75 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
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    1. scibot 15 Nov 2024
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      DOI: 10.1016/j.isci.2024.111283

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    sciencedirect.com/science/article/pii/S2589004224025082
  3. Sep 2024
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004245
  5. Aug 2024
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    Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome
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    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.cmet.2024.07.003

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    sciencedirect.com/science/article/pii/S1550413124002742
  7. www.pnas.org www.pnas.org
    Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer
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    1. scibot 13 Aug 2024
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      DOI: 10.1073/pnas.2319429121

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    pnas.org/doi/10.1073/pnas.2319429121
  8. May 2024
  9. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 25 May 2024
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      DOI: 10.1111/bph.16306

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16306
  10. Apr 2024
  11. www.sciencedirect.com www.sciencedirect.com
    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
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    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.molcel.2024.03.011

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    sciencedirect.com/science/article/pii/S1097276524002211
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
    2
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    sciencedirect.com/science/article/pii/S0092867424002502
  14. Mar 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    1. scibot 29 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001758
  16. Feb 2024
  17. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 27 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  18. www.sciencedirect.com www.sciencedirect.com
    KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1
    1
    1. scibot 08 Feb 2024
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    sciencedirect.com/science/article/pii/S2589004224002451
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer
    1
    1. scibot 01 Feb 2024
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      DOI: 10.1038/s41698-024-00496-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10810864/
  20. Jan 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.isci.2023.108680

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
  22. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
    1
    1. scibot 10 Jan 2024
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  23. www.sciencedirect.com www.sciencedirect.com
    Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair
    1
    1. scibot 09 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113656

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    sciencedirect.com/science/article/pii/S2211124723016674
  24. Aug 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer
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    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.isci.2023.107537

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    sciencedirect.com/science/article/pii/S2589004223016140
  26. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  27. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112984

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    2. scibot 16 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112984

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    52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1038/s41392-023-01554-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10409725/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pre‐culture with transferrin‐Fe3+ before in vitro maturation improves the developmental competence of porcine oocytes matured in vitro
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1002/rmb2.12529

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    ncbi.nlm.nih.gov/pmc/articles/PMC10402462/
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    LRRC15 expression indicates high level of stemness regulated by TWIST1 in mesenchymal stem cells
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    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.isci.2023.106946

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    sciencedirect.com/science/article/pii/S2589004223010234
  32. www.sciencedirect.com www.sciencedirect.com
    Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.ebiom.2023.104670

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    sciencedirect.com/science/article/pii/S2352396423002359
  33. Apr 2023
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
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    1. scibot 05 Apr 2023
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      DOI: 10.1002/jcb.30381

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  35. Feb 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model
    1
    1. scibot 04 Feb 2023
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      DOI: 10.3389/fmolb.2023.1058825

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    ncbi.nlm.nih.gov/pmc/articles/PMC9893022/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
    1
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      DOI: 10.1016/j.isci.2023.105962

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
  38. Jan 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
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    1. scibot 26 Jan 2023
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      DOI: 10.1016/j.devcel.2022.12.012

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    sciencedirect.com/science/article/pii/S1534580722008942
  40. www.sciencedirect.com www.sciencedirect.com
    A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3
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      DOI: 10.1016/j.isci.2023.105935

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    sciencedirect.com/science/article/pii/S2589004223000123
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
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      DOI: 10.1158/0008-5472.CAN-21-2352

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    ncbi.nlm.nih.gov/pmc/articles/PMC9256808/
  42. Nov 2022
  43. link.springer.com link.springer.com
    Hyponatremia-related liver steatofibrosis and impaired spermatogenesis: evidence from a mouse model of the syndrome of inappropriate antidiuresis
    1
    1. scibot 29 Nov 2022
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      DOI: 10.1007/s40618-022-01962-9

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    link.springer.com/article/10.1007/s40618-022-01962-9
  44. aacrjournals.org aacrjournals.org
    A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth
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      DOI: 10.1158/1541-7786.MCR-22-0182

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    aacrjournals.org/mcr/article/20/11/1598/709855/A-Druggable-UHRF1-DNMT1-GLI-Complex-Regulates
  45. www.sciencedirect.com www.sciencedirect.com
    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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      DOI: 10.1016/j.jcmgh.2022.09.006

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    sciencedirect.com/science/article/pii/S2352345X22001989
  46. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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      DOI: 10.1016/j.chembiol.2022.10.005

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    sciencedirect.com/science/article/pii/S2451945622003592
  47. Oct 2022
  48. 52.53.155.43 52.53.155.43
    mcr-22-0182-html.html
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      DOI: 10.1158/1541-7786.mcr-22-0182

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  49. Jul 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization
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      DOI: 10.1016/j.molcel.2022.04.027

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    ncbi.nlm.nih.gov/pmc/articles/PMC9235857/
  51. May 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Topical therapy for regression and melanoma prevention of congenital giant nevi
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      DOI: 10.1016/j.cell.2022.04.025

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    sciencedirect.com/science/article/pii/S009286742200472X
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development
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      DOI: 10.7554/eLife.71142

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    ncbi.nlm.nih.gov/pmc/articles/PMC9064305/
  54. Mar 2022
  55. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14558

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  56. Dec 2021
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    Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair
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  58. Nov 2021
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  60. Oct 2021
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  62. Aug 2021
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  64. Jul 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling
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  67. May 2021
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    Metabolic regulator IAPP (Amylin) is required for BRAF and RAS oncogene-induced senescence
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  69. Apr 2021
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    MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation
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  71. Mar 2021
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    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
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  73. Feb 2021
  74. europepmc.org europepmc.org
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    LncRNA-Malat1 is involved in lipotoxicity-induced β-cell dysfunction and the therapeutic effect of exendin-4 via Ptbp1
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  76. www.nature.com www.nature.com
    PDX1 LOW MAFA LOW β-cells contribute to islet function and insulin release
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  77. Sep 2020
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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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  83. Jan 2020
  84. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition
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    Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration
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    Marine bacterial extracts as a new rich source of drugs against Alzheimer's disease
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    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
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  91. Nov 2018
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    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
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    Exogenous H2S exerts biphasic effects on porcine mammary epithelial cells proliferation through PI3K/Akt‐mTOR signaling pathway
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health
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    Sonic Hedgehog and WNT Signaling Promote Adrenal Gland Regeneration in Male Mice
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    Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut
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  98. Nov 2017
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    Rac1 Dosage Is Crucial for Normal Endochondral Bone Growth
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    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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    CD40 Signaling in Graves Disease Is Mediated Through Canonical and Noncanonical Thyroidal Nuclear Factor κB Activation
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