135 Matching Annotations
  1. Oct 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
    1
    1. scibot 05 Oct 2024
      RRID:AB_2137707

      DOI: 10.1016/j.chembiol.2023.06.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
    1
    1. scibot 26 Sep 2024
      RRID:AB_2137707

      DOI: 10.1016/j.isci.2024.110693

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
  5. www.sciencedirect.com www.sciencedirect.com
    ZIKV Induces P62-Mediated Autophagic Degradation of TRAF6 through TRAF6-NS1 Interaction
    2
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.isci.2024.110757

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    2. scibot 25 Sep 2024
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      DOI: 10.1016/j.isci.2024.110757

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    sciencedirect.com/science/article/pii/S2589004224019825
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114484

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    ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
  8. Jul 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.chembiol.2024.06.014

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    sciencedirect.com/science/article/pii/S2451945624002745
  10. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
    1
    1. scibot 04 Jul 2024
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      DOI: 10.7554/eLife.98649

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    elifesciences.org/articles/98649
  11. Jun 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.devcel.2024.04.020

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    sciencedirect.com/science/article/pii/S1534580724002958
  13. link.springer.com link.springer.com
    ATG16L1 induces the formation of phagophore-like membrane cups
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1038/s41594-024-01300-y

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    link.springer.com/article/10.1038/s41594-024-01300-y
  14. May 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
    1
    1. scibot 21 May 2024
      RRID:AB_2137707

      DOI: 10.1016/j.cmet.2024.04.018

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    sciencedirect.com/science/article/pii/S1550413124001384
  16. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
    1
    1. scibot 10 May 2024
      3868; Cell Signaling Technology

      DOI: 10.1101/2024.01.25.577280

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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  17. Apr 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
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    Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109580

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    sciencedirect.com/science/article/pii/S2589004224008022
  20. www.sciencedirect.com www.sciencedirect.com
    An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114020

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    sciencedirect.com/science/article/pii/S2211124724003486
  21. Feb 2024
  22. aacrjournals.org aacrjournals.org
    Phospholipase PLCE1 promotes transcription and phosphorylation of MCM7 to drive tumor progression in esophageal cancer
    1
    1. scibot 23 Feb 2024
      RRID:AB_2137707

      DOI: 10.1158/0008-5472.CAN-23-1633

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    aacrjournals.org/cancerres/article/84/4/560/734132/Phospholipase-PLCE1-Promotes-Transcription-and
  23. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    2
    1. scibot 08 Feb 2024
      RRID:AB_2137707

      DOI: 10.1016/j.molcel.2024.01.012

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      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838806/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EBAG9-deficient mice display decreased bone mineral density with suppressed autophagy
    1
    1. scibot 06 Feb 2024
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      DOI: 10.1016/j.isci.2024.108871

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    ncbi.nlm.nih.gov/pmc/articles/PMC10835455/
  26. Jan 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy
    1
    1. scibot 11 Jan 2024
      RRID:AB_2137707

      DOI: 10.1016/j.ebiom.2023.104961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10825369/
  28. Nov 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
    1
    1. scibot 18 Nov 2023
      RRID:AB_2137707

      DOI: 10.1016/j.isci.2023.108308

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    sciencedirect.com/science/article/pii/S2589004223023854
  30. www.sciencedirect.com www.sciencedirect.com
    ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress
    1
    1. scibot 17 Nov 2023
      RRID:AB_2137707

      DOI: 10.1016/j.celrep.2023.113402

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    sciencedirect.com/science/article/pii/S2211124723014146
  31. Oct 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modification of Lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression
    1
    1. scibot 21 Oct 2023
      RRID:AB_2137707

      DOI: 10.1016/j.isci.2023.108142

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    ncbi.nlm.nih.gov/pmc/articles/PMC10585400/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.112790

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528745/
  34. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1038/s41586-023-06657-6

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    52.53.155.43/0f3eb7b8d15ef36be47b7c18ecdf1d19ad34ca1a/s41586-023-06657-6_reference-html.html
  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    PARP1 inhibition protects mice against Japanese encephalitis virus infection
    1
    1. scibot 08 Sep 2023
      RRID:AB_2137707

      DOI: 10.1016/j.celrep.2023.113103

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    sciencedirect.com/science/article/pii/S2211124723011142
  37. Jul 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapamycin reverses ferroptosis by increasing autophagy in MPTP/MPP+-induced models of Parkinson’s disease
    1
    1. scibot 25 Jul 2023
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      DOI: 10.4103/1673-5374.371381

