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Jul 2026
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E3 ubiquitin-ligase Hakai regulates LRP4 stability and Wnt/β-catenin signalling in colorectal cancer cells

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Psychological stress drives aging-like hematopoietic stem cell dysfunction through a brain-gut-bone marrow axis

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  DOI: 10.1016/j.stem.2026.05.012
  
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Jun 2026
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PLGA Nanoparticles Restore Acidic pH and Degradative Function to Compromised Lysosomes with Cy3-Labeling Providing Enhanced Tracking to Lysosomes

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  DOI: 10.1152/ajpcell.00494.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13289670/
May 2026
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TLR7 induces autophagy in non-small cell lung cancer tumor cells and influences anti-tumors responses in patients

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  DOI: 10.21037/tlcr-2025-aw-1173
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13186664/
Apr 2026
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Oxytocin signaling in adipocytes is required for normal milk fat production

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THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells

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  DOI: 10.3390/antiox15030286
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13024539/
Mar 2026
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THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells

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Jan 2026
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Cyclophilin D suppresses colorectal cancer progression through the activation of an autophagy-mediated apoptotic pathway

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pmc.ncbi.nlm.nih.gov/articles/PMC12852878/
Oct 2025
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An in vitro tumor recurrence model based on platinum-resistant colon cancer cells as a research tool for studying cancer cell dormancy

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  DOI: 10.1371/journal.pone.0333671
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12507233/
Aug 2025
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YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition

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  DOI: 10.1016/j.celrep.2025.116188
  
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The elucidation of the dual role of Beclin-1 in ischemic stroke through systems biology modeling

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  DOI: 10.1016/j.isci.2025.113270
  
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sciencedirect.com/science/article/pii/S2589004225015317
Jun 2025
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GSDME-mediated pyroptosis in microglia exacerbates demyelination and neuroinflammation in multiple sclerosis: insights from humans and cuprizone-induced demyelination model mice

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1. scibot 28 Jun 2025
  
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  DOI: 10.1038/s41418-025-01537-0
  
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nature.com/articles/s41418-025-01537-0
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Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity

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1. scibot 18 Jun 2025
  
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  DOI: 10.1124/molpharm.124.000894
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12164689/
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The Effect of FPR2 on the Regulation of Trophoblast Autophagy via the PI3K/AKT/mTOR Signaling Pathway in Preeclampsia

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  DOI: 10.1096/fj.202402938RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202402938RR
Feb 2025
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TFEB/3 govern repair Schwann cell generation and function following peripheral nerve injury

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  DOI: 10.1523/JNEUROSCI.0198-24.2024
  
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jneurosci.org/content/44/35/e0198242024
Sep 2024
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The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization

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  DOI: 10.1016/j.celrep.2024.114689
  
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Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells

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  DOI: 10.1152/ajpcell.00091.2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11371324/
Aug 2024
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Nephron specific ATP6AP2 knockout increases urinary excretion of fatty acids and decreases renal cortical megalin expression

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1. scibot 22 Aug 2024
  
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  DOI: 10.1038/s41598-024-69749-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11319469/
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Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease

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  DOI: 10.1016/j.celrep.2024.114589
  
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Jul 2024
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Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

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ncbi.nlm.nih.gov/pmc/articles/PMC11377155/
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PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection

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Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death

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Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance

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cell.com/cell-reports/fulltext/S2211-1247(24)00738-1
May 2024
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Leucyl-tRNA synthetase contributes to muscle weakness through mTORC1 activation and autophagy suppression in a mouse model of Duchenne Muscular Dystrophy

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SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model

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  DOI: 10.1016/j.xcrm.2024.101570
  
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Apr 2024
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The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle

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  DOI: 10.1038/s41598-024-58716-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10998866/
Feb 2024
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Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma

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  DOI: 10.1016/j.cmet.2024.01.018
  
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cell.com/cell-metabolism/abstract/S1550-4131(24)00018-4
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Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway

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  DOI: 10.1016/j.xcrm.2024.101401
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10897550/
Dec 2023
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Loss of α-1,2-mannosidase MAN1C1 promotes tumorigenesis of intrahepatic cholangiocarcinoma through enhancing CD133-FIP200 interaction

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  DOI: 10.1016/j.celrep.2023.113588
  
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Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

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  DOI: 10.7554/eLife.87098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
Oct 2023
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A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer

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1. scibot 31 Oct 2023
  
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  DOI: 10.3390/cancers15205082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10605716/
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FSHR-mTOR-HIF1 signaling alleviates mouse follicles from AMPK-induced atresia

