56 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
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    1. scibot 18 Apr 2024
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2024.114117

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    sciencedirect.com/science/article/pii/S2211124724004455
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP
    1
    1. scibot 01 Mar 2024
      RRID:AB_3094543

      DOI: 10.1016/j.celrep.2024.113860

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    sciencedirect.com/science/article/pii/S2211124724001888
  5. Dec 2023
  6. www.sciencedirect.com www.sciencedirect.com
    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
    1
    1. scibot 29 Dec 2023
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2023.113540

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    sciencedirect.com/science/article/pii/S2211124723015528
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    Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity
    1
    1. scibot 17 Dec 2023
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2023.113515

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    sciencedirect.com/science/article/pii/S2211124723015279
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    Exploiting the endogenous yeast nuclear proteome to identify short linear motifs in vivo
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.crmeth.2023.100637

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    sciencedirect.com/science/article/pii/S2667237523003089
  9. Nov 2023
  10. www.sciencedirect.com www.sciencedirect.com
    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
    1
    1. scibot 28 Nov 2023
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2023.113414

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    sciencedirect.com/science/article/pii/S2211124723014262
  11. Oct 2023
  12. link.springer.com link.springer.com
    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
    1
    1. scibot 17 Oct 2023
      RRID:AB_10694918

      DOI: 10.1186/s12967-023-04542-4

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    link.springer.com/article/10.1186/s12967-023-04542-4
  13. Sep 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Essential role of the amino-terminal region of Drosha for the Microprocessor function
    1
    1. scibot 30 Sep 2023
      RRID:AB_2136278

      DOI: 10.1016/j.isci.2023.107971

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    sciencedirect.com/science/article/pii/S2589004223020485
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    RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
    1
    1. scibot 30 Sep 2023
      RRID:AB_2136278

      DOI: 10.1016/j.molcel.2023.08.029

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    sciencedirect.com/science/article/pii/S1097276523006937
  16. Aug 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
    1
    1. scibot 31 Aug 2023
      RRID:AB_2136278

      DOI: 10.21203/rs.3.rs-3182731/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10441460/
  18. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
    1
    1. scibot 04 Aug 2023
      RRID:AB_2136278

      DOI: 10.1016/j.ccell.2023.07.005

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    sciencedirect.com/science/article/pii/S1535610823002453
  19. Jun 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
    1
    1. scibot 22 Jun 2023
      RRID:AB_2136278

      DOI: 10.1158/2767-9764.CRC-23-0030

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    ncbi.nlm.nih.gov/pmc/articles/PMC10281290/
  21. aacrjournals.org aacrjournals.org
    Targeting CHAF1B enhances Interferon activity against Myeloproliferative Neoplasm cells
    1
    1. scibot 02 Jun 2023
      RRID:AB_2136278

      DOI: 10.1158/2767-9764.CRC-23-0010

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    aacrjournals.org/cancerrescommun/article/3/5/943/727012/Targeting-CHAF1B-Enhances-IFN-Activity-against
  22. May 2023
  23. 52.53.155.43 52.53.155.43
    PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis
    1
    1. scibot 19 May 2023
      RRID:AB_2136278

      DOI: 10.1210/endocr/bqad065

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    52.53.155.43/bdf89ee8b17f684d89776b136763c0415969fc5a/RRID9-html.html
  24. Mar 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
    1
    1. scibot 09 Mar 2023
      RRID:AB_2136278

      DOI: 10.1016/j.isci.2023.106193

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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  26. Dec 2022
  27. www.sciencedirect.com www.sciencedirect.com
    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
    1
    1. scibot 18 Dec 2022
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2022.111821

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    sciencedirect.com/science/article/pii/S2211124722017132
  28. www.sciencedirect.com www.sciencedirect.com
    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
    1
    1. scibot 08 Dec 2022
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2022.111756

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    sciencedirect.com/science/article/pii/S2211124722016394
  29. Oct 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells
    1
    1. scibot 26 Oct 2022
      RRID:AB_2136278

      DOI: 10.3389/fcvm.2022.979745

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    ncbi.nlm.nih.gov/pmc/articles/PMC9561411/
  31. www.nature.com www.nature.com
    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
    1
    1. scibot 16 Oct 2022
      RRID:AB_2136278

      DOI: 10.1038/s41467-022-33749-0

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    nature.com/articles/s41467-022-33749-0
  32. Sep 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
    1
    1. scibot 11 Sep 2022
      RRID:AB_10694918

      DOI: 10.1016/j.ccell.2022.08.012

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    sciencedirect.com/science/article/pii/S1535610822003762
  34. www.sciencedirect.com www.sciencedirect.com
    Target protein localization and its impact on PROTAC-mediated degradation
    1
    1. scibot 08 Sep 2022
      RRID:AB_2136278

      DOI: 10.1016/j.chembiol.2022.08.004

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    sciencedirect.com/science/article/pii/S2451945622003129
  35. Aug 2022
  36. www.sciencedirect.com www.sciencedirect.com
    LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response
    1
    1. scibot 10 Aug 2022
      RRID:AB_2136278

      DOI: 10.1016/j.isci.2022.104821

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    sciencedirect.com/science/article/pii/S2589004222010938
  37. Jul 2022
  38. www.sciencedirect.com www.sciencedirect.com
    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
    1
    1. scibot 06 Jul 2022
      RRID:AB_2136278

      DOI: 10.1016/j.cmet.2022.06.007

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    sciencedirect.com/science/article/pii/S1550413122002273
  39. Feb 2022
  40. www.sciencedirect.com www.sciencedirect.com
    A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia
    1
    1. scibot 13 Feb 2022
      Cell Signaling, Cat#2032

