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IGF2 acts downstream of Hippo signaling to regulate organ growth and restore liver regeneration in aging

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1. scibot 09 Sep 2026
  
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  DOI: 10.1016/j.stem.2026.08.006
  
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sciencedirect.com/science/article/pii/S1934590926003073
Aug 2026
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Blocking L-carnitine synthesis by meldonium prolongs the survival in mice with pancreatic cancer

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1. scibot 08 Aug 2026
  
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  DOI: 10.1016/j.isci.2026.117071
  
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sciencedirect.com/science/article/pii/S2589004226024491
Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ATM Deficiency Induces TGFβ-Mediated Stromal Programming in Pancreatic Cancer

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1. scibot 17 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-26-0138
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13370118/
54.241.53.176 54.241.53.176

huang-et-al-2025-cdk5rap3-mediated-regulation-of-lysosomal-and-er-membrane-proteins-is-pivotal-for-the-survival-and-html.html

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1. scibot 09 Jul 2026
  
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  DOI: 10.1152/ajpcell.00284.2025
  
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54.241.53.176/19603908de2c4d3834b600abd2d3062b6121e6b6/huang-et-al-2025-cdk5rap3-mediated-regulation-of-lysosomal-and-er-membrane-proteins-is-pivotal-for-the-survival-and-html.html
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Patient-derived organoids reveal ductal dysfunction and CFTR-modulator responses in chronic pancreatitis

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1. scibot 03 Jul 2026
  
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  DOI: 10.1016/j.stem.2026.06.002
  
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sciencedirect.com/science/article/pii/S1934590926002286
Jun 2026
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Inactivation of CDKN2AARF Promotes p53-Independent Remodeling of the PDAC Tumor Microenvironment

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1. scibot 25 Jun 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-1969
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13290023/
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Diet-induced phospholipid remodeling dictates ferroptosis sensitivity and tumorigenesis in the pancreas

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1. scibot 05 Jun 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0734
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13227558/
May 2026
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression

1
1. scibot 07 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117324
  
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sciencedirect.com/science/article/pii/S221112472600402X
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A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.ccell.2026.03.021
  
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sciencedirect.com/science/article/pii/S1535610826001753
Apr 2026
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Unbiased niche labeling maps immune-excluded niche in bone metastasis

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1. scibot 30 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.04.009
  
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sciencedirect.com/science/article/pii/S0092867426003983
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Regulatory elements in the Sox9 locus license the initiation of pancreatic ductal adenocarcinoma

1
1. scibot 16 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117176
  
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sciencedirect.com/science/article/pii/S2211124726002548
Mar 2026
54.241.53.176 54.241.53.176

2026.03.09.710643.full-html.html

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1. scibot 19 Mar 2026
  
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  DOI: 10.64898/2026.03.09.710643
  
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54.241.53.176/a51c42df6b8b294bc9cf9bac211564d122eddeef/2026.03.09.710643.full-html.html
Feb 2026
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Unveiling critical signaling pathways in the murine salivary gland and the role of midkine

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114852
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12925232/
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1-s2.0-S258900422600324X-main-html.html

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1. scibot 10 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114949
  
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54.241.53.176/6dcb7acadbcb87ffa285f9ca9b079d23cad9b8bf/1-s2.0-S258900422600324X-main-html.html
Jan 2026
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Defects in nephrogenesis result in an expansion of the Foxd1+ stromal progenitor population

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1. scibot 30 Jan 2026
  
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  AB_2133570
  
  DOI: 10.1242/dev.204964
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12848570/
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A Jagged1-regulated hybrid-EMT state identifies pancreatic cancer stem cells

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1. scibot 27 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116909
  
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sciencedirect.com/science/article/pii/S221112472501681X
Dec 2025
54.241.53.176 54.241.53.176

2025.12.06.692782.full-html.html

1
1. scibot 23 Dec 2025
  
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  AB_2133570
  
  DOI: 10.64898/2025.12.06.692782
  
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54.241.53.176/fbd0886bd2a440c71db224f7b73648e10705c43c/2025.12.06.692782.full-html.html
54.241.53.176 54.241.53.176

2025.12.05.692494.full-html.html

2
1. scibot 14 Dec 2025
  
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  DOI: 10.64898/2025.12.05.692494
  
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  DOI: 10.64898/2025.12.05.692494
  
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54.241.53.176/859d61b0a1881682ec83d75944c9c8d21fa97b49/2025.12.05.692494.full-html.html
54.241.53.176 54.241.53.176

1-s2.0-S2589004225025519-main-html.html

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1. scibot 14 Dec 2025
  
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  DOI: 10.1016/j.isci.2025.114290
  
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54.241.53.176/8c76358cffbdca3590659296903fbb7ba84db3c2/1-s2.0-S2589004225025519-main-html.html
Nov 2025
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Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116557
  
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sciencedirect.com/science/article/pii/S2211124725013282
Oct 2025
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Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116487
  
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sciencedirect.com/science/article/pii/S2211124725012586
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Bone-Induced Her2 Promotes Secondary Metastasis in HR+/Her2− Breast Cancer

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1. scibot 03 Oct 2025
  
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  DOI: 10.1158/2159-8290.CD-23-0543
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11964846/
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Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.003
  
