41 Matching Annotations
  1. Aug 2024
  2. josr-online.biomedcentral.com josr-online.biomedcentral.com
    Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway
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    1. scibot 02 Aug 2024
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      DOI: 10.1186/s13018-021-02715-9

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    josr-online.biomedcentral.com/articles/10.1186/s13018-021-02715-9
  3. Jul 2024
  4. www.sciencedirect.com www.sciencedirect.com
    PIK3CA mutations enhance the adipogenesis of ADSCs in facial infiltrating lipomatosis through TRPV1
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.isci.2024.110467

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    sciencedirect.com/science/article/pii/S2589004224016924
  5. Jun 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta
    1
    1. scibot 03 Jun 2024
      RRID:AB_2165248

      DOI: 10.1016/j.isci.2024.109921

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    ncbi.nlm.nih.gov/pmc/articles/PMC11133927/
  7. May 2024
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
    1
    1. scibot 14 May 2024
      RRID:AB_2165248

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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
  9. Apr 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect
    1
    1. scibot 24 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004601
  11. www.sciencedirect.com www.sciencedirect.com
    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114119

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    sciencedirect.com/science/article/pii/S2211124724004479
  12. Mar 2024
  13. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
    1
    1. scibot 21 Mar 2024
      RRID:AB_2165248

      DOI: 10.1101/2024.03.03.583221

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    biorxiv.org/content/10.1101/2024.03.03.583221v1
  14. Jan 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1158/1078-0432.CCR-23-1317

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    ncbi.nlm.nih.gov/pmc/articles/PMC10767308/
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Epinephrine inhibits PI3Kα via the Hippo kinases
    1
    1. scibot 20 Dec 2023
      RRID:AB_2165248

      DOI: 10.1016/j.celrep.2023.113535

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    sciencedirect.com/science/article/pii/S2211124723015474
  19. dx.doi.org dx.doi.org
    Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus
    1
    1. scibot 15 Dec 2023
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      DOI: 10.1210/clinem/dgad699

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    dx.doi.org/10.1210/clinem/dgad699
  20. 52.53.155.43 52.53.155.43
    ccr-23-1317-html.html
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    1. scibot 01 Dec 2023
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  21. Aug 2023
  22. www.sciencedirect.com www.sciencedirect.com
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    1
    1. scibot 11 Aug 2023
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      DOI: 10.1016/j.molcel.2023.07.015

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    sciencedirect.com/science/article/pii/S1097276523005580
  23. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 01 Aug 2023
      RRID:AB_2165248

      DOI: 10.1111/bph.16202

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    52.53.155.43/d8c850c315bd1ef9a1794152cac296a4123affe5/British J Pharmacology - 2023 - Wang - Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3-html.html
  24. Jul 2023
  25. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    2
    1. scibot 18 Jul 2023
      RRID:AB_2165248

      DOI: 10.1101/2023.05.18.541123

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    52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
  26. Jun 2023
  27. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  28. May 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
    1
    1. scibot 20 May 2023
      RRID: AB_2165248

      DOI: 10.1016/j.bcp.2023.115612

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    sciencedirect.com/science/article/pii/S0006295223002034
  30. Apr 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
    1
    1. scibot 04 Apr 2023
      RRID:AB_2165248

      DOI: 10.1016/j.celrep.2023.112319

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    sciencedirect.com/science/article/pii/S2211124723003303
  32. Mar 2023
  33. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
    1
    1. scibot 02 Mar 2023
      RRID:AB_2165248

      DOI: 10.1016/j.celrep.2023.112188

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    sciencedirect.com/science/article/pii/S2211124723001997
  34. Jan 2023
  35. journals.lww.com journals.lww.com
    PTEN inhibitor bisperoxovanadium protects against... : Neural Regeneration Research
    1
    1. scibot 19 Jan 2023
      RRID:AB_2165248

