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High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

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sciencedirect.com/science/article/pii/S2667237526003176
Aug 2026
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Excess intracellular lactate represses mRNA translation and tumor progression through lactate-tRNA charging

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TIMELESS promotes glioma stemness and malignancy through JAK-STAT3 pathway

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sciencedirect.com/science/article/pii/S0021925826023197
Jul 2026
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Troxerutin suppresses the stemness of hepatocellular carcinoma via the Syk/FOXO3 feedback loop

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  DOI: 10.1007/s10565-026-10194-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13319154/
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BPS Publications

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  DOI: 10.1111/bph.70528
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70528
Jun 2026
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STRAP promotes hepatocellular carcinoma progression through activation of an STRAP/Wnt-β-catenin/STRAP positive feedback loop

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  DOI: 10.1016/j.isci.2026.116377
  
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Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling

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pmc.ncbi.nlm.nih.gov/articles/PMC13198297/
May 2026
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Hepatic SNHG9 links gut microbiota to liver protection in drug-induced liver injury

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  DOI: 10.1038/s41467-026-73309-4
  
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nature.com/articles/s41467-026-73309-4
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ESM1 drives cisplatin resistance and ferroptosis resistance via ERBB2/FAK/SRC/HSPB1/NF-κB signaling in ovarian cancer

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sciencedirect.com/science/article/pii/S2589004226013520
Apr 2026
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USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma

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sciencedirect.com/science/article/pii/S2211124726004067
Mar 2026
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CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression

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1-s2.0-S2589004226007479-main-html.html

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54.241.53.176/e72524355eb321529f4dd9a65278a0820d03292a/1-s2.0-S2589004226007479-main-html.html
Feb 2026
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Streptococcus anginosus-generated succinate promotes the progression of gastric cancer via the succinate/SUCNR1/ABRAXAS1 axis

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1. scibot 27 Feb 2026
  
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1-s2.0-S2589004226003950-main-html.html

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54.241.53.176/59b9d8a5c8a63eb746e2777c0ebfdbb7d2ebe10f/1-s2.0-S2589004226003950-main-html.html
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1-s2.0-S2589004226002919-main-html.html

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pmc.ncbi.nlm.nih.gov/articles/PMC12936848/
Jan 2026
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Repression of Polycomb Group Factor 1 Inhibits EMT Progression in Colon Cancers Cells via Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathway

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1. scibot 06 Jan 2026
  
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  DOI: 10.1007/s10620-025-09641-4
  
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link.springer.com/article/10.1007/s10620-025-09641-4
Dec 2025
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A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

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1. scibot 23 Dec 2025
  
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  DOI: 10.64898/2025.12.18.695023
  
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54.241.53.176/4017c0bf441a0c93b25bb7d3207bac083a93d59a/2025.12.18.695023v1.full-html.html
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CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis

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  DOI: 10.3389/fonc.2025.1671797
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12672324/
Oct 2025
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Obesity induced by a high-fat diet regulates the MYC‒PPIL1 network in the mediation of asthenozoospermia

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pmc.ncbi.nlm.nih.gov/articles/PMC12512847/
Sep 2025
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HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer

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Aug 2025
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Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex

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Jun 2025
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PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity

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May 2025
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1-s2.0-S2589004225008958-main-html.html

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52.53.155.43/3124e289592a3629f97e02aa5117cdb2659dc765/1-s2.0-S2589004225008958-main-html.html
Apr 2025
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LINC02167 stabilizes KSR1 mRNA in an m5C-dependent manner to regulate the ERK/MAPK signaling pathway and promotes colorectal cancer metastasis

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  DOI: 10.1186/s13046-025-03368-w
  
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link.springer.com/article/10.1186/s13046-025-03368-w
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PRMT5-mediated methylation of METTL3 promotes cisplatin resistance in ovarian cancer by facilitating DNA repair mechanisms

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cell.com/cell-reports/fulltext/S2211-1247(25)00255-4
Mar 2025
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ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

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  DOI: 10.7554/eLife.101973
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
Dec 2024
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The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release

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Nov 2024
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Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis

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Sep 2024
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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Aug 2024
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Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT

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  DOI: 10.1186/s40170-024-00352-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11304919/
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FEBS Press

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  DOI: 10.1111/febs.16877
  
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52.53.155.43/64ced1d526c8a3e3d4ab74d77899078a022462a0/The FEBS Journal - 2023 - Shan - Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing-html.html
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Targeting tumor hypoxia inhibits aggressive phenotype of dedifferentiated thyroid cancer

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1. scibot 02 Aug 2024
  
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  DOI: 10.1210/clinem/dgac548
  
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academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgac548/6747527
Jul 2024
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Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation

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  DOI: 10.1016/j.cmet.2024.05.016
  
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Apr 2024
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Repurposing AS1411 for constructing ANM-PROTACs

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  DOI: 10.1016/j.chembiol.2024.03.011
  
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Genetic interactions reveal distinct biological and therapeutic implications in breast cancer

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A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice

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A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

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ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer

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IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner

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Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness

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can-23-0067-html.html

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Jun 2023
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FEBS Press

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52.53.155.43/64ced1d526c8a3e3d4ab74d77899078a022462a0/The FEBS Journal - 2023 - Shan - Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing-html.html
Oct 2022
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Targeting tumor hypoxia inhibits aggressive phenotype of dedifferentiated thyroid cancer

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Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration

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Nov 2021
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Efferocytosis induces macrophage proliferation to help resolve tissue injury

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Oct 2021
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Cancer cell immune mimicry delineates onco-immunologic modulation

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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

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MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer

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  DOI: 10.1016/j.ebiom.2019.03.027
  
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