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A bifunctional ARHGEF17-AS1 locus encodes MSEP, a protein that supports mitotic spindle organization

1
1. scibot 01 Oct 2026
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.celrep.2026.118026
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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sciencedirect.com/science/article/pii/S2211124726011046
Jun 2026
aacrjournals.org aacrjournals.org

Targeting PLK1 Reduces MMP10 to Enhance Radiosensitivity in HPV- Head and Neck Cancer

1
1. scibot 24 Jun 2026
  
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  RRID:AB_2167409
  
  DOI: 10.1158/1078-0432.CCR-25-2179
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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aacrjournals.org/clincancerres/article/32/2/405/771743/Targeting-PLK1-Reduces-MMP10-to-Enhance
Apr 2026
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An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation

1
1. scibot 09 Apr 2026
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.molcel.2026.03.004
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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sciencedirect.com/science/article/pii/S1097276526001607
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NN-01-195, a novel conjugate of HSP90 and AURKA inhibitors, effectively targets solid tumors

1
1. scibot 18 Mar 2026
  
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  RRID:AB_2167409
  
  DOI: 10.1158/1535-7163.MCT-25-0857
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12977774/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Integrative proteogenomics and forward genetics reveals a novel mitotic vulnerability in triple-negative breast cancer

1
1. scibot 26 Nov 2025
  
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  RRID:AB_2167409
  
  DOI: 10.1158/2159-8290.CD-23-1173
  
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  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12641601/
May 2025
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Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

1
1. scibot 16 May 2025
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.cell.2025.04.012
  
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sciencedirect.com/science/article/pii/S0092867425004143
Apr 2025
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PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

1
1. scibot 08 Apr 2025
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.celrep.2025.115541
  
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sciencedirect.com/science/article/pii/S2211124725003122
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis

1
1. scibot 04 Apr 2025
  
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  RRID:AB_2167409
  
  DOI: 10.1158/2159-8290.CD-24-0442
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11962402/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MYC and HSF1 Cooperate to Drive Sensitivity to Polo-like Kinase 1 Inhibitor Volasertib in High-grade Serous Ovarian Cancer

1
1. scibot 08 Feb 2025
  
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  RRID:AB_2167409
  
  DOI: 10.1158/2767-9764.CRC-24-0400
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11799878/
Dec 2024
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Mapping functional elements of the DNA damage response through base editor screens

1
1. scibot 12 Dec 2024
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.celrep.2024.115047
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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sciencedirect.com/science/article/pii/S2211124724013986
Nov 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies

1
1. scibot 15 Nov 2024
  
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  RRID:AB_2167409
  
  DOI: 10.1002/advs.202404109
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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onlinelibrary.wiley.com/doi/full/10.1002/advs.202404109
Sep 2024
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The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance

1
1. scibot 25 Sep 2024
  
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  RRID:AB_613880
  
  DOI: 10.1016/j.celrep.2020.108102
  
  Resource: (IMGENEX Cat# IMG-5297A, RRID:AB_613880)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_613880
  
  Curator comments: PLK1 (208G4) Rabbit mAb antibody Cell Signaling Technology Cat# 4513
  
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  RRIDCUR:Incorrect RRID:AB_613880 RRID:AB_2167409
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sciencedirect.com/science/article/pii/S2211124720310913
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

1
1. scibot 17 Jul 2024
  
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  AB_2167409
  
  DOI: 10.1016/j.xcrm.2024.101645
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells

1
1. scibot 03 Jul 2024
  
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  RRID:AB_2167409
  
  DOI: 10.3389/fonc.2024.1394653
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11199525/
May 2024
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Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators

1
1. scibot 24 May 2024
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.ccell.2024.05.002
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1535610824001636
www.biorxiv.org www.biorxiv.org

Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells

1
1. scibot 23 May 2024
  
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  RRID:AB_2167409
  
  DOI: 10.1101/2024.05.13.593567
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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biorxiv.org/content/10.1101/2024.05.13.593567v1
Jul 2023
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Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice

1
1. scibot 15 Jul 2023
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.celrep.2023.112812
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723008239
www.nature.com www.nature.com

Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma

1
1. scibot 08 Jul 2023
  
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  RRID:AB_2167409
  
  DOI: 10.1038/s41420-023-01526-7
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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nature.com/articles/s41420-023-01526-7
Apr 2023
www.mdpi.com www.mdpi.com

TEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC

1
1. scibot 20 Apr 2023
  
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  RRID:AB_2167409
  
  DOI: 10.3390/ph16040553
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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mdpi.com/1424-8247/16/4/553
Feb 2023
aacrjournals.org aacrjournals.org

Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

1
1. scibot 10 Feb 2023
  
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  RRID:AB_2167409
  
  DOI: 10.1158/0008-5472.CAN-22-1533
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
Nov 2022
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pericentriolar matrix (PCM) integrity relies on cenexin and polo-like kinase (PLK)1

1
1. scibot 04 Nov 2022
  
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  RRID:AB_2167409
  
  DOI: 10.1091/mbc.E22-01-0015
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9582643/
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Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death

1
1. scibot 03 Nov 2022
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.chembiol.2022.10.005
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
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sciencedirect.com/science/article/pii/S2451945622003592
May 2022
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AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma

1
1. scibot 26 May 2022
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.isci.2022.104398
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004222006691
Dec 2021
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Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence

1
1. scibot 18 Dec 2021
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.isci.2021.103558
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004221015285
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation

1
1. scibot 11 Dec 2021
  
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  RRID:AB_2167409
  
  DOI: 10.7554/eLife.70715
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8641947/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation

1
1. scibot 14 Jul 2021
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.celrep.2021.109343
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124721007191
May 2021
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Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability

1
1. scibot 05 May 2021
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.devcel.2020.11.012
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1534580720308881
Sep 2020
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PLK1- and PLK4-Mediated Asymmetric Mitotic Centrosome Size and Positioning in the Early Zebrafish Embryo

1
1. scibot 11 Sep 2020
  
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  RRID:AB_2167409
  
  DOI: 10.1016/j.cub.2020.08.074
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2167409
  
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  RRIDCUR:Validated RRID:AB_2167409
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sciencedirect.com/science/article/pii/S0960982220312641
Jan 2020
royalsocietypublishing.org royalsocietypublishing.org

Oncogenic MYC amplifies mitotic perturbations

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2167409
  
  DOI: 10.1098/rsob.190136
  
  Resource: (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2167409
  
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  RRID:AB_2167409 RRIDCUR:Validated
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royalsocietypublishing.org/doi/full/10.1098/rsob.190136
Nov 2018
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Systematic Functional Annotation of Somatic Mutations in Cancer

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2167409
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  SciCrunch record: RRID:AB_2167409
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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sciencedirect.com/science/article/pii/S1535610818300217
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

1
1. scibot 08 Nov 2017
  
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  AB_2167409
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4513, RRID:AB_2167409)
  
  SciCrunch record: RRID:AB_2167409
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2167409 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590917301376