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TLR ligand sensing by lymph node FRCs directs intranodal lymphocyte accumulation to promote immune responses

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113734
  
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sciencedirect.com/science/article/pii/S2589004225019959
Oct 2025
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TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis

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1. scibot 23 Oct 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-4224
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618269/
Sep 2025
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Integrated spatial transcriptomic profiling to dissect the cellular characteristics of tumor-associated tertiary lymphoid structures

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116250
  
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sciencedirect.com/science/article/pii/S2211124725010216
Jul 2025
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Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer

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1. scibot 24 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116018
  
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TNF-α-NF-κB activation through pathological α-Synuclein disrupts the BBB and exacerbates axonopathy

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116001
  
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Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2024.05.025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11246234/
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Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids

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May 2025
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Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

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1. scibot 16 May 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2220
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
Apr 2025
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Fate and state transitions during human blood vessel organoid development

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1. scibot 19 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.037
  
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KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115576
  
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sciencedirect.com/science/article/pii/S221112472500347X
Jan 2025
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Tubulointerstitial nephritis antigen-like 1 promotes the progression of liver fibrosis after HCV eradication with direct-acting antivirals

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1. scibot 16 Jan 2025
  
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  DOI: 10.7150/ijbs.103305
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11705640/
Dec 2024
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Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.immuni.2018.04.006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5971117/
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1-s2.0-S2589004224027433-main-html.html

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1. scibot 06 Dec 2024
  
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  AB_2162497
  
  DOI: 10.1016/j.isci.2024.111516
  
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52.53.155.43/4cd936c6d252d720783f395bd288e7a8753b9204/1-s2.0-S2589004224027433-main-html.html
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Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.stem.2024.10.015
  
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sciencedirect.com/science/article/pii/S1934590924003771
Nov 2024
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Chemoresistance-Motility Signature of Molecular Evolution to Chemotherapy in Non-Muscle-Invasive Bladder Cancer and Its Clinical Implications

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1. scibot 29 Nov 2024
  
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  DOI: 10.1016/j.canlet.2024.217339
  
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sciencedirect.com/science/article/pii/S0304383524007341
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HucMSCs can alleviate abnormal vasculogenesis induced by high glucose through the MAPK signaling pathway

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111354
  
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sciencedirect.com/science/article/pii/S2589004224025793
Oct 2024
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Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow

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1. scibot 08 Oct 2024
  
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  DOI: 10.1038/s41467-024-52969-0
  
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link.springer.com/article/10.1038/s41467-024-52969-0
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BPS Publications

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1. scibot 08 Oct 2024
  
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  DOI: 10.1111/bph.17347
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17347
Sep 2024
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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.013
  
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sciencedirect.com/science/article/pii/S0092867424009048
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Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114697
  
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sciencedirect.com/science/article/pii/S2211124724010489
Jun 2024
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Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies

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1. scibot 29 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110068
  
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cell.com/iscience/abstract/S2589-0042(24)01293-8
May 2024
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Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.stem.2024.04.019
  
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A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1

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1. scibot 08 May 2024
  
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  DOI: 10.1016/j.cmet.2024.04.015
  
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sciencedirect.com/science/article/pii/S1550413124001359
Apr 2024
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Targeting PDGF signaling of cancer-associated fibroblasts blocks feedback activation of HIF-1α and tumor progression of clear cell ovarian cancer

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1. scibot 26 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101532
  
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sciencedirect.com/science/article/pii/S2666379124002015
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Oligodendrocyte-derived laminin-γ1 regulates the blood-brain barrier and CNS myelination in mice

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114123
  
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sciencedirect.com/science/article/pii/S2211124724004510
Feb 2024
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Methionine secreted by tumor-associated pericytes supports cancer stem cells in clear cell renal carcinoma

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1. scibot 23 Feb 2024
  
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cell.com/cell-metabolism/abstract/S1550-4131(24)00018-4
Dec 2023
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Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling

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1. scibot 19 Dec 2023
  
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  DOI: 10.1016/j.devcel.2023.11.023
  
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Nov 2023
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Astragaloside IV promotes cerebral angiogenesis and neurological recovery after focal ischemic stroke in mice via activating PI3K/Akt/mTOR signaling pathway

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.heliyon.2023.e22800
  
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sciencedirect.com/science/article/pii/S2405844023100089
Aug 2023
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An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver

