1 Carrier Mice Exhibit Alterations in Neural pIGF-1Rβ and Related Kinase Expression
    1
    1. scibot 04 Sep 2020
      Rabbit anti-IGF1-Rβ

      DOI: 10.3389/fncel.2020.00094

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    ncbi.nlm.nih.gov/pmc/articles/PMC7214624/
  53. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      rabbit anti-IGF-1R

      DOI: 10.3390/cells9010147

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    mdpi.com/2073-4409/9/1/147
  54. Jan 2020
  55. www.sciencedirect.com www.sciencedirect.com
    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
    1
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      DOI: 10.1016/j.yexcr.2018.11.006

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    sciencedirect.com/science/article/pii/S0014482718308218
  56. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.04.034

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    sciencedirect.com/science/article/pii/S2211124719304991
  57. academic.oup.com academic.oup.com
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      DOI: 10.1210/en.2019-00132

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    academic.oup.com/endo/article/160/6/1439/5474882
  58. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.02.081

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    sciencedirect.com/science/article/pii/S2211124719302670
  59. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_2122378

      DOI: 10.1016/j.cell.2019.02.030

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    sciencedirect.com/science/article/pii/S0092867419302132
  60. Nov 2018
  61. jcb.rupress.org jcb.rupress.org
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    jcb.rupress.org/content/217/10/3480
  62. jcb.rupress.org jcb.rupress.org
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    jcb.rupress.org/content/early/2018/08/17/jcb.201801085
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  64. academic.oup.com academic.oup.com
    Selective androgen receptor modulator S42 suppresses prostate cancer cell proliferation
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      Curator: @evieth

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    academic.oup.com/endo/article/159/4/1774/4850601
  65. Nov 2017
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  67. academic.oup.com academic.oup.com
    Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model
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      Curator: @bandrow

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    academic.oup.com/endo/article/158/3/560/2930939/Dual-Role-of-Insulin-in-Spexin-Regulation
  68. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    sciencedirect.com/science/article/pii/S2405471216304082
  69. www.sciencedirect.com www.sciencedirect.com
    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
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    1. scibot 08 Nov 2017
      AB_2122378

      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S1550413117300943