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  1. Last 7 days
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    Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency
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    medrxiv.org/content/10.64898/2026.05.23.26353575v1
  3. Jun 2025
  4. www.nature.com www.nature.com
    GSDME-mediated pyroptosis in microglia exacerbates demyelination and neuroinflammation in multiple sclerosis: insights from humans and cuprizone-induced demyelination model mice
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    nature.com/articles/s41418-025-01537-0
  5. Mar 2025
  6. www.sciencedirect.com www.sciencedirect.com
    TMEM63B functions as a mammalian hyperosmolar sensor for thirst
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    sciencedirect.com/science/article/pii/S0896627325001308
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    Induction of MASH-like pathogenesis in the Nwd1−/− mouse liver
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    nature.com/articles/s42003-025-07717-5
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    KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids
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    sciencedirect.com/science/article/pii/S089662732500114X
  9. Dec 2024
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity
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  11. 52.53.155.43 52.53.155.43
    Longitudinal autophagy profiling of the mammalian brain reveals sustained mitophagy throughout healthy aging
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    52.53.155.43/b177ba73869c9e2ad0053b7f490e74c5426bcd4b/rappe-et-al-2024-longitudinal-autophagy-profiling-of-the-mammalian-brain-reveals-sustained-mitophagy-throughout-healthy-html.html
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    Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain
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    sciencedirect.com/science/article/pii/S2211124724013676
  13. Aug 2024
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    Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
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    sciencedirect.com/science/article/pii/S2211124724009379
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    Sestrin2 drives ER-phagy in response to protein misfolding
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  17. Jul 2024
  18. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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  19. May 2024
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    Induction of NASH in the Nwd1−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress
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    biorxiv.org/content/10.1101/2024.01.26.577307v2
  21. Apr 2024
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    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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  23. Mar 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The IgCAM BT-IgSF (IgSF11) Is Essential for Connexin43-Mediated Astrocyte–Astrocyte Coupling in Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10957231/
  25. Sep 2023
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    Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/10.1002/glia.24461
  27. Jun 2023
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    Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15876
  29. Jan 2023
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    Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes
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    sciencedirect.com/science/article/pii/S2211124722018733
  31. Sep 2022
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    Target protein localization and its impact on PROTAC-mediated degradation
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    sciencedirect.com/science/article/pii/S2451945622003129
  33. Aug 2022
  34. www.embopress.org www.embopress.org
    Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons
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    embopress.org/doi/10.15252/embj.2021110486
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    Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
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    sciencedirect.com/science/article/pii/S1934590922003046
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    Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
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    sciencedirect.com/science/article/pii/S2211124722009809
  37. Jul 2022
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    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
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    sciencedirect.com/science/article/pii/S258900422200904X
  39. Jan 2022
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    Mosaic dysfunction of mitophagy in mitochondrial muscle disease
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    sciencedirect.com/science/article/pii/S1550413121006367
  41. Nov 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Involvement of the miR-363-5p/P2RX4 Axis in Regulating Schwann Cell Phenotype after Nerve Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC8584002/
  43. Sep 2021
  44. elifesciences.org elifesciences.org
    The amyloid precursor protein is a conserved Wnt receptor
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    elifesciences.org/articles/69199
  45. Aug 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6327111/
  47. journals.sagepub.com journals.sagepub.com
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    journals.sagepub.com/doi/abs/10.1177/1759091419838949
  48. Jul 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6257821/
  50. Apr 2021
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    Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
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    sciencedirect.com/science/article/pii/S1550413120303594
  52. Mar 2021
  53. www.mdpi.com www.mdpi.com
    Rapid and Progressive Loss of Multiple Retinal Cell Types in Cathepsin D-Deficient Mice—An Animal Model of CLN10 Disease
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    mdpi.com/2073-4409/10/3/696/htm
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain
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    ncbi.nlm.nih.gov/pmc/articles/PMC7116799/
  55. Feb 2021
  56. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.15350
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heme Oxygenase 1 in Schwann Cells Regulates Peripheral Nerve Degeneration Against Oxidative Stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC6498775/
  58. Oct 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome
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    sciencedirect.com/science/article/pii/S0896627320307108
  60. Sep 2020
  61. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction
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    pubmed.ncbi.nlm.nih.gov/32959911/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface
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    ncbi.nlm.nih.gov/pmc/articles/PMC7340497/
  63. academic.oup.com academic.oup.com
    Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1
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    academic.oup.com/jb/article/doi/10.1093/jb/mvaa076/5870373
  64. Jan 2020
  65. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1934590918305496
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC6282074/
  67. Nov 2018
  68. www.sciencedirect.com www.sciencedirect.com
    Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
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    sciencedirect.com/science/article/pii/S0092867418309772
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
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    ncbi.nlm.nih.gov/pmc/articles/PMC5807059/
  70. Nov 2017
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC5249261/