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    ncbi.nlm.nih.gov/pmc/articles/PMC10360095/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bexarotene improves motor function after spinal cord injury in mice
    1
    1. scibot 22 Jul 2023
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      DOI: 10.4103/1673-5374.373676

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    ncbi.nlm.nih.gov/pmc/articles/PMC10358692/
  40. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112807

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    sciencedirect.com/science/article/pii/S2211124723008185
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
    1
    1. scibot 08 Jul 2023
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      DOI: 10.1158/0008-5472.CAN-22-3450

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    ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
  42. Jun 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
    1
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      DOI: 10.1016/j.celrep.2023.112693

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    sciencedirect.com/science/article/pii/S2211124723007040
  44. 52.53.155.43 52.53.155.43
    can-22-3450-html.html
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  45. May 2023
  46. www.sciencedirect.com www.sciencedirect.com
    DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons
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      DOI: 10.1016/j.celrep.2023.112575

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    sciencedirect.com/science/article/pii/S2211124723005867
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  48. pubs.acs.org pubs.acs.org
    The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
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      DOI: 10.1021/acsinfecdis.0c00349

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    pubs.acs.org/doi/full/10.1021/acsinfecdis.0c00349
  49. Apr 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation
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      DOI: 10.1016/j.cmet.2023.03.019

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    sciencedirect.com/science/article/pii/S1550413123001249
  51. Feb 2023
  52. www.sciencedirect.com www.sciencedirect.com
    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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      DOI: 10.1016/j.devcel.2023.01.006

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    sciencedirect.com/science/article/pii/S1534580723000370
  53. www.nature.com www.nature.com
    CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells
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    1. scibot 15 Feb 2023
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      DOI: 10.1038/s41598-023-29437-8

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    nature.com/articles/s41598-023-29437-8
  54. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
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      DOI: 10.1016/j.isci.2023.105965

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    sciencedirect.com/science/article/pii/S2589004223000421
  55. www.sciencedirect.com www.sciencedirect.com
    β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence
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      DOI: 10.1016/j.mito.2022.12.004

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    sciencedirect.com/science/article/pii/S1567724922001088
  56. Dec 2022
  57. www.sciencedirect.com www.sciencedirect.com
    The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER
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  58. Nov 2022
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    Autophagy promotes cell survival by maintaining NAD levels
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  60. Oct 2022
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    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
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  62. Sep 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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  64. Aug 2022
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    Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
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  66. Jul 2022
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    Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation
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  68. Jun 2022
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    The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity
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    miR-4463 Regulates Hypoxia-Induced Autophagy and Apoptosis by Targeting ULK1 in Endothelial Cells
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  71. May 2022
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    MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1
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    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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  74. Apr 2022
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    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control
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  77. Mar 2022
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    A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis
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  79. Jan 2022
  80. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis
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  81. Dec 2021
  82. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    A novel live-cell imaging assay reveals regulation of endosome maturation
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  85. Oct 2021
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    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
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    Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
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  88. Sep 2021
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    Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver
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  90. Aug 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells
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  92. www.cell.com www.cell.com
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  98. Jul 2021
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    SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance
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    Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats
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    Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment
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      rabbit polyclonal anti-LC3B

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      Anti-LC3B

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  103. www.nature.com www.nature.com
    MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
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  104. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A role for autophagy in long‐term spatial memory formation in male rodents
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    Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD
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    NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism
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  107. pubs.acs.org pubs.acs.org
    The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
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      DOI: 10.1021/acsinfecdis.0c00349

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  108. Jun 2021
  109. www.sciencedirect.com www.sciencedirect.com
    LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes
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    Oncogene-regulated release of extracellular vesicles
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  111. May 2021
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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      DOI: 10.1016/j.molcel.2020.10.018

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    NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
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    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
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    Autophagy blockade limits HER2+ breast cancer tumorigenesis by perturbing HER2 trafficking and promoting release via small extracellular vesicles
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    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
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  127. Nov 2020
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  130. Sep 2020
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    Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery
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    Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34
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    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
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    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
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    Mitophagy, Autophagy and Cell Death: The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death
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  142. Jan 2020
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    Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells
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    LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion
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    KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis
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    PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
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    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
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    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
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    Curcumin Attenuates gp120-Induced Microglial Inflammation by Inhibiting Autophagy via the PI3K Pathway
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    AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
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    Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors
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    Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
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    Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria
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    Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1
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    Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy
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    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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    Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells
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    CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
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    MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
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    Modulation of Autophagy by BDNF Underlies Synaptic Plasticity
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    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
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    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
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    Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks
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    Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
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