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Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders

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  DOI: 10.1016/j.cell.2026.06.013
  
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sciencedirect.com/science/article/pii/S0092867426007002
Jun 2026
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δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20

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1. scibot 23 Jun 2026
  
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  DOI: 10.64898/2026.05.12.724361
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13192610/
Apr 2026
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Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.03.040
  
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sciencedirect.com/science/article/pii/S0092867426003417
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2026.03.31.715540.full-html.html

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54.241.53.176/ec4b78a03fd8ae2278abd58167b609de502ea286/2026.03.31.715540.full-html.html
Mar 2026
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Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain

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  DOI: 10.1016/j.cell.2026.02.015
  
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sciencedirect.com/science/article/pii/S0092867426002229
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Retinoid-X-Receptor as a Mediator of Poststroke Recovery by Reversing Age-Associated Phenotypes of Microglia/Hematogenous Macrophages

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1. scibot 11 Mar 2026
  
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  DOI: 10.1523/JNEUROSCI.0248-25.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12424960/
Dec 2025
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Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptopathy in encephalitis

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  DOI: 10.1016/j.neuron.2025.11.006
  
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sciencedirect.com/science/article/pii/S0896627325008530
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Age- and cell-type-specific effects of histone variant H2BE in the brain

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1. scibot 11 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116655
  
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sciencedirect.com:5037/science/article/pii/S2211124725014275
Nov 2025
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Combined somatic mutation and transcriptome analysis reveals region-specific differences in clonal architecture in human cortex

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1. scibot 15 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116458
  
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sciencedirect.com/science/article/pii/S221112472501229X
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The brain neurovascular epigenome and its association with dementia

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  DOI: 10.1016/j.neuron.2025.10.001
  
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sciencedirect.com/science/article/pii/S0896627325007548
Oct 2025
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Spatial coding dysfunction and network instability in the aging medial entorhinal cortex

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1. scibot 07 Oct 2025
  
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  DOI: 10.1038/s41467-025-63229-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12494969/
Sep 2025
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Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome

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1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.neuron.2025.08.028
  
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sciencedirect.com/science/article/pii/S0896627325006634
Aug 2025
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the benefit of mineralocorticoid receptor blockade in the treatment of experimental autoimmune encephalomyelitis mice

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.jsbmb.2025.106844
  
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sciencedirect.com/science/article/pii/S0960076025001724
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Age-dependent effect of environmental enrichment on the neural 3D chromatin interactome

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116182
  
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sciencedirect.com/science/article/pii/S2211124725009532
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Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment

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1. scibot 22 Aug 2025
  
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  DOI: 10.1038/s43587-025-00940-z
  
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nature.com/articles/s43587-025-00940-z
Jul 2025
www.biorxiv.org www.biorxiv.org

Repetitive Neuronal Activation Regulates Cellular Maturation State via Nuclear Reprogramming

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1. scibot 11 Jul 2025
  
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  DOI: 10.1101/2025.05.02.651848
  
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biorxiv.org/content/10.1101/2025.05.02.651848v3
May 2025
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Analgesic and neuroprotective effect of a lipid transfer protein isolated from Morinda citrifolia L. (noni) seeds on oxaliplatin-induced peripheral sensory neuropathy in mice

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1. scibot 16 May 2025
  
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  DOI: 10.1007/s00210-025-04216-6
  
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link.springer.com/article/10.1007/s00210-025-04216-6
Apr 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225006911-main-html.html

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1. scibot 17 Apr 2025
  
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  RRID:AB_2149209
  
  DOI: 10.1016/j.isci.2025.112430
  
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52.53.155.43/9030c799c07d6c73fd2245d204001a1cff44120f/1-s2.0-S2589004225006911-main-html.html
Mar 2025
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Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115454
  
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sciencedirect.com/science/article/pii/S2211124725002256
Feb 2025
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Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species

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  DOI: 10.1016/j.isci.2025.111820
  
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sciencedirect.com/science/article/pii/S258900422500080X
Sep 2024
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BPS Publications

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1. scibot 27 Sep 2024
  
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  DOI: 10.1111/bph.17318
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17318
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Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses

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1. scibot 27 Sep 2024
  
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  DOI: 10.1101/2024.08.28.610136
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11383992/
Aug 2024
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Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/jnr.23672
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23672/full
Jul 2024
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Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory

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1. scibot 26 Jul 2024
  
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  DOI: 10.1016/j.molcel.2024.06.025
  
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sciencedirect.com/science/article/pii/S109727652400532X
Jun 2024
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Intrathecal Fumagillin Alleviates Chronic Neuropathy-Induced Nociceptive Sensitization and Modulates Spinal Astrocyte-Neuronal Glycolytic and Angiogenic Proteins

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1. scibot 06 Jun 2024
  
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  DOI: 10.1007/s12035-024-04254-w
  
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link.springer.com/article/10.1007/s12035-024-04254-w
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Cell-type-specific effects of age and sex on human cortical neurons

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.neuron.2024.05.013
  
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sciencedirect.com/science/article/pii/S089662732400360X
May 2024
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Complementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior

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  DOI: 10.1016/j.xgen.2024.100545
  
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sciencedirect.com/science/article/pii/S2666979X24001010
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Spatial Coding Dysfunction and Network Instability in the Aging Medial Entorhinal Cortex

