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Purmorphamine exerts anti-obesity effects by enhancing secretin-activated brown fat thermogenesis

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116628
  
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sciencedirect.com:5037/science/article/pii/S2211124725014007
Nov 2025
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Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG

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1. scibot 22 Nov 2025
  
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sciencedirect.com/science/article/pii/S221112472501349X
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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116526
  
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sciencedirect.com/science/article/pii/S2211124725012975
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The lipid droplet protein DHRS3 is a regulator of melanoma cell state

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1. scibot 01 Nov 2025
  
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  DOI: 10.1111/pcmr.13208
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12244328/
Oct 2025
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PNPLA3-I148M is a neomorph that interferes with two primary hepatic triglyceride clearance pathways

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1. scibot 08 Oct 2025
  
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sciencedirect.com/science/article/pii/S2211124725011428
Aug 2025
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Dissection of surface area-dependent lipolysis at a single organelle level

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1. scibot 08 Aug 2025
  
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Jul 2025
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AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice

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1. scibot 02 Jul 2025
  
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  DOI: 10.1152/ajpendo.00012.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11390115/
Mar 2025
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Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.03.002
  
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sciencedirect.com/science/article/pii/S1074761325000962
Feb 2025
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An organism-level quantitative flux model of energy metabolism in mice

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1. scibot 21 Feb 2025
  
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sciencedirect.com/science/article/pii/S1550413125000087
Dec 2024
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The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies

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1. scibot 22 Dec 2024
  
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  DOI: 10.3390/nu16223919
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11597385/
Sep 2024
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Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism

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1. scibot 17 Sep 2024
  
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  AB_2167955
  
  DOI: 10.1016/j.apsb.2024.09.010
  
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sciencedirect.com/science/article/pii/S2211383524003733
Aug 2024
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Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cmet.2024.07.016
  
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sciencedirect.com/science/article/pii/S1550413124002870
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Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114573
  
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cell.com/cell-reports/abstract/S2211-1247(24)00902-1
Jul 2024
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Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis

2
1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110346
  
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2. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110346
  
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cell.com/iscience/fulltext/S2589-0042(24)01571-2
May 2024
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ATGL mediated adipocyte lipolysis exacerbates acute pancreatitis severity in mouse models and patients

1
1. scibot 07 May 2024
  
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  2138S
  
  DOI: 10.1016/j.ajpath.2024.03.014
  
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sciencedirect.com/science/article/pii/S0002944024001652
Dec 2023
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Subcutaneous white adipose tissue independently regulates burn-induced hypermetabolism via immune-adipose crosstalk

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113584
  
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sciencedirect.com/science/article/pii/S2211124723015966
Sep 2023
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Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.jlr.2023.100450
  
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sciencedirect.com/science/article/pii/S0022227523001232
Aug 2023
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Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism

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1. scibot 19 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107450
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
Jul 2023
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Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.07.001
  
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sciencedirect.com/science/article/pii/S1534580723003313
Apr 2023
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Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

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1. scibot 21 Apr 2023
  
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sciencedirect.com/science/article/pii/S1550413123001262
Feb 2023
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Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.devcel.2023.01.007
  
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sciencedirect.com/science/article/pii/S1534580723000382
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PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

1
1. scibot 10 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112091
  
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sciencedirect.com/science/article/pii/S221112472300102X
Jun 2022
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A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.cmet.2022.05.009
  
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sciencedirect.com/science/article/pii/S1550413122001917
Feb 2022
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Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis

2
1. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.bbalip.2022.159121
  
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  DOI: 10.1016/j.bbalip.2022.159121
  
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sciencedirect.com/science/article/pii/S1388198122000117
Sep 2021
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High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis inactivated Δ6-fatty acid desaturase deficient mouse

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1. scibot 23 Sep 2021
  
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  DOI: 10.1016/j.molmet.2021.101335
  
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sciencedirect.com/science/article/pii/S2212877821001824
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Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism

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1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109742
  
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sciencedirect.com/science/article/pii/S2211124721011955
Aug 2021
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Validating an artificial organelle: Studies of lipid droplet-specific proteins on adiposome platform

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.isci.2021.102834
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8326204/
academic.oup.com academic.oup.com

Untitled document

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1. scibot 03 Aug 2021
  
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  DOI: 10.1210/en.2016-1809
  
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academic.oup.com/endo/article/158/5/1231/3074048
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Untitled document

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  DOI: 10.1210/en.2016-1809
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5460841/
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Untitled document

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  DOI: 10.1210/en.2018-00797
  
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academic.oup.com/endo/article/160/2/293/5239798
Jul 2021
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Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1

1
1. scibot 31 Jul 2021
  
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  Rabbit polyclonal anti-ATGL
  
  DOI: 10.1016/j.molcel.2019.12.003
  
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sciencedirect.com/science/article/pii/S1097276519308949
www.jbc.org www.jbc.org

C1q/TNF-related protein 2 (CTRP2) deletion promotes adipose tissue lipolysis and hepatic triglyceride secretion

1
1. scibot 31 Jul 2021
  
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  anti-ATGL
  
  DOI: 10.1074/jbc.RA119.009230
  
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jbc.org/content/294/43/15638.full
May 2021
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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

1
1. scibot 28 May 2021
  
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  RRID:AB_2167955
  
  DOI: 10.1016/j.cell.2021.04.037
  
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sciencedirect.com/science/article/pii/S0092867421005729
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

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1. scibot 06 Jan 2021
  
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  RRID:AB_2167955
  
  DOI: 10.7554/eLife.63665
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7758072/
Oct 2020
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Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner

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1. scibot 02 Oct 2020
  
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  RRID:AB_2167955
  
  DOI: 10.1016/j.redox.2020.101742
  
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sciencedirect.com/science/article/pii/S2213231720309472
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Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism

1
1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.089
  
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Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5

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1. scibot 13 Sep 2020
  
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  DOI: 10.1038/s41467-019-14176-0
  
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nature.com/articles/s41467-019-14176-0
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD

1
1. scibot 04 Sep 2020
  
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  DOI: 10.1096/fj.202000678R
  
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Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression

1
1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.01.014
  
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Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis

1
1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.molcel.2019.12.002
  
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Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.05.030
  
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ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.07.030
  
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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2167955
  
  DOI: 10.1016/j.cmet.2019.10.006
  
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Nov 2018
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Untitled document

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GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

1
1. scibot 05 Nov 2018
  
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Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue

2
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2. scibot 05 Nov 2018
  
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Nov 2017
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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

1
1. scibot 08 Nov 2017
  
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Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue

2
1. scibot 08 Nov 2017
  
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2. scibot 08 Nov 2017
  
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  AB_2167955
  
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academic.oup.com/endo/article/158/5/1231/3074048/Hypoxia-Inducible-Lipid-Droplet-Associated-Is-Not