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A Rac-PI3Kβ feedback loop drives GPVI-dependent platelet activation

1
1. scibot 23 Jul 2026
  
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  AB_2157728
  
  DOI: 10.1016/j.isci.2026.116698
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004226020742
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Step-Wise Assembly of LAT Signaling Clusters Immediately After T Cell Receptor Triggering Contributes to Signal Propagation

1
1. scibot 21 May 2025
  
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  RRID:AB_2157728
  
  DOI: 10.3390/ijms26094076
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12071625/
Mar 2025
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Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia

1
1. scibot 11 Mar 2025
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.ccell.2025.02.008
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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  RRID:AB_2157728
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sciencedirect.com/science/article/pii/S1535610825000601
Mar 2024
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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

2
1. scibot 13 Mar 2024
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.immuni.2024.02.014
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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  RRID:AB_2157728
2. scibot 13 Mar 2024
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.immuni.2024.02.014
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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sciencedirect.com/science/article/pii/S1074761324000906
May 2023
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Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity

1
1. scibot 25 May 2023
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.cmet.2023.05.001
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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sciencedirect.com/science/article/pii/S155041312300178X
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Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment

1
1. scibot 13 May 2023
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.cmet.2023.04.017
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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sciencedirect.com/science/article/pii/S1550413123001717
Jun 2021
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Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch

1
1. scibot 23 Jun 2021
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.celrep.2021.109280
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124721006471
May 2021
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Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses

1
1. scibot 12 May 2021
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.immuni.2021.04.008
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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  RRID:AB_2157728
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sciencedirect.com/science/article/pii/S1074761321001709
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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

1
1. scibot 07 May 2021
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.immuni.2020.09.006
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2157728
  
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sciencedirect.com/science/article/pii/S1074761320304003
Sep 2020
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Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.immuni.2020.07.011
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2157728
  
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  RRIDCUR:Validated RRID:AB_2157728
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1074761320303186
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THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2157728
  
  DOI: 10.1016/j.ccell.2019.12.014
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2157728
  
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  RRIDCUR:Validated RRID:AB_2157728
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1535610819305847
Jan 2020
elifesciences.org elifesciences.org

Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2157728
  
  DOI: 10.7554/eLife.45789
  
  Resource: (Cell Signaling Technology Cat# 3584, RRID:AB_2157728)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2157728
  
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  RRID:AB_2157728 RRIDCUR:Validated
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elifesciences.org/articles/45789
Nov 2018
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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2157728
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3584S, RRID:AB_2157728)
  
  SciCrunch record: RRID:AB_2157728
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2157728
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sciencedirect.com/science/article/pii/S1535610818302186
Nov 2017
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A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

1
1. scibot 08 Nov 2017
  
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  AB_2157728
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3584S, RRID:AB_2157728)
  
  SciCrunch record: RRID:AB_2157728
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2157728 RRIDCUR:Validated
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RRID:AB_2157728

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1097276517304586