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Cancer-linked ANKRD26-RET uses an unusual combination of pathomechanisms leading to strongly increased cell proliferation

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1. scibot 13 May 2026
  
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  RRID:AB_2179887
  
  DOI: 10.1016/j.biopha.2026.119479
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2179887
  
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  RRID:AB_2179887
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sciencedirect.com/science/article/pii/S0753332226005159
May 2024
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Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC

1
1. scibot 21 May 2024
  
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  RRID:AB_2179887
  
  DOI: 10.1016/j.bbadis.2024.167249
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0925443924002382
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics

1
1. scibot 03 May 2024
  
  in Public
  
  RRID:AB_2179887
  
  DOI: 10.7554/eLife.89100
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2179887
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11060712/
Sep 2023
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TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

1
1. scibot 07 Sep 2023
  
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  RRID:AB_2179887
  
  DOI: 10.1016/j.celrep.2023.113070
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2179887
  
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sciencedirect.com/science/article/pii/S2211124723010811
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis

1
1. scibot 12 Jan 2023
  
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  RRID:AB_2179887
  
  DOI: 10.1158/0008-5472.CAN-22-0834
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2179887
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9574375/
Jul 2022
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A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions

1
1. scibot 27 Jul 2022
  
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  RRID:AB_2179887
  
  DOI: 10.1016/j.xcrm.2022.100686
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2666379122002221
academic.oup.com academic.oup.com

A novel germline deletion of p.C630 in RET causes MTC and promotes cell proliferation and sensitivity to pralsetinib

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1. scibot 02 Jul 2022
  
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  AB_2179887
  
  DOI: 10.1210/clinem/dgac352
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @scibot
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac352/6605991
Apr 2021
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Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

1
1. scibot 13 Apr 2021
  
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  RRID:AB_2179887
  
  DOI: 10.1016/j.cell.2021.03.031
  
  Resource: (Cell Signaling Technology Cat# 3221, RRID:AB_2179887)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2179887
  
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  RRIDCUR:Validated RRID:AB_2179887
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S0092867421003627