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55 Matching Annotations

Oct 2025
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Multi-layer stratified oncology platform utilizing transcriptomics, prostate cancer organoids, and modeling of drug response

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1. scibot 21 Oct 2025
  
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  DOI: 10.1186/s13046-025-03540-2
  
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link.springer.com/article/10.1186/s13046-025-03540-2
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mucin 5AC promotes breast cancer brain metastasis through cMET/CD44v6

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1. scibot 07 Sep 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-1977
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11882111/
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Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET

1
1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102335
  
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sciencedirect.com/science/article/pii/S2666379125004082
Jun 2025
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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.chembiol.2025.05.005
  
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sciencedirect.com/science/article/pii/S2451945625001667
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 19 Apr 2025
  
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  DOI: 10.1158/1535-7163.mct-24-0756
  
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52.53.155.43/a9bdac937b5d56e963502c7a9aeebc7cca17a770/PDF-html.html
Jan 2025
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The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC

1
1. scibot 28 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2025.101929
  
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sciencedirect.com/science/article/pii/S2666379125000023
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits

1
1. scibot 11 Dec 2024
  
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  RRID:AB_2143884
  
  DOI: 10.4103/NRR.NRR-D-23-01471
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11624886/
Sep 2024
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Anti-HDGF antibody targets EGFR tyrosine kinase inhibitor-tolerant cells in NSCLC patient-derived xenografts

1
1. scibot 05 Sep 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1158/2767-9764.CRC-24-0020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11370239/
Aug 2024
www.nature.com www.nature.com

LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration

1
1. scibot 23 Aug 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1038/s42255-024-01110-y
  
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nature.com/articles/s42255-024-01110-y
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E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network

1
1. scibot 01 Aug 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1158/2767-9764.CRC-23-0370
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11288008/
Jul 2024
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A cyclic peptide-grafted Fc with hepatocyte growth factor functionality ameliorates hepatic fibrosis in a non-alcoholic steatohepatitis mouse model

1
1. scibot 19 Jul 2024
  
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  AB_2143884
  
  DOI: 10.1016/j.isci.2024.110426
  
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sciencedirect.com/science/article/pii/S2589004224016511
May 2024
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Ovulation provides excessive coagulation and hepatocyte growth factor signals to cause postoperative intraabdominal adhesions

1
1. scibot 23 May 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.isci.2024.109788
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11103365/
Mar 2024
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Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion

1
1. scibot 28 Mar 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2024.114002
  
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sciencedirect.com/science/article/pii/S2211124724003309
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer

2
1. scibot 11 Feb 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1158/2767-9764.CRC-23-0321
  
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2. scibot 11 Feb 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1158/2767-9764.CRC-23-0321
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10851855/
Jan 2024
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Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer

1
1. scibot 23 Jan 2024
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.xcrm.2023.101388
  
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sciencedirect.com/science/article/pii/S2666379123006171
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms

1
1. scibot 07 Sep 2023
  
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  AB_2143884
  
  DOI: 10.1158/1078-0432.CCR-22-1763
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9992133/
Jun 2023
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A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth

1
1. scibot 27 Jun 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2023.112688
  
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sciencedirect.com/science/article/pii/S221112472300699X
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Overcoming MET-mediated resistance in oncogene-driven NSCLC

1
1. scibot 23 Jun 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.isci.2023.107006
  
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sciencedirect.com/science/article/pii/S2589004223010830
May 2023
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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

1
1. scibot 05 May 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2022.111077
  
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sciencedirect.com/science/article/pii/S2211124722008750
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IL-6–GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models

1
1. scibot 20 Apr 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1126/sciadv.adf4490
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10104468/
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IL-6–GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models

2
1. scibot 19 Apr 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1126/sciadv.adf4490
  
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2. scibot 19 Apr 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1126/sciadv.adf4490
  
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science.org/doi/10.1126/sciadv.adf4490
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Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer

1
1. scibot 18 Apr 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1038/s41416-023-02264-4
  
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nature.com/articles/s41416-023-02264-4
Mar 2023
52.53.155.43 52.53.155.43

943-html.html

1
1. scibot 16 Mar 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1158/1078-0432.CCR-22-1763
  
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52.53.155.43/c8f103b982e67ed0e9f7f2acbda462e2c6f6fa27/943-html.html
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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis

1
1. scibot 02 Mar 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2023.112164
  
