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40 Matching Annotations

Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

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1. scibot 21 Mar 2026
  
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  DOI: 10.3389/fimmu.2026.1776302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12992265/
Jan 2026
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HRD1 negatively regulates autolysosome formation by inhibiting liquid-liquid phase separation of SNAP29

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116914
  
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sciencedirect.com/science/article/pii/S2211124725016869
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Membrane-protein-mediated phase separation orchestrates organelle contact sites

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  DOI: 10.1016/j.molcel.2025.12.006
  
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sciencedirect.com/science/article/pii/S1097276525009803
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Gut dysbiosis leads to cognitive decline through CNTF-mediated activation of microglia in mice

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  DOI: 10.1186/s12915-025-02454-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12670871/
Sep 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

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  DOI: 10.1002/advs.202503082
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202503082
Jul 2025
rupress.org rupress.org

B cell mechanotransduction via ATAT1 coordinates actin and lysosomal dynamics at the immune synapse

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  DOI: 10.1083/jcb.202407181
  
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rupress.org/jcb/article/224/8/e202407181/278133/B-cell-mechanotransduction-via-ATAT1-coordinates
elifesciences.org elifesciences.org

The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

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1. scibot 08 Jul 2025
  
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  DOI: 10.7554/eLife.101984
  
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elifesciences.org/articles/101984
May 2025
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Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cells

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.007
  
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sciencedirect.com/science/article/pii/S009286742500409X
Apr 2025
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Excessive expression of progranulin leads to neurotoxicity rather than neuroprotection

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  DOI: 10.1016/j.nbd.2025.106895
  
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sciencedirect.com/science/article/pii/S0969996125001111
Mar 2025
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IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

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1. scibot 11 Mar 2025
  
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  DOI: 10.1002/advs.202501593
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202501593
Feb 2025
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Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115333
  
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sciencedirect.com/science/article/pii/S2211124725001044
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Presenilins as hub proteins controlling the endocytic and autophagic pathways and small extracellular vesicle secretion

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1. scibot 18 Jan 2025
  
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  DOI: 10.1002/jev2.70019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11735957/
Apr 2024
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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

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  DOI: 10.1016/j.celrep.2024.114096
  
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sciencedirect.com/science/article/pii/S2211124724004248
Dec 2023
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Lysosomal dynamics regulate mammalian cortical neurogenesis

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  DOI: 10.1016/j.devcel.2023.11.021
  
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sciencedirect.com/science/article/pii/S1534580723006196
Apr 2023
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Cellular proteins act as surfactants to control the interfacial behavior and function of biological condensates

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.04.004
  
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sciencedirect.com/science/article/pii/S1534580723001570
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C9ORF72 suppresses JAK-STAT mediated inflammation

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106579
  
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sciencedirect.com/science/article/pii/S2589004223006569
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection

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1. scibot 14 Apr 2023
  
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  DOI: 10.3389/fphar.2023.1142639
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10090407/
Dec 2022
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Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models

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1. scibot 04 Dec 2022
  
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  DOI: 10.1016/j.xpro.2022.101891
  
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sciencedirect.com/science/article/pii/S2666166722007717
Nov 2022
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Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease

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1. scibot 11 Nov 2022
  
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  DOI: 10.1016/j.neuron.2022.10.021
  
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sciencedirect.com/science/article/pii/S0896627322009540
Oct 2022
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Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes

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1. scibot 18 Oct 2022
  
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  DOI: 10.1016/j.cmet.2022.09.022
  
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sciencedirect.com/science/article/pii/S1550413122004120
Apr 2022
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Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

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1. scibot 20 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.018
  
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sciencedirect.com/science/article/pii/S1074761322001418
Nov 2021
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ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress

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1. scibot 09 Nov 2021
  
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sciencedirect.com/science/article/pii/S1534580721008078
Aug 2021
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Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis

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1. scibot 18 Aug 2021
  
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  DOI: 10.1016/j.xcrm.2021.100370
  
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sciencedirect.com/science/article/pii/S266637912100224X
advances.sciencemag.org advances.sciencemag.org

Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation

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1. scibot 17 Aug 2021
  
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  DOI: 10.1126/sciadv.abf6580
  
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advances.sciencemag.org/content/7/32/eabf6580
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.052
  
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sciencedirect.com/science/article/pii/S2211124718318151
onlinelibrary.wiley.com onlinelibrary.wiley.com

The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C

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1. scibot 08 Aug 2021
  
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  DOI: 10.1111/jnc.14110
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14110
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.052
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6302547/
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Untitled document

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  DOI: 10.1111/jnc.14110
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5630500/
Jul 2021
www.nature.com www.nature.com

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

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1. scibot 29 Jul 2021
  
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  DOI: 10.1038/s41467-019-11568-0
  
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nature.com/articles/s41467-019-11568-0
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Neuronal VCP loss of function recapitulates FTLD-TDP pathology

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sciencedirect.com/science/article/pii/S221112472100797X
May 2021
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Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.10.010
  
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sciencedirect.com/science/article/pii/S1534580720308005
Apr 2021
www.cell.com www.cell.com

β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells

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1. scibot 08 Apr 2021
  
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  DOI: 10.1016/j.cub.2021.01.081
  
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cell.com/current-biology/abstract/S0960-9822(21)00146-9
Feb 2021
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ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

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1. scibot 28 Feb 2021
  
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  DOI: 10.1016/j.devcel.2020.12.010
  
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sciencedirect.com/science/article/pii/S1534580720310169
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption

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1. scibot 22 Nov 2020
  
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  DOI: 10.1016/j.cell.2020.08.048
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7646275/
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Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

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1. scibot 13 Nov 2020
  
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  DOI: 10.1016/j.neuron.2020.10.005
  
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sciencedirect.com/science/article/pii/S089662732030773X
Jan 2020
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The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1

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1. scibot 13 Jan 2020
  
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  RRID:AB_2134499
  
  DOI: 10.1016/j.molcel.2019.10.035
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1097276519308135
Nov 2018
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Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression

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sciencedirect.com/science/article/pii/S0896627318306834
Nov 2017
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The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

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1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C

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1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake

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1. scibot 08 Nov 2017
  
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  AB_2134499
  
  Curator: @chewbeccax
  
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