73 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.ymthe.2024.05.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC11405166/
  3. www.sciencedirect.com www.sciencedirect.com
    A TBK1-independent primordial function of STING in lysosomal biogenesis
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S1097276524007032
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    Lamin chromatin binding is modulated by interactions of different LAP2α domains with lamins and chromatin
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2589004224020947
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    PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S1550413124003619
  6. www.biorxiv.org www.biorxiv.org
    Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents
    1
    1. scibot 14 Sep 2024
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      DOI: 10.1101/2024.09.04.611120

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    biorxiv.org/content/10.1101/2024.09.04.611120v1
  7. Jul 2024
  8. www.cell.com www.cell.com
    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114400

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    cell.com/cell-reports/abstract/S2211-1247(24)00728-9
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer
    1
    1. scibot 17 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11246000/
  10. Jun 2024
  11. www.cell.com www.cell.com
    Obg-like ATPase 1 exacerbated gemcitabine drug resistance of pancreatic cancer
    1
    1. scibot 29 Jun 2024
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    cell.com/iscience/fulltext/S2589-0042(24)01252-5
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
    1
    1. scibot 13 Jun 2024
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      DOI: 10.1038/s41467-024-49196-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161513/
  13. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
    1
    1. scibot 06 Jun 2024
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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  14. May 2024
  15. www.science.org www.science.org
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 09 May 2024
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      DOI: 10.1126/sciadv.adl6082

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    science.org/doi/10.1126/sciadv.adl6082
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging
    1
    1. scibot 08 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066433/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 05 May 2024
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      DOI: 10.1126/sciadv.adl6082

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    ncbi.nlm.nih.gov/pmc/articles/PMC11068011/
  18. Apr 2024
  19. www.sciencedirect.com www.sciencedirect.com
    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.021

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    sciencedirect.com/science/article/pii/S1074761324001420
  20. 52.53.155.43 52.53.155.43
    The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis
    1
    1. scibot 11 Apr 2024
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    52.53.155.43/e4a741173d4beb6859350a39a8e5091b3ba2fb02/1-s2.0-S2589004224007314-main-html.html
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
    1
    1. scibot 10 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10999478/
  22. www.sciencedirect.com www.sciencedirect.com
    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
  23. www.sciencedirect.com www.sciencedirect.com
    An integrated multi-omics analysis reveals osteokines involved in global regulation
    2
    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1550413124000858
  24. Mar 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Matrilin-3 supports neuroprotection in ischemic stroke by suppressing astrocyte-mediated neuroinflammation
    1
    1. scibot 27 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003085
  26. link.springer.com link.springer.com
    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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    1. scibot 20 Mar 2024
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      DOI: 10.1007/s00210-024-03045-3

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    link.springer.com/article/10.1007/s00210-024-03045-3
  27. www.sciencedirect.com www.sciencedirect.com
    Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
    2
    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S1550413124000573
  28. www.sciencedirect.com www.sciencedirect.com
    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109231

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    sciencedirect.com/science/article/pii/S2589004224004528
  29. www.sciencedirect.com www.sciencedirect.com
    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.cub.2024.02.038

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    sciencedirect.com/science/article/pii/S0960982224001805
  30. Feb 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1172/JCI173299

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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells
    1
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      DOI: 10.1098/rsob.230407

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    ncbi.nlm.nih.gov/pmc/articles/PMC10805602/
  33. Jan 2024
  34. www.sciencedirect.com www.sciencedirect.com
    A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity
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    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.015

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    sciencedirect.com/science/article/pii/S1097276523010341
  35. www.sciencedirect.com www.sciencedirect.com
    OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB
    1
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      DOI: 10.1016/j.molcel.2023.11.042

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    sciencedirect.com/science/article/pii/S1097276523010195
  36. Dec 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Profibrotic role of transcription factor SP1 in cross-talk between fibroblasts and M2 macrophages
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      DOI: 10.1016/j.isci.2023.108484

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    sciencedirect.com/science/article/pii/S2589004223025610
  38. Oct 2023
  39. www.cell.com www.cell.com
    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
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      DOI: 10.1016/j.isci.2023.108010

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    cell.com/iscience/abstract/S2589-0042(23)02087-4
  40. Sep 2023
  41. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Su-html.html
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    52.53.155.43/78b3cb40c26a3e87d0e680de40f4d0777a8366ee/British J Pharmacology - 2023 - Su-html.html
  42. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Dai-html.html
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    52.53.155.43/8d076c70ed36377d24eb7bc3686db861bc15751d/British J Pharmacology - 2023 - Dai-html.html
  43. Aug 2023
  44. 52.53.155.43 52.53.155.43
    PIIS221112472300952X-html.html
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  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages
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      DOI: 10.1016/j.isci.2023.107376

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    sciencedirect.com/science/article/pii/S2589004223014530
  47. 52.53.155.43 52.53.155.43
    GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
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    1. scibot 18 Jul 2023
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      DOI: 10.15252/embr.202256437

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    52.53.155.43/82562d81b2014f2e2d5c134f5e9ab42cec01f29a/embr.202256437-html.html
  48. Jun 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Dephosphorylation of Six2Y129 protects tyrosine hydroxylase-positive cells in SNpc by regulating TEA domain 1 expression
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      DOI: 10.1016/j.isci.2023.107049

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  50. 52.53.155.43 52.53.155.43
    BPS Publications
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      DOI: 10.1111/bph.16156

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    52.53.155.43/a7694b32aeeb75586321cd0d6d28b4685219f279/British J Pharmacology - 2023 - Chen - Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via-html.html
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    Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
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  52. May 2023
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    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
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  54. Apr 2023
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    Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice
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  56. Mar 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic ZBTB22-mediated Detoxification Ameliorates Acetaminophen-induced Liver Injury by Inhibiting Pregnane X Receptor Signaling
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  58. Feb 2023
  59. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance
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  60. Dec 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways
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  62. www.sciencedirect.com www.sciencedirect.com
    Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation
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  63. Jul 2022
  64. www.nature.com www.nature.com
    Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity
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  65. Jun 2022
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    Very-low-density lipoprotein receptor-enhanced lipid metabolism in pancreatic stellate cells promotes pancreatic fibrosis
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  67. Apr 2022
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    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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  70. Feb 2022
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    Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate
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  72. Aug 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Establishment of a GFP::LMNB1 knockin cell line (CSUi002-A-1) from a dystonia patient-specific iPSC by CRISPR/Cas9 editing
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  74. www.immunohorizons.org www.immunohorizons.org
    3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice
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  75. www.sciencedirect.com www.sciencedirect.com
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  77. Jul 2021
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
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      DOI: 10.7554/eLife.38279

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  79. Apr 2021
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    RNA Demethylase Alkbh5 is Widely Expressed in Neurons and Decreased during Brain Development
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  81. Mar 2021
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior
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  83. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence
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  84. Feb 2021
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d‐galactosamine induced acute liver injury
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  86. Dec 2020
  87. www.sciencedirect.com www.sciencedirect.com
    Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs
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  88. Sep 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function
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    Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival
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  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response
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      DOI: 10.1002/glia.23902

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
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  93. Jan 2020
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury
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  95. www.jbc.org www.jbc.org
    Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia
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  96. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14691

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  97. www.sciencedirect.com www.sciencedirect.com
    Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection
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      DOI: 10.1016/j.immuni.2019.11.015

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    sciencedirect.com/science/article/pii/S1074761319304960
  98. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124719303444
  99. Nov 2017
  100. www.sciencedirect.com www.sciencedirect.com
    Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
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