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1. scibot 03 May 2024
  
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  DOI: 10.1101/2024.04.12.588890
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11042240/
Mar 2024
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Epigenomic tomography for probing spatially defined chromatin state in the brain

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1. scibot 21 Mar 2024
  
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  DOI: 10.1016/j.crmeth.2024.100738
  
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sciencedirect.com/science/article/pii/S2667237524000638
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Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes

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  DOI: 10.1016/j.cell.2024.02.025
  
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  DOI: 10.1016/j.cell.2024.02.025
  
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sciencedirect.com/science/article/pii/S0092867424002277
Oct 2023
www.biorxiv.org www.biorxiv.org

MultipleXed Population Selection and Enrichment single nucleus RNA sequencing (XPoSE-seq) enables sample identity retention during transcriptional profiling of rare populations

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1. scibot 14 Oct 2023
  
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  DOI: 10.1101/2023.09.27.559834
  
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biorxiv.org/content/10.1101/2023.09.27.559834v1
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Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113187
  
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sciencedirect.com/science/article/pii/S2211124723011993
Sep 2023
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Protocol for the purification and transcriptomic analysis of mouse astrocytes using GFAT

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.xpro.2023.102599
  
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sciencedirect.com/science/article/pii/S266616672300566X
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Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.cell.2023.08.039
  
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sciencedirect.com/science/article/pii/S009286742300973X
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Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration

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1. scibot 30 Sep 2023
  
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Trem2 Enhances Demyelination in the Csf1r+/− Mouse Model of Leukoencephalopathy

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Human microglia maturation is underpinned by specific gene regulatory networks

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Prophylactic effect of chronic immunosuppression in a mouse model of CSF-1 receptor-related leukoencephalopathy

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Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes

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Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain

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A multi-omics atlas of the human retina at single-cell resolution

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A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

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Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements

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Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF-1 receptor related leukodystrophy

1
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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

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Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function

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Post-surgical latent pain sensitization is driven by descending serotonergic facilitation and masked by µ-opioid receptor constitutive activity (MORCA) in the rostral ventromedial medulla

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Jul 2022
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JNEUROSCI.2038-21.2022.full-html.html

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Mar 2022
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Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus

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Endocannabinoid System Attenuates Oxaliplatin-Induced Peripheral Sensory Neuropathy Through the Activation of CB1 Receptors

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Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice

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Neuronal deficiency of hypoxia-inducible factor 2α increases hypoxic-ischemic brain injury in neonatal mice

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Activity-dependent modulation of synapse-regulating genes in astrocytes

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Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain

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Untitled document

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Reading LINEs within the cocaine addicted brain

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Localization of nectin‐2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage‐gated A‐type K+ channel Kv4.2 in the medial habenula

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Hemopexin Increases the Neurotoxicity of Hemoglobin When Haptoglobin is Absent

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Comprehensive analysis of area‐specific and time‐dependent changes in gene expression in the motor cortex of macaque monkeys during recovery from spinal cord injury

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Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis

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Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra Syndrome

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sciencedirect.com/science/article/pii/S2589004221007094
May 2021
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A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting

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Apr 2021
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Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

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Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction

1
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Nuclei isolation of multiple brain cell types for omics interrogation

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  DOI: 10.1038/s41596-020-00472-3
  
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Neuron-specific analysis of histone modifications with post-mortem brains

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Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation

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  DOI: 10.1016/j.celrep.2020.107843
  
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FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits

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  DOI: 10.1016/j.stem.2020.04.002
  
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A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses

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  DOI: 10.1016/j.celrep.2020.107968
  
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Prefrontal Pathways Provide Top-Down Control of Memory for Sequences of Events

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  DOI: 10.1016/j.celrep.2019.06.053
  
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Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment

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  DOI: 10.1016/j.neuron.2019.09.042
  
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Targeted Cortical Manipulation of Auditory Perception

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  DOI: 10.1016/j.neuron.2019.09.043
  
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Untitled document

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  DOI: 10.1016/j.cmet.2019.03.004
  
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  DOI: 10.1016/j.celrep.2019.04.003
  
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Neuronal activity induces glutathione metabolism gene expression in astrocytes

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onlinelibrary.wiley.com/doi/full/10.1002/glia.23455
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Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool

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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

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Untitled document

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Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase–mTORC1 Translational Pathway

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jneurosci.org/content/38/11/2780
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neurobiologyofaging.org/article/S0197-4580(17)30211-7/abstract
Nov 2017
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Development of a systems‐based in situ multiplex biomarker screening approach for the assessment of immunopathology and neural tissue plasticity in male rats after traumatic brain injury

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Presenilin 1 mutation decreases both calcium and contractile responses in cerebral arteries - ScienceDirect

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Transient acidosis while retrieving a fear-related memory enhances its lability

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1. scibot 08 Nov 2017
  
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Reading LINEs within the cocaine addicted brain

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ncbi.nlm.nih.gov/pmc/articles/PMC5434184/
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Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation

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sciencedirect.com/science/article/pii/S0002929716300623
cercor.oxfordjournals.org cercor.oxfordjournals.org

Ketamine Administration During the Second Postnatal Week Alters Synaptic Properties of Fast-Spiking Interneurons in the Medial Prefrontal Cortex of Adult Mice

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cercor.oxfordjournals.org/content/26/3/1117.long
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Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway

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onlinelibrary.wiley.com/doi/10.1002/jnr.23672/full

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