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Aberrant coupling of glutamate and tyrosine kinase receptors enables neuronal control of brain-tumor growth

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.neuron.2025.08.005
  
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sciencedirect.com/science/article/pii/S0896627325005914
Aug 2025
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Targeting ECM-producing cells with CAR-T therapy alleviates fibrosis in chronic kidney disease

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.stem.2025.07.014
  
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sciencedirect.com/science/article/pii/S1934590925002711
Jul 2025
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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102253
  
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sciencedirect.com/science/article/pii/S266637912500326X
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Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer

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1. scibot 24 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116018
  
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sciencedirect.com/science/article/pii/S2211124725007892
Jun 2025
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Lipocalin-2 regulates astrocyte-oligodendrocyte interaction to drive post-stroke secondary demyelination

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1. scibot 24 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115899
  
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sciencedirect.com/science/article/pii/S2211124725006709
May 2025
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1-s2.0-S2589004225009472-main-html.html

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1. scibot 20 May 2025
  
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  DOI: 10.1016/j.isci.2025.112686
  
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52.53.155.43/7d64354f508456ae57075c28fb963f3a959102eb/1-s2.0-S2589004225009472-main-html.html
Apr 2025
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A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development

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1. scibot 03 Apr 2025
  
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sciencedirect.com/science/article/pii/S2211124725002840
Mar 2025
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Effective targeting of PDGFRA-altered high-grade glioma with avapritinib

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1. scibot 14 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.018
  
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sciencedirect.com/science/article/pii/S1535610825000704
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Outer radial glia promotes white matter regeneration after neonatal brain injury

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1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.101986
  
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cell.com/cell-reports-medicine/abstract/S2666-3791(25)00059-X
Sep 2024
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Profound cellular defects attribute to muscular pathogenesis in the rhesus monkey model of Duchenne muscular dystrophy

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.041
  
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sciencedirect.com/science/article/pii/S009286742400970X
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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.013
  
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sciencedirect.com/science/article/pii/S0092867424009048
Aug 2024
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CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110613
  
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sciencedirect.com/science/article/pii/S2589004224018388
May 2024
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Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice

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1. scibot 09 May 2024
  
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  DOI: 10.1186/s13293-024-00616-0
  
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bsd.biomedcentral.com/articles/10.1186/s13293-024-00616-0
Apr 2024
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Craniofacial Chondrogenesis in Organoids from Human Stem Cell-Derived Neural Crest Cells

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1. scibot 11 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109585
  
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52.53.155.43/c00e282857182b3d04ec5472d5421ef32ea8c27c/1-s2.0-S2589004224008071-main-html.html
Mar 2024
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PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay

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1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.002
  
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2. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.002
  
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sciencedirect.com/science/article/pii/S1535610824000461
Dec 2023
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Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling

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1. scibot 19 Dec 2023
  
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  DOI: 10.1016/j.devcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1534580723006214
Oct 2023
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Trem2 deficiency attenuates microglial phagocytosis and autophagic-lysosomal activation in white matter hypoperfusion

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1. scibot 20 Oct 2023
  
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  DOI: 10.1111/jnc.15987
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15987
Aug 2023
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Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107479
  
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sciencedirect.com/science/article/pii/S2589004223015560
Jul 2023
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Modeling epigenetic lesions that cause gliomas

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.cell.2023.06.022
  
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sciencedirect.com/science/article/abs/pii/S0092867423007298
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Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112801
  
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sciencedirect.com/science/article/pii/S2211124723008124
Jun 2023
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Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.ccell.2023.05.016
  
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sciencedirect.com/science/article/pii/S1535610823001836
Apr 2023
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Modulation of microglial metabolism facilitates regeneration in demyelination

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1. scibot 22 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106588
  
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Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice

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1. scibot 20 Apr 2023
  
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  DOI: 10.1002/jnr.25153
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10107949/
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Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.007
  
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sciencedirect.com/science/article/pii/S1535610823000806
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Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen

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1. scibot 04 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.02.033
  
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sciencedirect.com/science/article/pii/S0092867423002118
Feb 2023
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Sex based comparisons of muscle cellular adaptations after 10-weeks of progressive resistance training in middle-aged adults

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1. scibot 03 Feb 2023
  
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  DOI: 10.1152/japplphysiol.00274.2022
  
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52.53.155.43/9922ffea0ed61fe3d12c1615ada78ff27648d523/japplphysiol.00274.2022-html.html
Dec 2022
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A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates

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1. scibot 11 Dec 2022
  
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Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease

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  DOI: 10.1016/j.stem.2022.11.013
  
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Oct 2022
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CDON contributes to Hedgehog-dependent patterning and growth of the developing limb

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  DOI: 10.1016/j.ydbio.2022.09.011
  
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sciencedirect.com/science/article/pii/S0012160622001828
Sep 2022
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Ral GTPases are critical regulators of spinal cord myelination and homeostasis

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1. scibot 29 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111413
  
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sciencedirect.com/science/article/pii/S2211124722012542
Jun 2022
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Generation of functional chimeric kidney containing exogenous progenitor-derived stroma and nephron via a conditional empty niche

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110933
  
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sciencedirect.com/science/article/pii/S221112472200715X
May 2022
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SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production

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1. scibot 12 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110750
  
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sciencedirect.com/science/article/pii/S2211124722005149
Apr 2022
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Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility

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1. scibot 16 Apr 2022
  
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  DOI: 10.7554/eLife.34829
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5903864/
Mar 2022
www.nature.com www.nature.com

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

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1. scibot 10 Mar 2022
  
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  DOI: 10.1038/s41467-022-28720-y
  
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nature.com/articles/s41467-022-28720-y
Feb 2022
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A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice

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1. scibot 21 Feb 2022
  
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  DOI: 10.1096/fj.202101652R
  
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Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation

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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

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Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1

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Pro-inflammatory and proliferative microglia drive progression of glioblastoma

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Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

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Pen-2 negatively regulates the differentiation of oligodendrocyte precursor cells into astrocytes in the central nervous system

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Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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Highly efficient manipulation of nervous system gene expression with NEPTUNE

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Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity

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Origins and Proliferative States of Human Oligodendrocyte Precursor Cells

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Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer

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Endothelial Wnts control mammary epithelial patterning via fibroblast signaling

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Optic nerve regeneration screen identifies multiple genes restricting adult neural repair

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Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants

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QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis

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Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing

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Deletion of PDK1 in oligodendrocyte lineage cells causes white matter abnormality and myelination defect in the central nervous system

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GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation

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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells

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The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis

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Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma

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Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition

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CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

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Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

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Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function

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Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase

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Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination

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Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development

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Untitled document

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Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids

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