      DOI: 10.4103/1673-5374.358606

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    journals.lww.com/nrronline/Fulltext/2023/07000/PTEN_inhibitor_bisperoxovanadium_protects_against.36.aspx
  36. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 14 Jan 2023
      RRID:AB_2165248

      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  37. Dec 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis
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    1. scibot 17 Dec 2022
      RRID:AB_2165248

      DOI: 10.1016/j.cmet.2022.11.012

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    sciencedirect.com/science/article/pii/S1550413122005034
  39. Nov 2022
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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    1. scibot 19 Nov 2022
      RRID:AB_2165248

      DOI: 10.1158/2767-9764.crc-22-0024

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
  41. Jul 2022
  42. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
    1
    1. scibot 29 Jul 2022
      RRID:AB_2165248

      DOI: 10.1158/2767-9764.CRC-22-0024

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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  43. Jun 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic screens identify a context-specific PI3K/p27Kip1 node driving extrahepatic biliary cancer
    1
    1. scibot 07 Jun 2022
      RRID:AB_2165248

      DOI: 10.1158/2159-8290.CD-21-0209

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    ncbi.nlm.nih.gov/pmc/articles/PMC7612573/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
    1
    1. scibot 01 Jun 2022
      RRID:AB_2165248

      DOI: 10.3389/fphar.2022.848957

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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
  46. Feb 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
    2
    1. scibot 11 Feb 2022
      RRID:AB_2165248

      DOI: 10.1016/j.ebiom.2022.103847

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.ebiom.2022.103847

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    sciencedirect.com/science/article/pii/S2352396422000317
  48. Aug 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.ebiom.2018.09.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC6197754/
  50. May 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression
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      DOI: 10.1016/j.molcel.2020.09.027

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    sciencedirect.com/science/article/pii/S1097276520306572
  52. www.cell.com www.cell.com
    LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome
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      DOI: 10.1016/j.cell.2021.04.001

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    cell.com/cell/fulltext/S0092-8674(21)00436-0
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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      DOI: 10.1016/j.ccell.2021.02.016

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    sciencedirect.com/science/article/pii/S1535610821001185
  55. Oct 2020
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma
    1
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      PI3K

      DOI: 10.1002/cac2.12103

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    onlinelibrary.wiley.com/doi/full/10.1002/cac2.12103
  57. Sep 2020
  58. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas
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      DOI: 10.1016/j.celrep.2020.108196

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    pubmed.ncbi.nlm.nih.gov/32997991/
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effect of angiotensin II and angiotensin‐(1–7) on proliferation of stem cells from human dental apical papilla
    1
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      DOI: 10.1002/jcp.29862

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29862
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
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      RRID:AB_2165248

      DOI: 10.1016/j.molcel.2019.08.021

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    sciencedirect.com/science/article/pii/S1097276519306604
  62. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_2165248

      DOI: 10.1016/j.molcel.2018.12.001

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    sciencedirect.com/science/article/pii/S1097276518310311
  63. Nov 2018
  64. www.sciencedirect.com www.sciencedirect.com
    PI3Kγ promotes vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis via a SOX9-dependent mechanism
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    sciencedirect.com/science/article/pii/S2352396418303712
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calorie Restriction-Induced Increase in Skeletal Muscle Insulin Sensitivity Is Not Prevented by Overexpression of the p55α Subunit of Phosphoinositide 3-Kinase
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    1. scibot 05 Nov 2018
      RRID:AB_2165248

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      RRID:AB_2165248
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    ncbi.nlm.nih.gov/pmc/articles/PMC6030672/
  66. Nov 2017
  67. elifesciences.org elifesciences.org
    SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
    1
    1. scibot 08 Nov 2017
      AB_2165248

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 4249S, RRID:AB_2165248)

      SciCrunch record: RRID:AB_2165248

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      RRID:AB_2165248 RRIDCUR:Validated
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    elifesciences.org/content/6/e25158