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Hydrogen sulfide ameliorates peritoneal fibrosis: inhibition of high mobility group box-1 expression to block the activation of the transforming growth factor-beta/Smad3 pathway

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  AB_2193182
  
  DOI: 10.4103/mgr.MEDGASRES-D-25-00048
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12413889/
Jul 2025
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Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer

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  DOI: 10.1186/s12964-025-02337-2
  
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TFE3-splicing factor fusions represent functional drivers and druggable targets in translocation renal cell carcinoma

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1. scibot 08 Jul 2025
  
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  DOI: 10.1158/0008-5472.CAN-23-1789
  
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aacrjournals.org/cancerres/article/84/8/1286/742985/TFE3-Splicing-Factor-Fusions-Represent-Functional
May 2025
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Microbial metabolite ammonia disrupts TGF-β signaling to promote colon cancer

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.jbc.2025.108559
  
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sciencedirect.com/science/article/pii/S0021925825004089
Apr 2025
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A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells

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1. scibot 17 Apr 2025
  
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  DOI: 10.1096/fj.202403146RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202403146RR
Mar 2025
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ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma

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1. scibot 29 Mar 2025
  
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The impact and mechanisms of YL-IPA08, a potent ligand for the translocator protein (18 kDa) on protection against LPS-induced depression and cognitive dysfunction in rodents

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1. scibot 11 Mar 2025
  
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  DOI: 10.1007/s11011-025-01565-2
  
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link.springer.com/article/10.1007/s11011-025-01565-2
Feb 2025
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LRRC75A-AS1 drives the epithelial-mesenchymal transition in cervical cancer by binding IGF2BP1 and inhibiting SYVN1-mediated NLRP3 ubiquitination

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1. scibot 14 Feb 2025
  
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aacrjournals.org/mcr/article/22/12/1075/750095/LRRC75A-AS1-Drives-the-Epithelial-Mesenchymal
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TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

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1. scibot 13 Feb 2025
  
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  AB_2193182
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
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1-s2.0-S000293782500064X-main-html.html

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1. scibot 04 Feb 2025
  
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  AB_2193182
  
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52.53.155.43/9c52bf7167f98dc0e4e04eb899abb8d90b663a21/1-s2.0-S000293782500064X-main-html.html
Jan 2025
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Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation

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1. scibot 31 Jan 2025
  
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  DOI: 10.1016/j.isci.2025.111756
  
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sciencedirect.com/science/article/pii/S258900422500015X
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ERBB4 selectively amplifies TGF-β pro-metastatic responses

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1. scibot 24 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115210
  
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sciencedirect.com/science/article/pii/S2211124724015614
Nov 2024
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p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb

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1. scibot 21 Nov 2024
  
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  DOI: 10.1038/s44318-024-00246-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
Sep 2024
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Global isonicotinylome analysis identified SMAD3 isonicotinylation promotes liver cancer cell epithelial–mesenchymal transition and invasion

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1. scibot 25 Sep 2024
  
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  AB_2193182
  
  DOI: 10.1016/j.isci.2024.110775
  
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sciencedirect.com/science/article/pii/S2589004224020005
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Aldehydes alter TGF-β signaling and induce obesity and cancer

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  AB_2193182
  
  DOI: 10.1016/j.celrep.2024.114676
  
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sciencedirect.com/science/article/pii/S2211124724010271
Jul 2024
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Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice

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1. scibot 18 Jul 2024
  
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  AB_2193182
  
  DOI: 10.1210/endocr/bqae069
  
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dx.doi.org/10.1210/endocr/bqae069
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RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential

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1. scibot 07 Jul 2024
  
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  DOI: 10.1158/1541-7786.MCR-23-0512
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10841372/
May 2024
52.53.155.43 52.53.155.43

mcr-23-0478-html.html

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1. scibot 23 May 2024
  
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52.53.155.43/a4d1b1195ce648b46cbdc2b7d1e41b22ba16f57e/mcr-23-0478-html.html
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Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging

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1. scibot 08 May 2024
  
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  DOI: 10.1016/j.isci.2024.109708
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11066433/
Apr 2024
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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

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1. scibot 24 Apr 2024
  
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  DOI: 10.1093/narcan/zcae018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
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mcr-23-0478-html.html

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52.53.155.43/a4d1b1195ce648b46cbdc2b7d1e41b22ba16f57e/mcr-23-0478-html.html
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Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women with Repeated Implantation Failure

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  DOI: 10.1210/endocr/bqae002
  