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sciencedirect.com/science/article/pii/S2211124723001754
Feb 2023
52.53.155.43 52.53.155.43

The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in human kidney

1
1. scibot 03 Feb 2023
  
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  RRID:AB_2143884
  
  DOI: 10.1152/ajprenal.00196.2022
  
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52.53.155.43/a528a4dac399b148cd4f23f30162887ff89bf871/ajprenal.00196.2022-html.html
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EZH2/hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression

1
1. scibot 11 Jan 2023
  
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  RRID:AB_2143884
  
  DOI: 10.7554/eLife.79432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9829410/
Dec 2022
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Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes

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1. scibot 17 Dec 2022
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.ebiom.2022.104410
  
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sciencedirect.com/science/article/pii/S2352396422005928
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer

1
1. scibot 18 Nov 2022
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.isci.2022.105419
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9646953/
Sep 2022
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A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration

1
1. scibot 29 Sep 2022
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.devcel.2022.09.003
  
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sciencedirect.com/science/article/pii/S1534580722006335
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Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma

1
1. scibot 21 Sep 2022
  
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  RRID:mAb#3077
  
  DOI: 10.1016/j.xcrm.2022.100659
  
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sciencedirect.com/science/article/pii/S2666379122001914
Jul 2022
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Src activation in lipid rafts confers epithelial cells with invasive potential to escape from apical extrusion during cell competition

1
1. scibot 09 Jul 2022
  
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  RRID: 2143884
  
  DOI: 10.1016/j.cub.2022.06.038
  
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sciencedirect.com/science/article/pii/S0960982222010004
Apr 2022
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Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma

1
1. scibot 21 Apr 2022
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2022.110712
  
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sciencedirect.com/science/article/pii/S2211124722004739
Nov 2021
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De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

1
1. scibot 09 Nov 2021
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.isci.2021.103302
  
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sciencedirect.com/science/article/pii/S2589004221012712
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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

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1. scibot 03 Nov 2021
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2021.109957
  
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sciencedirect.com/science/article/pii/S2211124721014340
Oct 2021
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A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

1
1. scibot 23 Oct 2021
  
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  RRID:AB_2143884
  
  DOI: 10.7554/eLife.70885
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8516413/
Aug 2021
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Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

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1. scibot 09 Aug 2021
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.devcel.2018.10.026
  
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sciencedirect.com/science/article/pii/S1534580718308803
Jul 2021
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Identification of candidates for driver oncogenes in scirrhous‐type gastric cancer cell lines

1
1. scibot 29 Jul 2021
  
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  phosphorylated MET
  
  DOI: 10.1111/cas.14111
  
  Resource: (Cell Signaling Technology Cat# 3077, RRID:AB_2143884)
  
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onlinelibrary.wiley.com/doi/full/10.1111/cas.14111
Apr 2021
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Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

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1. scibot 23 Apr 2021
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.cell.2020.02.003
  
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sciencedirect.com/science/article/pii/S0092867420301471
Oct 2020
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Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles

1
1. scibot 20 Oct 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2020.108261
  
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sciencedirect.com/science/article/pii/S221112472031250X
Sep 2020
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Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC

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1. scibot 26 Sep 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2020.107568
  
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sciencedirect.com/science/article/pii/S2211124720305179
Jan 2020
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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2019.07.021
  
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TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2019.07.086
  
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LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2019.11.063
  
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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

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1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.cmet.2019.06.014
  
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sciencedirect.com/science/article/pii/S1550413119303171
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LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2315156
  
  DOI: 10.1016/j.cell.2019.07.021
  
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Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.chembiol.2019.06.003
  
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sciencedirect.com/science/article/pii/S2451945619302041
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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2019.08.090
  
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sciencedirect.com/science/article/pii/S2211124719311520
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.celrep.2018.12.013
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124718319247
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2143884
  
  DOI: 10.1016/j.cmet.2019.01.002
  
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sciencedirect.com/science/article/pii/S1550413119300026
Nov 2018
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Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2143884
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0092867418312509
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Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

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1. scibot 05 Nov 2018
  
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  RRID:AB_2143884
  
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sciencedirect.com/science/article/pii/S1074761317304235
Nov 2017
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Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases

1
1. scibot 08 Nov 2017
  
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  AB_2143884
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S0969212617301338
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RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma

1
1. scibot 08 Nov 2017
  
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  AB_2143884
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S1535610817301575