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Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity

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sciencedirect.com/science/article/pii/S2211124726000549
Dec 2025
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Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

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1. scibot 10 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.015
  
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sciencedirect.com:5037/science/article/pii/S009286742501311X
Jul 2025
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TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC

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cell.com/cell-reports/abstract/S2211-1247(25)00743-0
Jun 2025
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Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy

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1. scibot 03 Jun 2025
  
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sciencedirect.com/science/article/pii/S1074761325002274
Mar 2025
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IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis

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cell.com/immunity/fulltext/S1074-7613(25)00073-1
Jan 2025
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Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation

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sciencedirect.com/science/article/pii/S2211124724015559
Aug 2024
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Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

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ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
Jul 2024
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A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1

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sciencedirect.com/science/article/pii/S1931312824002622
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Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts

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ncbi.nlm.nih.gov/pmc/articles/PMC11295714/
Feb 2024
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The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes

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1. scibot 29 Feb 2024
  
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sciencedirect.com/science/article/pii/S2211124724001414
Jan 2024
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Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.12.005
  
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sciencedirect.com/science/article/pii/S153458072300655X
Dec 2023
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Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108620
  
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sciencedirect.com/science/article/pii/S2589004223026974
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SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113506
  
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sciencedirect.com/science/article/pii/S2211124723015188
Jul 2023
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GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107341
  
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sciencedirect.com/science/article/pii/S2589004223014189
Jun 2023
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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.06.002
  
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sciencedirect.com/science/article/pii/S1074761323002376
Nov 2022
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Asebogenin Suppresses Thrombus Formation via Inhibition of Syk Phosphorylation

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1. scibot 20 Nov 2022
  
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  DOI: 10.1111/bph.15964
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15964
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CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.10.015
  
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sciencedirect.com/science/article/pii/S1535610822005062
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Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia

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1. scibot 09 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111614
  
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sciencedirect.com/science/article/pii/S2211124722014838
Sep 2022
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Pentacyclic triterpenoid ursolic acid interferes with mast cell activation via a lipid-centric mechanism affecting FcεRI signalosome functions

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1. scibot 16 Sep 2022
  
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  DOI: 10.1016/j.jbc.2022.102497
  
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sciencedirect.com/science/article/pii/S0021925822009401
Jul 2022
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Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111128
  
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sciencedirect.com/science/article/pii/S2211124722009342
Jun 2022
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BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors

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1. scibot 29 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.111019
  
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sciencedirect.com/science/article/pii/S2211124722008087
Mar 2022
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Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation

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  DOI: 10.1016/j.celrep.2022.110567
  
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sciencedirect.com/science/article/pii/S2211124722003114
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CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors

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1. scibot 26 Mar 2022
  
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  DOI: 10.1016/j.chom.2017.04.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8938989/
Feb 2022
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Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion

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1. scibot 23 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110414
  
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sciencedirect.com/science/article/pii/S2211124722001383
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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

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sciencedirect.com/science/article/pii/S1535610822000058
Aug 2021
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Untitled document

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  DOI: 10.1016/j.ccell.2017.03.001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5389883/
Feb 2021
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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.immuni.2018.12.020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6382412/
Sep 2020
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Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway

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1. scibot 15 Sep 2020
  
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  DOI: 10.1016/j.bcp.2020.113949
  
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sciencedirect.com/science/article/pii/S0006295220301775
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A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies

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  DOI: 10.1111/bph.14809
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14809
Jan 2020
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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.056
  
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sciencedirect.com/science/article/pii/S2211124719303869
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Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells

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  DOI: 10.1016/j.celrep.2018.11.096
  
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sciencedirect.com/science/article/pii/S2211124718318874
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  DOI: 10.1016/j.cmet.2019.02.002
  
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sciencedirect.com/science/article/pii/S155041311930066X
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  DOI: 10.1016/j.immuni.2018.12.020
  
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sciencedirect.com/science/article/pii/S1074761318305685
Nov 2018
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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S107476131830387X
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Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

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1. scibot 05 Nov 2018
  
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RRID:AB_2197222

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scibot

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cell.com/cell-stem-cell/fulltext/S1934-5909(18)30284-4
europepmc.org europepmc.org

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2197222
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2710, RRID:AB_2197222)
  
  SciCrunch record: RRID:AB_2197222
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2197222
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europepmc.org/articles/PMC5608509/
Nov 2017
academic.oup.com academic.oup.com

Aldose Reductase Mediates NLRP3 Inflammasome–Initiated Innate Immune Response in Hyperglycemia-Induced Thp1 Monocytes and Male Mice

1
1. scibot 09 Nov 2017
  
  in Public
  
  AB_2197222
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2710, RRID:AB_2197222)
  
  SciCrunch record: RRID:AB_2197222
  
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  RRID:AB_2197222
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academic.oup.com/endo/article/158/10/3661/4049499/Aldose-Reductase-Mediates-NLRP3-Inflammasome
www.sciencedirect.com www.sciencedirect.com

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

1
1. scibot 08 Nov 2017
  
  in Public
  
  anti-phospho S6KCell Signaling TechnologiesCat# 2710
  
  Curator: @Jmenke
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2710, RRID:AB_2197222)
  
  SciCrunch record: RRID:AB_2197222
  
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  RRID:AB_2197222 RRIDCUR:Missing
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RRIDCUR:Missing

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sciencedirect.com/science/article/pii/S0092867417308309
www.sciencedirect.com www.sciencedirect.com

CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2197222
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2710, RRID:AB_2197222)
  
  SciCrunch record: RRID:AB_2197222
  
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  RRID:AB_2197222 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1931312817301518
www.sciencedirect.com www.sciencedirect.com

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2197222
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2710, RRID:AB_2197222)
  
  SciCrunch record: RRID:AB_2197222
  
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  RRID:AB_2197222 RRIDCUR:Validated
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RRID:AB_2197222

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sciencedirect.com/science/article/pii/S1535610817300636