53 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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    1. scibot 03 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
  3. Mar 2024
  4. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
    3
    1. scibot 07 Mar 2024
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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  5. Feb 2024
  6. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
    1
    1. scibot 09 Feb 2024
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    52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
  7. Dec 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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    1. scibot 01 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
  9. Aug 2023
  10. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
    1
    1. scibot 05 Aug 2023
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      DOI: 10.1016/j.isci.2023.107449

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    sciencedirect.com/science/article/pii/S2589004223015262
  11. Jul 2023
  12. www.nature.com www.nature.com
    MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
    1
    1. scibot 14 Jul 2023
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      DOI: 10.1038/s41536-023-00310-6

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    nature.com/articles/s41536-023-00310-6
  13. Apr 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Regulation of sertoli cell function by planar cell polarity (PCP) protein Fjx1
    1
    1. scibot 29 Apr 2023
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    sciencedirect.com/science/article/pii/S0303720723000874
  15. Mar 2023
  16. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
    2
    1. scibot 16 Mar 2023
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      DOI: 10.15252/embj.2022112126

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    embopress.org/doi/10.15252/embj.2022112126
  17. Dec 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning
    1
    1. scibot 08 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722016497
  19. Oct 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.
    1
    1. scibot 27 Oct 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9589172/
  21. www.sciencedirect.com www.sciencedirect.com
    Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer
    1
    1. scibot 05 Oct 2022
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    sciencedirect.com/science/article/pii/S2211124722012840
  22. Sep 2022
  23. www.sciencedirect.com www.sciencedirect.com
    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
    1
    1. scibot 29 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722012530
  24. Aug 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111296

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    sciencedirect.com/science/article/pii/S2211124722011160
  26. Jun 2022
  27. link.springer.com link.springer.com
    The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1186/s12964-022-00843-1

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    link.springer.com/article/10.1186/s12964-022-00843-1
  28. May 2022
  29. www.sciencedirect.com www.sciencedirect.com
    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
    1
    1. scibot 13 May 2022
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      DOI: 10.1016/j.isci.2022.104316

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    sciencedirect.com/science/article/pii/S2589004222005879
  30. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
    1
    1. scibot 05 May 2022
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      DOI: 10.1016/j.cell.2022.04.014

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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  31. Apr 2022
  32. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
    1
    1. scibot 20 Apr 2022
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      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  33. Mar 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
    1
    1. scibot 11 Mar 2022
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      DOI: 10.1038/s41598-022-07600-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
  35. Feb 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
    1
    1. scibot 16 Feb 2022
      RRID:AB_2133513

      DOI: 10.1016/j.celrep.2022.110390

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    sciencedirect.com/science/article/pii/S2211124722001115
  37. Oct 2021
  38. www.sciencedirect.com www.sciencedirect.com
    Glycogen accumulation and phase separation drives liver tumor initiation
    1
    1. scibot 22 Oct 2021
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      DOI: 10.1016/j.cell.2021.10.001

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    sciencedirect.com/science/article/pii/S0092867421011752
  39. Aug 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
    1
    1. scibot 28 Aug 2021
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      DOI: 10.1016/j.molcel.2021.07.040

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    sciencedirect.com/science/article/pii/S1097276521006249
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    Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
    1
    1. scibot 25 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109596

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    sciencedirect.com/science/article/pii/S2211124721010342
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    Untitled document
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    1. scibot 02 Aug 2021
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      DOI: 10.1016/j.ccell.2018.11.006

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    sciencedirect.com/science/article/pii/S1535610818305270
  43. Jul 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.cub.2018.11.066

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    ncbi.nlm.nih.gov/pmc/articles/PMC6345631/
  45. May 2021
  46. www.sciencedirect.com www.sciencedirect.com
    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
    1
    1. scibot 01 May 2021
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      DOI: 10.1016/j.molcel.2021.04.009

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    sciencedirect.com/science/article/pii/S1097276521003142
  47. Mar 2021
  48. www.sciencedirect.com www.sciencedirect.com
    S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
    1
    1. scibot 29 Mar 2021
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      DOI: 10.1016/j.chembiol.2021.01.004

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    sciencedirect.com/science/article/pii/S2451945621000040
  49. Dec 2020
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
    1
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      DOI: 10.1016/j.molcel.2020.11.028

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    ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
  51. Oct 2020
  52. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
    1
    1. scibot 27 Oct 2020
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      DOI: 10.1016/j.celrep.2020.108284

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    sciencedirect.com/science/article/pii/S2211124720312730
  53. Sep 2020
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration
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      DOI: 10.7554/eLife.55771

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    ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
  55. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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      DOI: 10.1016/j.ccell.2019.12.006

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    sciencedirect.com/science/article/pii/S1535610819305768
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    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
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      DOI: 10.1016/j.celrep.2020.107860

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    sciencedirect.com/science/article/pii/S221112472030841X
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    A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling
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      DOI: 10.1016/j.celrep.2020.108118

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    sciencedirect.com/science/article/pii/S2211124720311074
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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      DOI: 10.1158/0008-5472.CAN-18-4075

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    ncbi.nlm.nih.gov/pmc/articles/PMC6726494/
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    mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury
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      DOI: 10.1016/j.immuni.2020.02.002

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    sciencedirect.com/science/article/pii/S107476132030073X
  60. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
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      DOI: 10.1016/j.cmet.2020.03.010

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    sciencedirect.com/science/article/pii/S155041312030125X
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1
    1
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      DOI: 10.1016/j.celrep.2019.11.035

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    sciencedirect.com/science/article/pii/S2211124719315177
  63. elifesciences.org elifesciences.org
    CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.7554/eLife.46012

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    elifesciences.org/articles/46012
  64. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.cub.2018.11.066

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    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.ccell.2019.01.009

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    1. scibot 13 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.devcel.2019.04.018

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    sciencedirect.com/science/article/pii/S1534580719302990
  67. www.sciencedirect.com www.sciencedirect.com
    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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    1. scibot 12 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.molcel.2018.10.030

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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
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    1. scibot 12 Jan 2020
      RRID:AB_2133513

      DOI: 10.1016/j.devcel.2018.12.021

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    sciencedirect.com/science/article/pii/S1534580718311171
  69. Nov 2018
  70. www.sciencedirect.com www.sciencedirect.com
    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
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      Curator: @Jmenke

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    The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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    Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores
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    sciencedirect.com/science/article/pii/S0092867417311923
  74. Nov 2017
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    The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
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      3477

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    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
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    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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      AB_2133513

      Curator: @kaitlinsung

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    Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
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    1. scibot 08 Nov 2017
      AB_2133513

      Curator: @kaitlinsung

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