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3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.stem.2025.10.001
  
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sciencedirect.com/science/article/pii/S1934590925003698
Oct 2025
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Hypoxia promotes airway differentiation in the human lung epithelium

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.stem.2025.09.007
  
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sciencedirect.com/science/article/pii/S1934590925003388
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Single-cell exploration of gonadal somatic cell lineage specification during human sex determination

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.devcel.2025.09.011
  
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sciencedirect.com/science/article/pii/S1534580725005714
Sep 2025
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Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

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1. scibot 27 Sep 2025
  
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  DOI: 10.7554/eLife.100687
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12463392/
Aug 2025
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Loss of miR-9-2 Causes Cerebral Hemorrhage and Hydrocephalus by Widespread Disruption of Cell-Type-Specific Neurodevelopmental Gene Networks.

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1. scibot 09 Aug 2025
  
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  DOI: 10.1101/2025.07.31.668014
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12324547/
May 2025
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GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.neuron.2025.04.033
  
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sciencedirect.com/science/article/pii/S0896627325003459
Mar 2025
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Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

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  DOI: 10.1038/s41467-025-57684-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11929771/
Dec 2024
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Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate

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1. scibot 12 Dec 2024
  
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Cell competition drives bronchiolization and pulmonary fibrosis

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1. scibot 11 Dec 2024
  
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  DOI: 10.1038/s41467-024-54997-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11621346/
Sep 2024
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Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response

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1. scibot 10 Sep 2024
  
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sciencedirect.com/science/article/pii/S2211124724010702
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Chemogenetic activation of ventral medullary astrocytes enhances feeding and corticosterone release in response to mild glucoprivation

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1. scibot 06 Sep 2024
  
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  DOI: 10.1152/ajpregu.00079.2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10396275/
Aug 2024
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Host circuit engagement of human cortical organoids transplanted in rodents

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  DOI: 10.1038/s41596-024-01029-4
  
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nature.com/articles/s41596-024-01029-4
Jun 2024
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Direct comparison of Hoxb8-driven reporter distribution in the brains of four transgenic mouse lines: towards a spinofugal projection atlas

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1. scibot 02 Jun 2024
  
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  DOI: 10.3389/fnana.2024.1400015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11137224/
May 2024
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Cell competition drives bronchiolization and pulmonary fibrosis

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1. scibot 23 May 2024
  
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  DOI: 10.21203/rs.3.rs-4177351/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11092845/
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Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury

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1. scibot 05 May 2024
  
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  DOI: 10.1016/j.celrep.2021.108889
  
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sciencedirect.com/science/article/pii/S2211124721002035
Feb 2024
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SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

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1. scibot 16 Feb 2024
  
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  DOI: 10.7554/eLife.95577
  
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elifesciences.org/articles/95577
Dec 2023
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A tridimensional atlas of the developing human head

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.013
  
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  DOI: 10.1016/j.cell.2023.11.013
  
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sciencedirect.com/science/article/pii/S0092867423012308
Oct 2023
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Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.108037
  
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sciencedirect.com/science/article/pii/S2589004223021144
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Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling

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1. scibot 12 Oct 2023
  
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  DOI: 10.1101/2023.07.13.548459
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
Jul 2023
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Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112841
  
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sciencedirect.com/science/article/pii/S2211124723008525
Jun 2023
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Higher temperatures directly increase germ cell number, promoting feminization of red-eared slider turtles

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  DOI: 10.1016/j.cub.2023.06.008
  
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sciencedirect.com/science/article/pii/S0960982223007583
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Sox9 regulates melanocytic fate decision of adult hair follicle stem cells

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  DOI: 10.1016/j.isci.2023.106919
  
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sciencedirect.com/science/article/pii/S2589004223009963
May 2023
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Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture

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  DOI: 10.1016/j.cell.2023.04.019
  
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sciencedirect.com/science/article/pii/S0092867423004154
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Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis

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  DOI: 10.3390/ijms23095265
  
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mdpi.com/1422-0067/23/9/5265/htm
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain

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  DOI: 10.1016/j.isci.2023.106242
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10006693/
Jan 2023
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Evolutionary assembly and disassembly of the mammalian sternum

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  DOI: 10.1016/j.cub.2022.11.055
  
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Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation

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  DOI: 10.1016/j.celrep.2022.111942
  
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sciencedirect.com/science/article/pii/S2211124722018435
Dec 2022
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SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice

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  DOI: 10.1016/j.celrep.2022.111842
  
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sciencedirect.com/science/article/pii/S221112472201734X
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Astrocyte heterogeneity within white matter tracts and a unique subpopulation of optic nerve head astrocytes

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  DOI: 10.1016/j.isci.2022.105568
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9708923/
Nov 2022
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mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity

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1. scibot 29 Nov 2022
  
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  DOI: 10.1038/s41467-022-34763-y
  
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nature.com/articles/s41467-022-34763-y
onlinelibrary.wiley.com onlinelibrary.wiley.com

Brain injury triggers cell-type-specific and time-dependent endoplasmic reticulum stress responses

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1. scibot 24 Nov 2022
  
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  DOI: 10.1002/glia.24303
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24303
Aug 2022
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Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids

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1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.xpro.2022.101656
  
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sciencedirect.com/science/article/pii/S2666166722005366
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Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells

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1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.diff.2022.08.001
  
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sciencedirect.com/science/article/pii/S0301468122000627
journals.plos.org journals.plos.org

Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions

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1. scibot 31 Aug 2022
  
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  DOI: 10.1371/journal.pbio.3001759
  
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journals.plos.org/plosbiology/article
Jun 2022
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R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.devcel.2022.05.010
  
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Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene

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Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting

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An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function

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Identification of a discrete subpopulation of spinal cord ependymal cells with neural stem cell properties

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Suspension culture promotes serosal mesothelial development in human intestinal organoids

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Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity

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Light microscopic and heterogeneity analysis of astrocytes in the common marmoset brain

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Experience-dependent myelination following stress is mediated by the neuropeptide dynorphin

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Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors

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Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

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Oestrogen signalling drives ciliogenesis in human endometrial organoids

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Meis1 coordinates cerebellar granule cell development by regulating Pax6 transcription, BMP signaling and Atoh1 degradation.

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Yap and its subcellular localization have distinct compartment-specific roles in the developing lung

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Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration

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Charting human development using a multi-endodermal organ atlas and organoid models

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GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration

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Fibroblast dedifferentiation as a determinant of successful regeneration

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Transcriptomic and epigenetic preservation of genetic sex identity in estrogen-feminized male chicken embryonic gonads

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Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

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The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

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Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells

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A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors

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Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury

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DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

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HIFα regulates developmental myelination independent of autocrine Wnt signaling

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ApoE isoform-dependent SARS-CoV-2 neurotropism and cellular response

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Rab6A as a Pan-Astrocytic Marker in Mouse and Human Brain, and Comparison with Other Glial Markers (GFAP, GS, Aldh1L1, SOX9)

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Dentate gyrus development requires a cortical hem-derived astrocytic scaffold

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Sep 2020
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Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

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A new genetic strategy for targeting microglia in development and disease

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Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis

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Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities

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A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells

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Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal

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Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation

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Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

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3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling

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Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

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SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

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YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis

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