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  DOI: 10.1016/j.celrep.2023.113158
  
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sciencedirect.com/science/article/pii/S2211124723011701
Sep 2023
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Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.molcel.2023.08.032
  
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The FASEB Journal - 2023 - Yamada (1)-html.html

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  DOI: 10.1096/fj.202300349r
  
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Muscle p62 stimulates the expression of antioxidant proteins alleviating cancer cachexia

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Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis

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TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

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RhoB Promotes Salmonella survival by Regulating Autophagy

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Restored autophagy is protective against PAK3-induced cardiac dysfunction

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Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity

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Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis

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RhoB promotes Salmonella survival by regulating autophagy

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TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

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Ring domains are essential for GATOR2-dependent mTORC1 activation

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Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways

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The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins

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Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment

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Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity

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Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia

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Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

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The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62

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Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model

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Local treatment of a pediatric osteosarcoma model with a 4-1BBL armed oncolytic adenovirus results in an antitumor effect and leads to immune memory

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Mosaic dysfunction of mitophagy in mitochondrial muscle disease

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Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease

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A high-throughput protocol for monitoring starvation-induced autophagy in real time in mouse embryonic fibroblasts

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Function and molecular mechanism of N-terminal acetylation in autophagy

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Non-genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's disease

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ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy

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PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

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Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility

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Untitled document

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Untitled document

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  DOI: 10.1111/jnc.14626
  
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Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-1-regulated apoptosis in pancreatic cancer cells

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Intrinsically Disordered Protein TEX264 Mediates ER-phagy

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  Rabbit polyclonal anti-LC3A/B
  
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Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy

1
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Untitled document

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  DOI: 10.7554/eLife.27134
  
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Annexin A1 Tripeptide Mimetic Increases Sirtuin-3 and Augments Mitochondrial Function to Limit Ischemic Kidney Injury

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  DOI: 10.3389/fphys.2021.683098
  
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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

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  DOI: 10.1016/j.celrep.2021.109321
  
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ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

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Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis

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Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer’s Disease

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  DOI: 10.1016/j.pneurobio.2021.102031
  
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Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling

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  DOI: 10.1093/cercor/bhz306
  
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ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy

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  LC3A/B
  
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ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy

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Dec 2020
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Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

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1. scibot 22 Dec 2020
  
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  anti-LC3
  
  DOI: 10.3390/antiox9121299
  
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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

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  DOI: 10.1016/j.bbi.2020.09.017
  
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sciencedirect.com/science/article/pii/S0889159120315804
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Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients

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  DOI: 10.1038/s12276-020-0413-1
  
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High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy

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  DOI: 10.1002/brb3.1740
  
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Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection

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  DOI: 10.1016/j.chom.2020.01.023
  
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β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy

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  RRID: AB_2137703
  
  DOI: 10.1096/fj.201902305R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902305R
Jan 2020
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Angiotensinogen in hepatocytes contributes to Western diet-induced liver steatosis

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1. scibot 13 Jan 2020
  
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  RRID:AB_2137703
  
  DOI: 10.1194/jlr.M093252
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6889717/
Nov 2018
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Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-2-regulated apoptosis in pancreatic cancer cells

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1. scibot 05 Nov 2018
  
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tandfonline.com/doi/full/10.1080/15384047.2018.1504718
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Untitled document

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Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission

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Systematic Functional Annotation of Somatic Mutations in Cancer

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sciencedirect.com/science/article/pii/S1550413117306113
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Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy

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sciencedirect.com/science/article/pii/S153458071730953X
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Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity

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  AB_2137703
  
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academic.oup.com/endo/article/159/1/323/4411795
Nov 2017
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TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

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Systematic Characterization of Autophagy in Gestational Diabetes Mellitus

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  AB_2137703
  
  Curator: @patriciaelyse_
  
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academic.oup.com/endo/article/158/8/2522/3805448/Systematic-Characterization-of-Autophagy-in
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FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway

1
1. scibot 08 Nov 2017
  
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  AB_2137703
  
  Curator: @chewbeccax
  
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academic.oup.com/endo/article/158/7/2155/3819438/FoxO1-Promotes-Mitophagy-in-the-Podocytes-of
elifesciences.org elifesciences.org

Mitosis can drive cell cannibalism through entosis

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elifesciences.org/articles/27134
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Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy

1
1. scibot 08 Nov 2017
  
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  AB_2137703
  
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Contribution of Hippocampal 5-HT 3 Receptors in Hippocampal Autophagy and Extinction of Conditioned Fear Responses after a Single Prolonged Stress Exposure in Rats - Springer

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link.springer.com/article/10.1007/s10571-016-0395-7/fulltext.html

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