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<fc>AMPK</fc>/Autophagy‐Dependent Pro‐Adipogenic Effect Coupled With Enhanced Lipid Mobilization and Thermogenesis Underlies the Dual Action of Canagliflozin Against Obesity

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1. scibot 24 Sep 2026
  
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  DOI: 10.1096/fj.202602506R
  
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2. scibot 24 Sep 2026
  
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  DOI: 10.1096/fj.202602506R
  
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faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202602506R
May 2026
dx.doi.org dx.doi.org

Bmal1 regulates thermogenic function by modulation of lipolytic and OXPHOS gene expression in male mice brown adipocytes

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1. scibot 29 May 2026
  
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  DOI: 10.1210/endocr/bqag023
  
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dx.doi.org/10.1210/endocr/bqag023
Apr 2026
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A skin-hypothalamus axis couples heat stress and metabolic dysfunction

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.03.045
  
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sciencedirect.com/science/article/pii/S0092867426003466
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Oxytocin signaling in adipocytes is required for normal milk fat production

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.cmet.2026.03.013
  
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sciencedirect.com/science/article/pii/S1550413126001075
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Panx1 deficiency exacerbates GAN diet-induced obesity by destabilizing β-catenin via GSK3β

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1. scibot 21 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115098
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12999355/
Feb 2026
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MEDAG functions as an A-kinase-anchoring protein in adipocytes

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.02.001
  
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sciencedirect.com/science/article/pii/S1097276526000961
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Novel assessment of post-prandial metabolism reveals sex-specific metabolic flexibility and lipid remodeling following volumetric muscle loss

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1. scibot 25 Feb 2026
  
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  DOI: 10.1152/ajpregu.00259.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12921476/
Jan 2026
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DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function

1
1. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.cmet.2025.12.009
  
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sciencedirect.com/science/article/pii/S1550413125005406
Dec 2025
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Purmorphamine exerts anti-obesity effects by enhancing secretin-activated brown fat thermogenesis

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116628
  
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sciencedirect.com:5037/science/article/pii/S2211124725014007
Nov 2025
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Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116577
  
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sciencedirect.com/science/article/pii/S221112472501349X
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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116526
  
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sciencedirect.com/science/article/pii/S2211124725012975
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The lipid droplet protein DHRS3 is a regulator of melanoma cell state

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1. scibot 01 Nov 2025
  
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  DOI: 10.1111/pcmr.13208
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12244328/
Oct 2025
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PNPLA3-I148M is a neomorph that interferes with two primary hepatic triglyceride clearance pathways

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116371
  
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sciencedirect.com/science/article/pii/S2211124725011428
Aug 2025
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Dissection of surface area-dependent lipolysis at a single organelle level

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116100
  
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sciencedirect.com/science/article/pii/S221112472500871X
Jul 2025
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AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice

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1. scibot 02 Jul 2025
  
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  DOI: 10.1152/ajpendo.00012.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11390115/
Mar 2025
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Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.03.002
  
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sciencedirect.com/science/article/pii/S1074761325000962
Feb 2025
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An organism-level quantitative flux model of energy metabolism in mice

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1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.008
  
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sciencedirect.com/science/article/pii/S1550413125000087
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies

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1. scibot 22 Dec 2024
  
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  DOI: 10.3390/nu16223919
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11597385/
Sep 2024
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Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.apsb.2024.09.010
  
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sciencedirect.com/science/article/pii/S2211383524003733
Aug 2024
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Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cmet.2024.07.016
  
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sciencedirect.com/science/article/pii/S1550413124002870
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Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114573
  
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cell.com/cell-reports/abstract/S2211-1247(24)00902-1
Jul 2024
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Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis

2
1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110346
  
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2. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110346
  
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cell.com/iscience/fulltext/S2589-0042(24)01571-2
May 2024
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ATGL mediated adipocyte lipolysis exacerbates acute pancreatitis severity in mouse models and patients

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1. scibot 07 May 2024
  
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  DOI: 10.1016/j.ajpath.2024.03.014
  
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sciencedirect.com/science/article/pii/S0002944024001652
Dec 2023
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Subcutaneous white adipose tissue independently regulates burn-induced hypermetabolism via immune-adipose crosstalk

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113584
  
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sciencedirect.com/science/article/pii/S2211124723015966
Sep 2023
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Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.jlr.2023.100450
  
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sciencedirect.com/science/article/pii/S0022227523001232
Aug 2023
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Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism

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1. scibot 19 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107450
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
Jul 2023
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Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.07.001
  
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sciencedirect.com/science/article/pii/S1534580723003313
Apr 2023
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Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

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1. scibot 21 Apr 2023
  
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  DOI: 10.1016/j.cmet.2023.03.021
  
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sciencedirect.com/science/article/pii/S1550413123001262
Feb 2023
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Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.devcel.2023.01.007
  
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sciencedirect.com/science/article/pii/S1534580723000382
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PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

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1. scibot 10 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112091
  
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sciencedirect.com/science/article/pii/S221112472300102X
Jun 2022
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A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.cmet.2022.05.009
  
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sciencedirect.com/science/article/pii/S1550413122001917
Feb 2022
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Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis

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1. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.bbalip.2022.159121
  
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2. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.bbalip.2022.159121
  
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sciencedirect.com/science/article/pii/S1388198122000117
Sep 2021
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High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis inactivated Δ6-fatty acid desaturase deficient mouse

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1. scibot 23 Sep 2021
  
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  DOI: 10.1016/j.molmet.2021.101335
  
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sciencedirect.com/science/article/pii/S2212877821001824
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Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism

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1. scibot 22 Sep 2021
  
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Validating an artificial organelle: Studies of lipid droplet-specific proteins on adiposome platform

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Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1

1
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  Rabbit polyclonal anti-ATGL
  
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C1q/TNF-related protein 2 (CTRP2) deletion promotes adipose tissue lipolysis and hepatic triglyceride secretion

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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

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An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

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Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner

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Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism

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Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5

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  DOI: 10.1038/s41467-019-14176-0
  
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Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD

1
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  ATGL
  
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Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression

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Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis

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Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication

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ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes

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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

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Untitled document

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GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

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Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue

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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

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Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue

2
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