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    2025.08.28.672784v1.full-html.html
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  3. Aug 2025
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    Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS
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    Sustained neuronal DNA damage and PARP activation lead to VEGFA-mediated blood-brain barrier disruption in radiation-induced brain injury
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  7. Jul 2025
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    Transplantation of human neural stem cells repairs neural circuits and restores neurological function in the stroke-injured brain
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    G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation
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  12. Jun 2025
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    A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration
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    The human neural cell atlas of Zika virus infection in developing brain tissue
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    CacyBP/SIP Protein Regulates the Length and Branching of Neuronal Processes During Cortical Development
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  17. May 2025
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    Polyunsaturated fatty acids in lipid membranes regulate human neuronal function and amyloid-β production
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    m6A RNA methylation-mediated control of global APC expression is required for local translation of β-actin and axon development
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    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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    Generation of an induced pluripotent stem cell (iPSC) line carrying a KCNA2 homozygous (p.Arg294His, R294H) mutation related to hereditary spastic paraplegia
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  22. Apr 2025
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    Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis
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  28. Mar 2025
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    Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease
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  32. Feb 2025
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    Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation
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    Dab1 expression level controls Reelin-induced PI3K-Akt activation in early GABAergic neurons
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    Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
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  37. Jan 2025
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    A multifunctional sensor for cell traction force, matrix remodeling and biomechanical assays in self-assembled 3D tissues in vitro
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  41. Dec 2024
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    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytes
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  51. Nov 2024
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    Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
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  56. Oct 2024
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    The chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin
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  58. Sep 2024
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  62. Aug 2024
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    Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy
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  65. Jul 2024
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    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    A three-dimensional tissue-engineered rostral migratory stream as an in vitro platform for subventricular zone-derived cell migration
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  70. Jun 2024
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    TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
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  73. May 2024
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    Distinct Alterations of Dendritic Spine Morphology in the Absence of β-Neurexins
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    Effect of M694V mutation in the MEFV gene, associated with Familial Mediterranean fever, on the morphology of iPSC-derived macrophages
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    Nr4a1 regulates cell-specific transcriptional programs in inhibitory GABAergic interneurons
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    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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  80. Apr 2024
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    Generation of human cerebral organoids with a structured outer subventricular zone
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
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    Protocol to encapsulate cerebral organoids with alginate hydrogel shell to induce volumetric compression
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  85. Mar 2024
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    Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway
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    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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    Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation
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    Alternative splicing decouples local from global PRC2 activity
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    Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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  93. Feb 2024
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  98. Jan 2024
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    Distinct Alterations in Dendritic Spine Morphology in the Absence of β-Neurexins
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    Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation
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  114. Oct 2023
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    Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis
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  144. May 2023
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    Spatially Resolved Proteomic Profiling Uncovers Structural and Functional Regulators of the Axon Initial Segment
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  148. Apr 2023
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  156. Feb 2023
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  162. Jan 2023
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  170. Nov 2022
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  190. Jun 2022
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  195. Apr 2022
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  199. Mar 2022
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    Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1G93A Mice Reveals Widespread Loss of Androgen Receptor Occurring Early in Spinal Motor Neurons
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  204. Feb 2022
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  207. Jan 2022
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  212. Dec 2021
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