81 Matching Annotations
  1. Last 7 days
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    Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms
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    biorxiv.org/content/10.64898/2026.06.24.733515v1
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC13318054/
  4. Mar 2026
  5. www.sciencedirect.com www.sciencedirect.com
    Assessing leaky expression of Cre-dependent DNA constructs in the mouse genome using sensitive bioluminescent reporters
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    sciencedirect.com/science/article/pii/S266723752600069X
  6. Feb 2026
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    Distinct spatial patterning and transcriptomic landscapes of human neural organoids by localized delivery of morphogens
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    sciencedirect.com/science/article/pii/S1934590926000317
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    De novo identification of potent ingredients for proteasome activation in MT101-5 using an AI-driven approach
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    sciencedirect.com/science/article/pii/S0753332226001265
  9. Jan 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum
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    pmc.ncbi.nlm.nih.gov/articles/PMC12829992/
  11. Dec 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Subsecond dopamine fluctuations do not specify the vigor of ongoing actions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12672363/
  13. Oct 2025
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    3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy
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    sciencedirect.com/science/article/pii/S1934590925003698
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12516900/
  16. Sep 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kappa opioid receptor antagonism restores phosphorylation, trafficking and behavior induced by a disease-associated dopamine transporter variant
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    pmc.ncbi.nlm.nih.gov/articles/PMC12436197/
  18. 52.53.155.43 52.53.155.43
    2025.08.28.672006v1.full-html.html
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    52.53.155.43/1c78deaa12ef1065bee04217bb87fcbf90d61c87/2025.08.28.672006v1.full-html.html
  19. May 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Parallel Gene Expression Changes in Ventral Midbrain Dopamine and GABA Neurons during Normal Aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12121937/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repetitive prefrontal tDCS activates VTA dopaminergic neurons, resulting in attenuation of Alzheimer’s Disease-like deficits in Tg2576 mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12039073/
  22. Apr 2025
  23. www.sciencedirect.com www.sciencedirect.com
    Early A-synuclein aggregation decreases corticostriatal glutamate drive and synapse density
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    sciencedirect.com/science/article/pii/S0969996125001342
  24. Feb 2025
  25. 52.53.155.43 52.53.155.43
    awaf051-html.html
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    52.53.155.43/ad3dfd72e4bbedea4b2fe45e2acb356095b82879/awaf051-html.html
  26. Dec 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dopamine D2 Receptors in the Paraventricular Thalamus Attenuate Cocaine Locomotor Sensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC5654238/
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    Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders
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    sciencedirect.com/science/article/pii/S2211124724013482
  29. Oct 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Voluntary exercise suppresses inflammation and improves insulin resistance in the arcuate nucleus and ventral tegmental area in mice on a high-fat diet
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    sciencedirect.com/science/article/pii/S0031938424002518
  31. Aug 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease gene, Synaptojanin1, dysregulates the surface maintenance of the dopamine transporter
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310474/
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization of a new low‐dose 6‐hydroxydopamine model of Parkinson's disease in rat
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23708/full
  34. Jul 2024
  35. www.sciencedirect.com www.sciencedirect.com
    An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
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    sciencedirect.com/science/article/pii/S2211124724008386
  36. Apr 2024
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Anti-manic effect of deep brain stimulation of the ventral tegmental area in an animal model of mania induced by methamphetamine
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    onlinelibrary.wiley.com/doi/10.1111/bdi.13423
  38. Oct 2023
  39. www.cell.com www.cell.com
    Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease
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    cell.com/cell-reports/abstract/S2211-1247(23)01082-3
  40. Jul 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10336101/
  42. May 2023
  43. www.biorxiv.org www.biorxiv.org
    Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences
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    biorxiv.org/content/10.1101/2023.05.03.539310v1
  44. Apr 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain
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    sciencedirect.com/science/article/pii/S088915912300106X
  46. Jan 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cocaine-regulated trafficking of dopamine transporters in cultured neurons revealed by a pH sensitive reporter
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    ncbi.nlm.nih.gov/pmc/articles/PMC9804146/
  48. Nov 2022
  49. link.springer.com link.springer.com
    Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice
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    link.springer.com/article/10.1186/s13024-022-00580-6
  50. Sep 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity
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    sciencedirect.com/science/article/pii/S2211124722012724
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammation in VTA Caused by HFD Induces Activation of Dopaminergic Neurons Accompanied by Binge-like Eating
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    ncbi.nlm.nih.gov/pmc/articles/PMC9502544/
  53. www.nature.com www.nature.com
    Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters
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    nature.com/articles/s41380-022-01773-7
  54. Apr 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabinoid receptor 1 is required for neurodevelopment of striosome-dendron bouquets
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    ncbi.nlm.nih.gov/pmc/articles/PMC9007419/
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LRRK2-G2019S mice display alterations in glutamatergic synaptic transmission in midbrain dopamine neurons
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15588
  57. Feb 2022
  58. link.springer.com link.springer.com
    CDNF and MANF regulate ER stress in a tissue-specific manner
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    link.springer.com/article/10.1007/s00018-022-04157-w
  59. Nov 2021
  60. link.springer.com link.springer.com
    Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein
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    link.springer.com/article/10.1186/s40478-021-01283-7
