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Butyrolactone I from Aspergillus fungi blocks neutrophil FPR1 to alleviate acute respiratory distress syndrome

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.bcp.2025.117348
  
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sciencedirect.com/science/article/pii/S0006295225006136
Jul 2025
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TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115972
  
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cell.com/cell-reports/abstract/S2211-1247(25)00743-0
Jun 2025
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Piezo1 senses hyphae and initiates host defense against pathogenic fungi

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115839
  
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sciencedirect.com/science/article/pii/S2211124725006102
May 2025
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A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection

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1. scibot 19 May 2025
  
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  DOI: 10.1038/s44318-025-00412-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12048508/
Apr 2025
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SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115588
  
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sciencedirect.com/science/article/pii/S2211124725003596
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PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115541
  
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sciencedirect.com/science/article/pii/S2211124725003122
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Scutellaria barbata ameliorates acute respiratory distress syndrome by inhibiting neutrophil-mediated inflammatory responses

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.jep.2025.119653
  
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sciencedirect.com/science/article/pii/S037887412500337X
Mar 2025
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ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity

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1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115397
  
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sciencedirect.com/science/article/pii/S2211124725001688
Dec 2024
aacrjournals.org aacrjournals.org

Nuclear Focal Adhesion Kinase Protects Against Cisplatin Stress in Ovarian Carcinoma

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1. scibot 24 Dec 2024
  
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  DOI: 10.1158/2767-9764.CRC-24-0382
  
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aacrjournals.org/cancerrescommun/article/4/12/3165/750609/Nuclear-Focal-Adhesion-Kinase-Protects-against
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The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.10.044
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
Aug 2024
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Epitranscriptomic reader YTHDF2 regulates SEK1(MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress

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1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110619
  
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sciencedirect.com/science/article/pii/S2589004224018443
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The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114608
  
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sciencedirect.com/science/article/pii/S2211124724009586
Jul 2024
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Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.chembiol.2024.06.014
  
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sciencedirect.com/science/article/pii/S2451945624002745
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RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.molcel.2024.06.023
  
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sciencedirect.com/science/article/pii/S1097276524005306
Apr 2024
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Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome

2
1. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.jare.2024.03.019
  
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2. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.jare.2024.03.019
  
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sciencedirect.com/science/article/pii/S209012322400119X
Mar 2024
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Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113929
  
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2. scibot 08 Mar 2024
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.celrep.2024.113929
  
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sciencedirect.com/science/article/pii/S2211124724002572
Feb 2024
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EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

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1. scibot 09 Feb 2024
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.celrep.2024.113714
  
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sciencedirect.com/science/article/pii/S2211124724000421
Dec 2023
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113560
  
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sciencedirect.com/science/article/pii/S2211124723015723
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis

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1. scibot 16 Nov 2023
  
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  DOI: 10.1186/s12885-023-11612-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10644579/
Jun 2023
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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.06.002
  
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sciencedirect.com/science/article/pii/S1074761323002376
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BPS Publications

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1. scibot 01 Jun 2023
  
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  DOI: 10.1111/bph.16080
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
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Targeting formyl peptide receptor 1 by anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome

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1. scibot 01 Jun 2023
  
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  DOI: 10.1111/bph.16073
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16073
Apr 2023
www.biorxiv.org www.biorxiv.org

ANKRD49 promotes the metastasis of NCI-H1299 and NCI-H1703 cells via activating JNK-ATF2/c-Jun-MMP-2/9 axis

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1. scibot 28 Apr 2023
  
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  RRID:AB_2141027
  
  DOI: 10.1101/2023.03.22.533821
  
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biorxiv.org/content/10.1101/2023.03.22.533821v1
Feb 2023
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Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.cmet.2023.01.011
  
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sciencedirect.com/science/article/pii/S1550413123000116
Nov 2022
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Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells

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1. scibot 30 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111744
  
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sciencedirect.com/science/article/pii/S2211124722016229
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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

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1. scibot 17 Nov 2022
  
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  DOI: 10.1016/j.cmet.2022.10.011
  
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sciencedirect.com/science/article/pii/S1550413122004892
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Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis

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1. scibot 05 Nov 2022
  
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  DOI: 10.1016/j.ebiom.2022.104312
  
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sciencedirect.com/science/article/pii/S2352396422004947
Aug 2022
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STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization

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1. scibot 30 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104923
  
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sciencedirect.com/science/article/pii/S2589004222011956
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Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development

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1. scibot 10 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111178
  
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sciencedirect.com/science/article/pii/S2211124722009913
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Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway

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1. scibot 06 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111158
  
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sciencedirect.com/science/article/pii/S2211124722009676
Jul 2022
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Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.yexmp.2022.104814
  
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sciencedirect.com/science/article/pii/S0014480022000776
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs

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1. scibot 28 Oct 2021
  
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  DOI: 10.3389/fphar.2021.674095
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8545060/
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Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity

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1. scibot 23 Oct 2021
  
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  DOI: 10.1111/bph.15597
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8518616/
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Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains

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1. scibot 06 Oct 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.celrep.2021.109777
  
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sciencedirect.com/science/article/pii/S2211124721012316
Sep 2021
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Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns

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1. scibot 14 Sep 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.chembiol.2021.07.015
  
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sciencedirect.com/science/article/pii/S245194562100355X
Aug 2021
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Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

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1. scibot 14 Aug 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1210/en.2019-00177
  
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academic.oup.com/endo/article/160/11/2692/5551999
Jul 2021
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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity

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1. scibot 31 Jul 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.chom.2018.11.001
  
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sciencedirect.com/science/article/pii/S1931312818305584
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Untitled document

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1. scibot 27 Jul 2021
  
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  AB_2141027
  
  DOI: 10.1210/en.2017-00029
  
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  Curator: @evieth
  
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academic.oup.com/endo/article/158/10/3281/3885816
Jun 2021
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Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation

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1. scibot 23 Jun 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.celrep.2021.109272
  
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sciencedirect.com/science/article/pii/S2211124721006392
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Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1

1
1. scibot 19 Jun 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.cmet.2021.05.019
  
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sciencedirect.com/science/article/pii/S1550413121002709
May 2021
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Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model

1
1. scibot 09 May 2021
  
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  AB_2141027
  
  DOI: 10.1016/j.phymed.2020.153324
  
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sciencedirect.com/science/article/pii/S0944711320301562
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Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation

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1. scibot 08 May 2021
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.molcel.2020.10.026
  
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sciencedirect.com/science/article/pii/S1097276520307334
Sep 2020
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TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation

1
1. scibot 15 Sep 2020
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.cmet.2020.03.007
  
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  RRID:AB_2141027 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413120301224
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DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

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1. scibot 09 Sep 2020
  
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  RRID:AB_2141027
  
  DOI: 10.1210/endocr/bqaa139
  
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academic.oup.com/endo/article/161/10/bqaa139/5892311
Jan 2020
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The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

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1. scibot 13 Jan 2020
  
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  RRID:AB_2141027
  
  DOI: 10.1016/j.cell.2019.05.035
  
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sciencedirect.com/science/article/pii/S009286741930563X
Nov 2017
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IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells

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1. scibot 08 Nov 2017
  
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  AB_2141027
  
  Curator: @patriciaelyse_
  
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academic.oup.com/endo/article/158/10/3281/3885816/IL-1-Upregulates-StAR-and-Progesterone-Production