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PKA-dependent phosphorylation drives stress granule maturation and controls recovery from prolonged starvation

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sciencedirect.com/science/article/pii/S2211124726008132
Jun 2026
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Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies

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Monocytic niches escape T cell surveillance and promote Mycobacterium tuberculosis persistence in lymph nodes

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Apr 2026
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Targeting tumor microenvironment-derived NRG1-HER2/3 signaling with zenocutuzumab restores sensitivity to AR inhibition in PTEN wild-type prostate cancer

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aacrjournals.org/mct/article/25/4/662/776472/Targeting-Tumor-Microenvironment-Derived-NRG1-HER2
Feb 2026
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Covalent modification of a glutamic acid inspired by HaloTag technology

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pmc.ncbi.nlm.nih.gov/articles/PMC12864978/
Dec 2025
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Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice

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sciencedirect.com:5037/science/article/pii/S1550413125005261
Oct 2025
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HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis

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sciencedirect.com/science/article/pii/S2211124725011532
Sep 2025
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OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis

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Feb 2025
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TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion

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Nov 2024
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The roles of mTORC1 in parathyroid gland function in chronic kidney disease‐induced secondary hyperparathyroidism: Evidence from male genetic mouse models and clinical data

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Aug 2024
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mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition | American Journal of Physiology-Cell Physiology

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EDC3 phosphorylation regulates growth and invasion through controlling P‐body formation and dynamics

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May 2024
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Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in Amyotrophic Lateral Sclerosis

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biorxiv.org/content/10.1101/2024.01.08.574551v1
Oct 2023
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A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit

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Aug 2023
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Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy

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Jul 2023
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GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells

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May 2023
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Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19

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Apr 2023
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Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration

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1. scibot 27 Apr 2023
  
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Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways

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Dec 2022
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Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension

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science.org/doi/10.1126/scisignal.abn2743
Nov 2022
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mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity

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nature.com/articles/s41467-022-34763-y
Aug 2022
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Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

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Jul 2022
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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function

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Jun 2022
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Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

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A single vomeronasal receptor promotes intermale aggression through dedicated hypothalamic neurons

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sciencedirect.com/science/article/pii/S089662732200410X
Nov 2021
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ajpcell.00385.2020-html.html

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52.53.155.43/fcc41b1e6a5d6b11282a20b711b4d6b99930c8bb/ajpcell.00385.2020-html.html
Jul 2021
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Untitled document

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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

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Gut-microbiota-targeted diets modulate human immune status

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cell.com/cell/fulltext/S0092-8674(21)00754-6
Jan 2021
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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Nov 2020
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Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

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Sep 2020
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Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation

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Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis

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Zonation of Pancreatic Acinar Cells in Diabetic Mice

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Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice

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sciencedirect.com/science/article/pii/S2211124720308160
Jan 2020
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Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled

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1. scibot 13 Jan 2020
  
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  RRID:AB_2181037
  
  DOI: 10.1016/j.cub.2019.06.018
  
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Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.10.001
  
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elifesciences.org elifesciences.org

Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.48003
  
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PI3K inhibitors protect against glucocorticoid-induced skin atrophy

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  DOI: 10.1016/j.ebiom.2019.01.055
  
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sciencedirect.com/science/article/pii/S2352396419300428
Nov 2018
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Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

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1. scibot 05 Nov 2018
  
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Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

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1. scibot 05 Nov 2018
  
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  RRID:AB_2181037
  
  Curator: @evieth
  
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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

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1. scibot 05 Nov 2018
  
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Untitled document

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1. scibot 05 Nov 2018
  
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academic.oup.com academic.oup.com

Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice

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1. scibot 05 Nov 2018
  
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academic.oup.com/endo/article/159/1/519/4562294
Nov 2017
elifesciences.org elifesciences.org

LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs

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1. scibot 08 Nov 2017
  
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  AB_2181037
  
  Curator: @chewbeccax
  
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Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice

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1. scibot 08 Nov 2017
  
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  Cell Signaling 4856S
  
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