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academic.oup.com/endo/article-abstract/165/3/bqae002/7513513
Feb 2024
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Stromal-derived MAOB promotes prostate cancer growth and progression

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1. scibot 14 Feb 2024
  
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  DOI: 10.1126/sciadv.adi4935
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
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EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

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sciencedirect.com/science/article/pii/S2211124724000421
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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

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1. scibot 09 Feb 2024
  
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  RRID:AB_2193182
  
  DOI: 10.1101/2023.12.05.570182
  
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  DOI: 10.1101/2023.12.05.570182
  
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biorxiv.org/content/10.1101/2023.12.05.570182v1
Jan 2024
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Transforming growth factor-β1 protects against white matter injury and reactive astrogliosis via the p38 MAPK pathway in rodent demyelinating model

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  DOI: 10.1111/jnc.16037
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16037
Dec 2023
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Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling

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  DOI: 10.1016/j.devcel.2023.11.020
  
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sciencedirect.com/science/article/pii/S1534580723006184
Nov 2023
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CD4+LAG3+T cells are decreased in SSc-ILD and affects fibroblast mesenchymal transition by TGF-β3

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  DOI: 10.1016/j.isci.2023.108225
  
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52.53.155.43/5ad643fa5a560812951901941b13e2151ba1a6c6/1-s2.0-S2589004223023027-main-html.html
Oct 2023
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Human microglial state dynamics in Alzheimer’s disease progression

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  DOI: 10.1016/j.cell.2023.08.037
  
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sciencedirect.com/science/article/pii/S0092867423009716
www.cmghjournal.org www.cmghjournal.org

Hepatocyte FoxO1 deficiency protects from liver fibrosis via reducing inflammation and TGF-β1 mediated HSC activation

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  DOI: 10.1016/j.jcmgh.2023.08.013
  
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cmghjournal.org/article/S2352-345X(23)00161-3/abstract
Sep 2023
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ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer

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1. scibot 20 Sep 2023
  
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  DOI: 10.1158/0008-5472.CAN-23-0067
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10502452/
Aug 2023
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CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112936
  
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sciencedirect.com/science/article/pii/S2211124723009476
Jul 2023
52.53.155.43 52.53.155.43

can-23-0067-html.html

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1. scibot 08 Jul 2023
  
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5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling

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Epithelial cells activate fibroblasts to promote esophageal cancer development

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Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex

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Targeting activin receptor-like kinase 7 ameliorates adiposity and associated metabolic disorders

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Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer

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TGFBR3 supports anoikis through suppressing ATF4 signaling

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Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

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Peritoneal Restoration by Repurposing Vitamin D Inhibits Ovarian Cancer Dissemination via Blockade of the TGF-β1/Thrombospondin-1 Axis

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PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II

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Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway

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Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

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Effect of miR-183-5p on Cholestatic Liver Fibrosis by Regulating Fork Head Box Protein O1 Expression

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Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

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Adrenomedullin ameliorates pulmonary fibrosis by regulating TGF-β-Smads signaling and myofibroblast differentiation

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TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

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SMAD-dependent signaling mediates BMP6-induced stimulation of connective tissue growth factor in luteinized human granulosa cells

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Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation

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TNAP is a novel regulator of cardiac fibrosis after myocardial infarction by mediating TGF-β/Smads and ERK1/2 signaling pathways

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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

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PRMT1-p53 Pathway Controls Epicardial EMT and Invasion

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The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity

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PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

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DNA Damage Activates TGF-β Signaling via ATM-c-Cbl-Mediated Stabilization of the Type II Receptor TβRII

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Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways

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Bone morphogenetic protein 2 promotes human trophoblast cell invasion by inducing activin A production

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Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression

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europepmc.org/articles/PMC5731821/
www.sciencedirect.com www.sciencedirect.com

Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer

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1. scibot 05 Nov 2018
  
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  RRID:AB_2193182
  
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  (Cell Signaling Technology Cat# 9523, RRID:AB_2193182)
  
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sciencedirect.com/science/article/pii/S1534580717308717
Nov 2017
academic.oup.com academic.oup.com

TGF-β1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression

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1. scibot 08 Nov 2017
  
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  AB_2193182
  
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academic.oup.com/endo/article/158/10/3620/3988140/TGF-1-Inhibits-Human-Trophoblast-Cell-Invasion-by
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PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism

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1. scibot 08 Nov 2017
  
  in Public
  
  AB_2193182
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1550413117301638

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