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1. scibot 24 Aug 2023
  
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  DOI: 10.1038/s41467-023-40688-x
  
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nature.com/articles/s41467-023-40688-x
Jun 2023
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Acetate controls endothelial-to-mesenchymal transition

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.cmet.2023.05.010
  
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Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis

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1. scibot 09 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106988
  
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sciencedirect.com/science/article/pii/S2589004223010659
Mar 2023
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A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.crmeth.2023.100431
  
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sciencedirect.com/science/article/pii/S2667237523000462
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Transcriptome analysis reveals tumor microenvironment changes in glioblastoma

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1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.02.019
  
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sciencedirect.com/science/article/pii/S1535610823000478
Feb 2023
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DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1

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1. scibot 01 Feb 2023
  
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  DOI: 10.1158/2767-9764.crc-22-0013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9881645/
Nov 2022
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Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2

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  RRID:AB_2162497
  
  DOI: 10.1016/j.celrep.2022.111709
  
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DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1

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  DOI: 10.1158/2767-9764.CRC-22-0013
  
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Sep 2022
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Vaccination-based immunotherapy to target profibrotic cells in liver and lung

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Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions

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  DOI: 10.1016/j.neuron.2022.07.010
  
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PDGFRβ+ cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

1
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  RRID:AB_2920526
  
  DOI: 10.1016/j.celrep.2022.111114
  
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May 2022
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SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production

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Blood-brain barrier permeability is regulated by lipid transport-dependent suppression of caveolae-mediated transcytosis

1
1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.neuron.2017.03.043
  
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Mar 2022
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Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier

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  DOI: 10.1016/j.neuron.2022.02.017
  
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Sox10-cre BAC transgenes reveal temporal restriction of mesenchymal cranial neural crest and identify glandular Sox10 expression.

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Dec 2021
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Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation

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Jul 2021
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Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats

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  DOI: 10.1111/jnc.15383
  
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Parenchymal pericytes are not the major contributor of extracellular matrix in the fibrotic scar after stroke in male mice

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1. scibot 30 Jul 2021
  
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  DOI: 10.1002/jnr.24557
  
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A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis

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Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

1
1. scibot 27 Jul 2021
  
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  AB_2162497
  
  DOI: 10.1016/j.neuron.2017.03.043
  
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May 2021
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Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity

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  DOI: 10.1016/j.stem.2020.12.008
  
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Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche That Maintains and Replenishes Splenic Red Pulp Macrophages

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.06.008
  
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Apr 2021
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Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

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1. scibot 23 Apr 2021
  
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  RRID:AB_AB_2162497
  
  DOI: 10.1016/j.cell.2020.02.003
  
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The bone microenvironment invigorates metastatic seeds for further dissemination

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  DOI: 10.1016/j.cell.2021.03.011
  
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The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

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  RRID:AB_2162497
  
  DOI: 10.1016/j.devcel.2021.03.008
  
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Donor cell memory confers a metastable state of directly converted cells

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1. scibot 13 Apr 2021
  
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  RRID:AB_2162497
  
  DOI: 10.1016/j.stem.2021.02.023
  
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Oct 2020
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Developmental Renal Glomerular Defects at the Origin of Glomerulocystic Disease

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1. scibot 31 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108304
  
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Sep 2020
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An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction

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  AB_2162497
  
  DOI: 10.1371/journal.pone.0232564
  
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In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus

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  RRID:AB_2162497
  
  DOI: 10.1016/j.celrep.2020.107631
  
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Jan 2020
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PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration

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  RRID:AB_2162497
  
  DOI: 10.1016/j.celrep.2019.06.065
  
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Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells

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  DOI: 10.1016/j.celrep.2019.05.077
  
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Impairment of pericyte-endothelium crosstalk leads to blood-brain barrier dysfunction following traumatic brain injury

1
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  RRID:AB_2162497
  
  DOI: 10.1016/j.expneurol.2019.03.014
  
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Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis

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  DOI: 10.1016/j.stem.2019.09.009
  
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Nov 2018
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Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury

1
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ncbi.nlm.nih.gov/pmc/articles/PMC5871719/
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Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development

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Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury

1
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Nov 2017
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Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung

1
1. scibot 08 Nov 2017
  
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Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids

1
1. scibot 08 Nov 2017
  
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  Curator: @kaitlinsung
  
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elifesciences.org/articles/26575

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