  61. Oct 2021
  62. www.sciencedirect.com www.sciencedirect.com
    TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
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    sciencedirect.com/science/article/pii/S0896627321007042
  63. Aug 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5980712/
  65. link.springer.com link.springer.com
    27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
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    link.springer.com/article/10.1186/s12868-018-0420-5
  66. bmcneurosci.biomedcentral.com bmcneurosci.biomedcentral.com
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    bmcneurosci.biomedcentral.com/articles/10.1186/s12868-018-0420-5
  67. www.eneuro.org www.eneuro.org
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    eneuro.org/content/4/5/ENEURO.0227-17.2017
  68. Jul 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6240015/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5340420/
  71. link.springer.com link.springer.com
    27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
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    link.springer.com/article/10.1186/s12868-018-0420-5
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24230
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.23708
  74. Jun 2021
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15432
  76. elifesciences.org elifesciences.org
    Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum
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    elifesciences.org/articles/68041
  77. Apr 2021
  78. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
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    sciencedirect.com/science/article/pii/S0092867421003792
  79. Mar 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC7916783/
  81. Feb 2021
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Catecholaminergic Innervation of Periventricular Neurogenic Regions of the Developing Mouse Brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC7538673/
  83. Jan 2021
  84. link.springer.com link.springer.com
    Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3a m−/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A 2A Receptor Blockade
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    link.springer.com/article/10.1007/s12035-020-02275-9
  85. Dec 2020
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ascorbate deficiency decreases dopamine release in gulo–/– and APP/PSEN1 mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15151
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Heterogeneous expression of dopaminergic markers and Vglut2 in mouse meso‐diencephalic dopaminergic nuclei A8‐A13
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    onlinelibrary.wiley.com/doi/10.1002/cne.25020
  88. Sep 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
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    sciencedirect.com/science/article/pii/S0092867420302865
  90. www.sciencedirect.com www.sciencedirect.com
    Catecholaminergic axons in the neocortex of adult mice regrow following brain injury
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    sciencedirect.com/science/article/pii/S0014488619302365
  91. www.jneurosci.org www.jneurosci.org
    A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins
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    jneurosci.org/content/40/1/107
  92. www.sciencedirect.com www.sciencedirect.com
    Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System
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    sciencedirect.com/science/article/pii/S2211124720302667
  93. www.eneuro.org www.eneuro.org
    MANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine system
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    eneuro.org/content/7/1/ENEURO.0477-19.2019
  94. Jan 2020
  95. www.mdpi.com www.mdpi.com
    Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures
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    mdpi.com/1422-0067/20/12/2901/htm
  96. link.springer.com link.springer.com
    Neuronal Trans-differentiation by Transcription Factors Ascl1 and Nurr1: Induction of a Dopaminergic Neurotransmitter Phenotype in Cortical GABAergic Neurons
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    link.springer.com/article/10.1007/s12035-019-01701-x
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    Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
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    sciencedirect.com/science/article/pii/S2211124719312069
  98. www.sciencedirect.com www.sciencedirect.com
    Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning
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    sciencedirect.com/science/article/pii/S2211124719308812
  99. www.sciencedirect.com www.sciencedirect.com
    Cerebral dopamine Neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice
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    sciencedirect.com/science/article/pii/S0969996119303717
  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Viral vector‐mediated Cre recombinase expression in substantia nigra induces lesions of the nigrostriatal pathway associated with perturbations of dopamine‐related behaviors and hallmarks of programmed cell death
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14684
  101. Nov 2018
  102. academic.oup.com academic.oup.com
    High Sensitivity Mapping of Cortical Dopamine D2 Receptor Expressing Neurons
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    academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhy261/5122732
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC6019446/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC6014061/
  105. www.jneurosci.org www.jneurosci.org
    Region-Specific Regulation of Presynaptic Dopamine Homeostasis by D2 Autoreceptors Shapes the In Vivo Impact of the Neuropsychiatric Disease-Associated DAT Variant Val559
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    jneurosci.org/content/38/23/5302
  106. www.sciencedirect.com www.sciencedirect.com
    Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders
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    sciencedirect.com/science/article/pii/S2352396418301622
  107. www.ebiomedicine.com www.ebiomedicine.com
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    ebiomedicine.com/article/S2352-3964(18)30162-2/abstract
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter
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    ncbi.nlm.nih.gov/pmc/articles/PMC5896956/
  109. link.springer.com link.springer.com
    27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
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    link.springer.com/article/10.1186/s12868-018-0420-5
  110. Nov 2017
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5654238/
  112. www.jneurosci.org www.jneurosci.org
    The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism
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    jneurosci.org/content/37/38/9288
  113. www.nature.com www.nature.com
    Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease
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    nature.com/articles/ncomms14727
  114. www.sciencedirect.com www.sciencedirect.com
    Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons
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    sciencedirect.com/science/article/pii/S0896627317300430
  115. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efferent Pathways of the Mouse Lateral Habenula
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    pmc.ncbi.nlm.nih.gov/articles/PMC4232452/