      DOI: 10.1016/j.jbc.2022.101716

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    sciencedirect.com/science/article/pii/S0021925822001569
  41. Jan 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
    1
    1. scibot 05 Jan 2022
      RRID:AB_2136278

      DOI: 10.1016/j.ccell.2019.04.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC8717880/
  43. Nov 2021
  44. www.sciencedirect.com www.sciencedirect.com
    IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation
    1
    1. scibot 03 Nov 2021
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2021.109926

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    sciencedirect.com/science/article/pii/S2211124721013991
  45. Sep 2021
  46. academic.oup.com academic.oup.com
    CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
    1
    1. scibot 24 Sep 2021
      2032

      DOI: 10.1093/nar/gkab805

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
  47. Aug 2021
  48. www.embopress.org www.embopress.org
    A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication
    1
    1. scibot 31 Aug 2021
      RRID:AB_2136278

      DOI: 10.15252/embj.2021107664

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    embopress.org/doi/abs/10.15252/embj.2021107664
  49. www.sciencedirect.com www.sciencedirect.com
    Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction
    1
    1. scibot 14 Aug 2021
      RRID:AB_2136278

      DOI: 10.1016/j.molcel.2021.07.004

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    sciencedirect.com/science/article/pii/S1097276521005566
  50. academic.oup.com academic.oup.com
    Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models
    1
    1. scibot 07 Aug 2021
      RRID:AB_2136278

      DOI: 10.1210/en.2019-00306

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    academic.oup.com/endo/article/160/11/2673/5552702
  51. Jul 2021
  52. www.sciencedirect.com www.sciencedirect.com
    CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer
    1
    1. scibot 31 Jul 2021
      Lamin A/C

      DOI: 10.1016/j.celrep.2019.10.068

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    sciencedirect.com/science/article/pii/S2211124719313828
  53. www.sciencedirect.com www.sciencedirect.com
    A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication
    2
    1. scibot 28 Jul 2021
      RRID:AB_2136278

      DOI: 10.1016/j.chom.2017.07.017

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      RRID:AB_2136278

      DOI: 10.1016/j.chom.2017.07.017

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    sciencedirect.com/science/article/pii/S1931312817303001
  54. www.sciencedirect.com www.sciencedirect.com
    Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis
    1
    1. scibot 24 Jul 2021
      RRID:AB_2136278

      DOI: 10.1016/j.cmet.2021.07.002

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    sciencedirect.com/science/article/pii/S1550413121003181
  55. Jun 2021
  56. elifesciences.org elifesciences.org
    A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing
    1
    1. scibot 18 Jun 2021
      RRID:AB_2136278

      DOI: 10.7554/eLife.62233

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    elifesciences.org/articles/62233
  57. Jan 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
    1
    1. scibot 26 Jan 2021
      RRID:AB_2136278

      DOI: 10.1016/j.cell.2020.12.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC7868890/
  59. Nov 2020
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
    1
    1. scibot 12 Nov 2020
      RRID:AB_2136278

      DOI: 10.7554/eLife.53550

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    ncbi.nlm.nih.gov/pmc/articles/PMC7641585/
  61. Sep 2020
  62. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
    1
    1. scibot 26 Sep 2020
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2020.108181

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    pubmed.ncbi.nlm.nih.gov/32966797/
  63. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is increased by a naturally occurring elongation variant
    1
    1. scibot 26 Sep 2020
      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2020.108185

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    pubmed.ncbi.nlm.nih.gov/32941788/
  64. www.sciencedirect.com www.sciencedirect.com
    Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
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      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2020.02.007

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  65. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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      RRID:AB_2136278

      DOI: 10.1016/j.cell.2020.03.040

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  66. mcb.asm.org mcb.asm.org
    DEAD Box Protein Family Member DDX28 Is a Negative Regulator of Hypoxia-Inducible Factor 2α- and Eukaryotic Initiation Factor 4E2-Directed Hypoxic Translation
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      anti-lamin A/C

      DOI: 10.1128/MCB.00610-19

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  67. elifesciences.org elifesciences.org
    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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      RRID:AB_2136278

      DOI: 10.7554/eLife.44161

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  68. Jan 2020
  69. www.sciencedirect.com www.sciencedirect.com
    Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium
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      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2019.06.043

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  70. www.sciencedirect.com www.sciencedirect.com
    FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export
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      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2019.06.072

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.44161

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  72. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_2136278

      DOI: 10.1016/j.celrep.2019.02.076

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  73. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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      DOI: 10.1016/j.ccell.2019.01.020

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  74. Nov 2018
  75. www.sciencedirect.com www.sciencedirect.com
    Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals
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      Curator: @Jmenke

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  76. www.sciencedirect.com www.sciencedirect.com
    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
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    1. scibot 05 Nov 2018
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    Small-Molecule TLR8 Antagonists via Structure-Based Rational Design
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  78. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps
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  79. Nov 2017
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The HDAC6 Inhibitor Tubacin Induces Release of CD133+ Extracellular Vesicles from Cancer Cells
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    onlinelibrary.wiley.com/doi/10.1002/jcb.26095/full
  81. www.sciencedirect.com www.sciencedirect.com
    Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis
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  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mesenchyme Homeobox 2 Enhances Migration of Endothelial Colony Forming Cells Exposed to Intrauterine Diabetes Mellitus
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    onlinelibrary.wiley.com/doi/10.1002/jcp.25734/full
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF-κB regulates neuronal ankyrin-G via a negative feedback loop
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      AB_2136278

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