74 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    2025.09.03.673267v1.full-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12697282/
  3. Dec 2025
  4. link.springer.com link.springer.com
    Endoplasmic Reticulum Stress Mediates Axon Initial Segment Shortening: Implications for Diabetic Brain Complications
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    link.springer.com/article/10.1007/s12031-025-02448-y
  5. Nov 2025
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    Human iPSC-Derived Microglia Integrate Into Cerebral Organoids and Assume an In Vivo-Like Phenotype
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    pmc.ncbi.nlm.nih.gov/articles/PMC12606696/
  7. Oct 2025
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    Hide-and-Seek genome editing reveals that Gephyrin is required for axo-axonic synapse assembly
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    pnas.org/doi/abs/10.1073/pnas.2500726122
  9. Sep 2025
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    Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down syndrome
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    sciencedirect.com/science/article/pii/S221112472501071X
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    2025.09.03.673267v1.full-html.html
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  12. Feb 2025
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    TRIM46 is required for microtubule fasciculation in vivo but not axon specification or axon initial segment formation
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    jneurosci.org/content/44/42/e0976242024
  14. Sep 2024
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    RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages
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    sciencedirect.com/science/article/pii/S1097276524007007
  16. Aug 2024
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    CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids
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    sciencedirect.com/science/article/pii/S2589004224018388
  18. rupress.org rupress.org
    An evolutionarily conserved AnkyrinG-dependent motif clusters axonal K2P K+ channels
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    rupress.org/jcb/article/223/10/e202401140/276880/An-evolutionarily-conserved-AnkyrinG-dependent
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    Epileptic Encephalopathy Caused by Mutations in the Guanine Nucleotide Exchange Factor DENND5A
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    cell.com/ajhg/pdfExtended/S0002-9297(16)30442-6
  20. May 2024
  21. www.biorxiv.org www.biorxiv.org
    TRIM46 is not required for axon specification or axon initial segment formation in vivo
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    biorxiv.org/content/10.1101/2024.05.23.595556v1
  22. Oct 2023
  23. www.nature.com www.nature.com
    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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    nature.com/articles/s41467-023-42273-8
  24. Aug 2023
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    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0896627323005135
  26. Jun 2023
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    “Disruption of Golgi markers by two RILP-directed shRNAs in neurons: a new role for RILP or a neuron-specific off-target phenotype?”
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    sciencedirect.com/science/article/pii/S0021925823019440
  28. May 2023
  29. 52.53.155.43 52.53.155.43
    “Disruption of Golgi markers by two RILP-directed shRNAs in neurons: a new role for RILP or a neuron-specific off-target phenotype?”
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    52.53.155.43/c602035c32bd2fdddc6170f21c8c320c533a7422/2023.03.08.531742v1.full-html.html
  30. 52.53.155.43 52.53.155.43
    Spatially Resolved Proteomic Profiling Uncovers Structural and Functional Regulators of the Axon Initial Segment
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    52.53.155.43/1b0cedf04512903e90b9ef1858ffefd94df1235f/2023.03.06.531334v1.full-html.html
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    Methods for culturing adult CNS neurons reveal a CNS conditioning effect
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    sciencedirect.com/science/article/pii/S266723752200128X
  32. Apr 2023
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    Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation
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    sciencedirect.com/science/article/pii/S0896627323000375
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    Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028829/
  36. Mar 2023
  37. www.sciencedirect.com www.sciencedirect.com
    A non-hallucinogenic LSD analog with therapeutic potential for mood disorders
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    sciencedirect.com/science/article/pii/S2211124723002140
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    Sympathetic neurons secrete retrogradely transported TrkA on extracellular vesicles
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    link.springer.com/article/10.1038/s41598-023-30728-3
  39. Sep 2022
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling
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    ncbi.nlm.nih.gov/pmc/articles/PMC9462691/
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    Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson’s associated GBA gene
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    sciencedirect.com/science/article/pii/S1873506122002689
  42. Jun 2022
  43. www.jneurosci.org www.jneurosci.org
    Dynein is required for Rab7-dependent endosome maturation, retrograde dendritic transport, and degradation
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    jneurosci.org/content/42/22/4415
  44. May 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing
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    sciencedirect.com/science/article/pii/S1873506122001556
  46. Mar 2022
  47. www.jneurosci.org www.jneurosci.org
    Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD
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    jneurosci.org/content/42/9/1666
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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    sciencedirect.com/science/article/pii/S0092867421012320
  50. Oct 2021
  51. www.eneuro.org www.eneuro.org
    The type 2 diabetes factor methylglyoxal mediates axon initial segment shortening and alters neuronal function at the cellular and network levels
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    eneuro.org/content/8/5/ENEURO.0201-21.2021
  52. Aug 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interaction and Subcellular Association of PRRT1/SynDIG4 With AMPA Receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8365426/
  54. jcb.rupress.org jcb.rupress.org
    Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes
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    jcb.rupress.org/content/217/9/3141
  55. www.sciencedirect.com www.sciencedirect.com
    Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization
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    sciencedirect.com/science/article/pii/S0306452217304967
  56. www.molbiolcell.org www.molbiolcell.org
    Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels
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    molbiolcell.org/doi/abs/10.1091/mbc.E18-05-0337
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6233057/
  58. Jul 2021
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo
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    onlinelibrary.wiley.com/doi/10.1002/cne.24168/full
  60. www.jbc.org www.jbc.org
    Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND “OFF-PATHWAY” CELLULAR MECHANISMS
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  61. May 2021
  62. www.sciencedirect.com www.sciencedirect.com
    NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
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    sciencedirect.com/science/article/pii/S1534580720309254
  63. Mar 2021
  64. jcs.biologists.org jcs.biologists.org
    Endogenously expressed Ranbp2 is not at the axon initial segment
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    jcs.biologists.org/content/134/6/jcs256180
  65. www.embopress.org www.embopress.org
    CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway
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    embopress.org/doi/abs/10.15252/embr.202051349
  66. Sep 2020
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β spectrin-dependent and domain specific mechanisms for Na+ channel clustering
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    ncbi.nlm.nih.gov/pmc/articles/PMC7237202/
  68. rupress.org rupress.org
    NuMA1 promotes axon initial segment assembly through inhibition of endocytosis
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    rupress.org/jcb/article/219/2/e201907048/132495/NuMA1-promotes-axon-initial-segment-assembly
  69. elifesciences.org elifesciences.org
    Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum
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    elifesciences.org/articles/54443
  70. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein
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    pubmed.ncbi.nlm.nih.gov/32900375/
  71. www.cell.com www.cell.com
    Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype
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    cell.com/cell-reports/abstract/S2211-1247(18)31477-3
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC6984820/
  73. www.molbiolcell.org www.molbiolcell.org
    Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels | Molecular Biology of the Cell
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    molbiolcell.org/doi/10.1091/mbc.E18-05-0337
  74. Jan 2020
  75. www.nature.com www.nature.com
    Mapping axon initial segment structure and function by multiplexed proximity biotinylation
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    nature.com/articles/s41467-019-13658-5
  76. www.sciencedirect.com www.sciencedirect.com
    Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons
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    sciencedirect.com/science/article/pii/S2211124719313300
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    A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons
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    sciencedirect.com/science/article/pii/S0165027019304352
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    Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
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    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
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  81. Nov 2018
  82. www.sciencedirect.com www.sciencedirect.com
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    βIV Spectrinopathies Cause Profound Intellectual Disability, Congenital Hypotonia, and Motor Axonal Neuropathy
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    sciencedirect.com/science/article/pii/S0002929718301599
  84. www.jneurosci.org www.jneurosci.org
    Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain
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    jneurosci.org/content/38/20/4774
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    Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment
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    sciencedirect.com/science/article/pii/S089662731731187X
  86. www.nature.com www.nature.com
    MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling
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    nature.com/articles/mp201786
  87. Nov 2017
  88. www.karger.com www.karger.com
    WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene TCF4
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    karger.com/Article/FullText/475666
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    The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes
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    nature.com/articles/s41598-017-07667-x
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    Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization
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    sciencedirect.com/science/article/pii/S0306452217304967
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    Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses
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    jneurosci.org/content/37/5/1062
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    Histones facilitate α-synuclein aggregation during neuronal apoptosis
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    link.springer.com/article/10.1007/s00401-016-1660-z
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    Identification of diverse astrocyte populations and their malignant analogs
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    nature.com/neuro/journal/v20/n3/full/nn.4493.html
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    Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms - ScienceDirect
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    sciencedirect.com/science/article/pii/S0378874116306705
  95. www.cell.com www.cell.com
    Epileptic Encephalopathy Caused by Mutations in the Guanine Nucleotide Exchange Factor DENND5A
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    cell.com/ajhg/pdfExtended/S0002-9297(16)30442-6
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental Changes in Expression of βIV Spectrin Splice Variants at Axon Initial Segments and Nodes of Ranvier
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    ncbi.nlm.nih.gov/pmc/articles/PMC5226651/
  97. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity
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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-016-0403-7
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    Pikuni-Blackfeet traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson’s disease-related symptoms - ScienceDirect
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  99. Local file Local file
    Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides
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  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo
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    onlinelibrary.wiley.com/doi/10.1002/cne.24168/full
  101. www.sciencedirect.com www.sciencedirect.com
    Editing DNA Methylation in the Mammalian Genome
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