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Virus-induced deconjugation of ISG15 dysregulates innate immunity and cellular metabolism

1
1. scibot 09 Aug 2026
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.immuni.2026.07.007
  
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sciencedirect.com/science/article/pii/S1074761326003067
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma

1
1. scibot 10 Jun 2026
  
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  RRID:AB_2126308
  
  DOI: 10.1158/0008-5472.CAN-25-3195
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13244386/
Jan 2026
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A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages

1
1. scibot 29 Jan 2026
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.immuni.2025.12.010
  
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sciencedirect.com/science/article/pii/S1074761325005667
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever

1
1. scibot 22 Jan 2026
  
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  RRID:AB_2126308
  
  DOI: 10.1038/s44321-025-00347-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12808722/
Jul 2025
52.53.155.43 52.53.155.43

Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15

1
1. scibot 16 Jul 2025
  
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  AB_2126308
  
  DOI: 10.1101/2023.03.16.533020
  
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52.53.155.43/afb5e6b037ad2f349bd7a3112c88e9d2144c43dd/2023.03.16.533020v1.full-html.html
Feb 2025
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RSAD2: A pathogenic interferon-stimulated gene at the maternal-fetal interface of patients with systemic lupus erythematosus

1
1. scibot 21 Feb 2025
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.xcrm.2025.101974
  
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sciencedirect.com/science/article/pii/S2666379125000473
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy

1
1. scibot 07 Nov 2024
  
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  RRID:AB_2126308
  
  DOI: 10.3389/fonc.2024.1441935
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
Aug 2024
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Disruption of glucose homeostasis by bacterial infection orchestrates host innate immunity through NAD+/NADH balance

1
1. scibot 22 Aug 2024
  
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  AB_2126308
  
  DOI: 10.1016/j.celrep.2024.114648
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S2211124724009999
Jul 2024
www.cell.com www.cell.com

CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection

1
1. scibot 19 Jul 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2024.114405
  
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cell.com/cell-reports/abstract/S2211-1247(24)00734-4
May 2024
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

1
1. scibot 21 May 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.cell.2024.04.025
  
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sciencedirect.com/science/article/pii/S0092867424004513
Apr 2024
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Blocking cGAS-STING pathway promotes post-stroke functional recovery in an extended treatment window via facilitating remyelination

1
1. scibot 25 Apr 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.medj.2024.03.018
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S2666634024001302
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells

1
1. scibot 10 Apr 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1158/2767-9764.CRC-23-0488
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
Mar 2024
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HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity

2
1. scibot 01 Mar 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2024.113870
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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  RRID:AB_2126308
2. scibot 01 Mar 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2024.113870
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S2211124724001980
Jan 2024
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Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

1
1. scibot 23 Jan 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2024.113684
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S2211124724000123
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

1
1. scibot 09 Jan 2024
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.ccell.2023.12.005
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S1535610823004336
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression

1
1. scibot 30 Nov 2023
  
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  RRID:AB_2126308
  
  DOI: 10.1158/2767-9764.CRC-23-0265
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
Oct 2023
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Regulation of STING activity in DNA sensing by ISG15 modification

1
1. scibot 27 Oct 2023
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2023.113277
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S2211124723012895
Feb 2023
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Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

1
1. scibot 03 Feb 2023
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.cell.2022.12.038
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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sciencedirect.com/science/article/pii/S0092867422015811
Nov 2022
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 22 Nov 2022
  
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  RRID:AB_2126308
  
  DOI: 10.1002/1878-0261.13322
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13322
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

1
1. scibot 23 Oct 2021
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.isci.2021.103173
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8517841/
Mar 2021
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Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine

1
1. scibot 03 Mar 2021
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2021.108798
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_2126308
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sciencedirect.com/science/article/pii/S2211124721001121
Dec 2020
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Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing

1
1. scibot 23 Dec 2020
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.scr.2020.102135
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
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  RRID:AB_2126308 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1873506120304360
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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

1
1. scibot 17 Dec 2020
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2020.108493
  
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  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_2126308
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sciencedirect.com/science/article/pii/S2211124720314820
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO

1
1. scibot 26 Sep 2020
  
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  RRID:AB_2126308
  
  DOI: 10.7554/eLife.56095
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_2126308
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ncbi.nlm.nih.gov/pmc/articles/PMC7145425/
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Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions

1
1. scibot 07 Sep 2020
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2020.107633
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_2126308
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sciencedirect.com/science/article/pii/S2211124720305866
Jan 2020
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Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.chom.2019.09.012
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
  Curator: @ethanbadger
  
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  RRID:AB_2126308 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1931312819304792
www.sciencedirect.com www.sciencedirect.com

Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2019.09.039
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
  Curator: @ethanbadger
  
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  RRID:AB_2126308 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719312276
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SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2126308
  
  DOI: 10.1016/j.celrep.2019.06.027
  
  Resource: (Santa Cruz Biotechnology Cat# sc-166755, RRID:AB_2126308)
  
  Curator: @ethanbadger
  
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  RRID:AB_2126308 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719307934
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2126308
  
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sciencedirect.com/science/article/pii/S1074761318303261
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LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2126308
  
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sciencedirect.com/science/article/pii/S0092867418307153