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sciencedirect.com/science/article/pii/S1535610825003952
Sep 2025
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RACK1 attenuates pancreatic tumorigenesis by suppressing acinar-to-ductal metaplasia through inflammatory signaling modulation

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1. scibot 06 Sep 2025
  
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  DOI: 10.1007/s13402-025-01084-3
  
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link.springer.com/article/10.1007/s13402-025-01084-3
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Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

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1. scibot 04 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.08.013
  
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sciencedirect.com/science/article/pii/S0092867425009274
Aug 2025
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HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.cmet.2025.07.007
  
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cell.com/cell-metabolism/abstract/S1550-4131(25)00334-1
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BPS Publications

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1. scibot 01 Aug 2025
  
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  DOI: 10.1111/bph.70137
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70137
Jul 2025
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Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer

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  DOI: 10.1016/j.ccell.2025.06.021
  
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sciencedirect.com/science/article/pii/S1535610825002715
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Targeting ZNRF3 and RNF43 to Restore Regeneration and Reverse Metabolic Dysfunction-Associated Steatotic Liver Disease

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1. scibot 01 Jul 2025
  
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  DOI: 10.1101/2025.06.19.660551
  
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biorxiv.org/content/10.1101/2025.06.19.660551v1
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Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration

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  DOI: 10.1016/j.devcel.2025.06.007
  
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sciencedirect.com/science/article/pii/S1534580725003624
Jun 2025
www.cell.com www.cell.com

HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury

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1. scibot 24 Jun 2025
  
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  DOI: 10.1016/j.stem.2025.04.010
  
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cell.com/cell-stem-cell/abstract/S1934-5909(25)00177-8
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Protocol for adeno-associated virus-mediated gene delivery to accelerate pancreatic carcinogenesis in mice

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.xpro.2025.103907
  
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sciencedirect.com/science/article/pii/S2666166725003132
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dual Role of NRF2 in Pancreatic Precursor Lesions

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1. scibot 13 Jun 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0107
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12158068/
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Trametinib potentiates anti-PD-1 efficacy in tumors established from chemotherapy-primed pancreatic cancer cells

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1. scibot 11 Jun 2025
  
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  DOI: 10.1158/1535-7163.MCT-23-0833
  
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May 2025
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Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization

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Ductal or Ngn3+ cells do not contribute to adult pancreatic islet beta-cell neogenesis in homeostasis

1
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  DOI: 10.1038/s44318-025-00434-z
  
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Apr 2025
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Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis

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Ductal or Ngn3+ cells do not contribute to adult pancreatic islet beta-cell neogenesis in homeostasis

1
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Feb 2025
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A new effLuc/Kate dual reporter allele for tumor imaging in mice

1
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

1
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  DOI: 10.1126/scitranslmed.adj9366
  
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Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

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Nov 2024
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Jag1 insufficiency alters liver fibrosis via T cell and hepatocyte differentiation defects

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Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer

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Aug 2024
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FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia

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May 2024
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The Janus kinase 1 is critical for pancreatic cancer initiation and progression

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Apr 2024
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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

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Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

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Tracing the origin of alveolar stem cells in lung repair and regeneration

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Mar 2024
52.53.155.43 52.53.155.43

Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons

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  DOI: 10.1038/s44319-024-00066-0
  
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PRMT1 promotes pancreatic cancer development and resistance to chemotherapy

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Feb 2024
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Loss of TIM4-Dependent Efferocytosis in Kupffer Cells Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

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Oct 2023
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Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing

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Aug 2023
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Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development

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Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression

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Jun 2023
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Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time

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Apr 2023
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Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors

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Mar 2023
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Two Hippo signaling modules orchestrate liver size and tumorigenesis

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  DOI: 10.15252/embj.2022112126
  
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Feb 2023
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Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer

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Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells

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  DOI: 10.1158/2159-8290.CD-22-0220
  
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Dec 2022
52.53.155.43 52.53.155.43

cd-22-0220-html.html

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Nov 2022
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Loss of Hepatic Lgr4 and Lgr5 Promotes Nonalcoholic Fatty Liver Disease

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Oct 2022
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Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

1
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Aug 2022
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Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids

1
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  DOI: 10.1016/j.xpro.2022.101656
  
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Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma

1
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Apr 2022
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Rapid fluorescent vital imaging of olfactory epithelium

2
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Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer

1
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

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An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function

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Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin

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A mechanistic basis for the malignant progression of salivary gland tumors

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Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation

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FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis

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A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice

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Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development

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A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling

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Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors

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Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion

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ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation

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Cell of Origin Influences Pancreatic Cancer Subtype

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The bone microenvironment invigorates metastatic seeds for further dissemination

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PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression

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DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

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Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

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Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis

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Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer

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Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

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Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

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α-Ketoglutarate links p53 to cell fate during tumour suppression

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A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas

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AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

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Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice

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Modeling Human Cancer-induced Cachexia

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  DOI: 10.1016/j.stem.2019.04.015
  
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Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry

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A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer

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SOX2 regulates acinar cell development in the salivary gland

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Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

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FGF21 Is an Exocrine Pancreas Secretagogue

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