94 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication
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    1. scibot 14 Jul 2024
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      DOI: 10.1016/j.isci.2024.110144

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    ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
  3. Jun 2024
  4. www.sciencedirect.com www.sciencedirect.com
    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.immuni.2024.05.017

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    sciencedirect.com/science/article/pii/S1074761324002711
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    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
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    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114289

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    sciencedirect.com/science/article/pii/S221112472400617X
  6. May 2024
  7. aacrjournals.org aacrjournals.org
    TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity
    2
    1. scibot 23 May 2024
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      DOI: 10.1158/2159-8290.CD-23-0700

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    2. scibot 23 May 2024
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      DOI: 10.1158/2159-8290.CD-23-0700

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    aacrjournals.org/cancerdiscovery/article/14/5/752/745044/TREX1-Inactivation-Unleashes-Cancer-Cell-STING
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    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.cell.2024.04.025

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    sciencedirect.com/science/article/pii/S0092867424004513
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    Trophoblastic signals facilitate endometrial interferon response and lipid metabolism, ensuring normal decidualization
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    1. scibot 21 May 2024
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      DOI: 10.1016/j.celrep.2024.114246

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    sciencedirect.com/science/article/pii/S2211124724005746
  10. www.biorxiv.org www.biorxiv.org
    Viral mimicry and memory deficits upon microglial deletion of ATRX
    1
    1. scibot 16 May 2024
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      DOI: 10.1101/2024.05.07.592875

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    biorxiv.org/content/10.1101/2024.05.07.592875v1
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atherosis-associated lnc_000048 activates PKR to enhance STAT1-mediated polarization of THP-1 macrophages to M1 phenotype
    1
    1. scibot 15 May 2024
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      DOI: 10.4103/NRR.NRR-D-23-01355

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    ncbi.nlm.nih.gov/pmc/articles/PMC11090429/
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    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
    2
    1. scibot 01 May 2024
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      DOI: 10.1016/j.celrep.2024.113942

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      DOI: 10.1016/j.celrep.2024.113942

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    ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
  13. Apr 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C
    1
    1. scibot 29 Apr 2024
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      DOI: 10.1016/j.isci.2024.109704

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046299/
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    Inhibition of Pim kinases triggers a broad antiviral activity by affecting innate immunity and via the PI3K-Akt-mTOR axis the endolysosomal system
    1
    1. scibot 23 Apr 2024
      Cell Signaling, 9172S

      DOI: 10.1016/j.antiviral.2024.105891

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    sciencedirect.com/science/article/pii/S0166354224001001
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
    1
    1. scibot 19 Apr 2024
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    sciencedirect.com/science/article/pii/S221112472400442X
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    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
    1
    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114111

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    sciencedirect.com/science/article/pii/S221112472400439X
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101498

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    sciencedirect.com/science/article/pii/S2666379124001666
  19. Mar 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
    2
    1. scibot 15 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
  21. Feb 2024
  22. www.sciencedirect.com www.sciencedirect.com
    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113831

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    sciencedirect.com/science/article/pii/S2211124724001591
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription
    1
    1. scibot 27 Feb 2024
      Cell Signaling9172S

      DOI: 10.1016/j.celrep.2024.113816

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    ncbi.nlm.nih.gov/pmc/articles/PMC11056844/
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    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
    1
    1. scibot 16 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001207
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    Balancing macrophage polarization via stem cell-derived apoptotic bodies for diabetic wound healing
    1
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.medj.2024.01.006

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    sciencedirect.com/science/article/pii/S2666634024000369
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    Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs
    1
    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113751

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    sciencedirect.com/science/article/pii/S2211124724000792
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alleviation of monocyte exhaustion by BCG derivative mycolic acid
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108978

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845070/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
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      DOI: 10.1158/1078-0432.CCR-23-0215

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524955/
  29. Jan 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells
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      DOI: 10.1016/j.celrep.2023.113600

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    ncbi.nlm.nih.gov/pmc/articles/PMC10989277/
  31. Dec 2023
  32. www.sciencedirect.com www.sciencedirect.com
    PIM kinases regulate early human Th17 cell differentiation
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      DOI: 10.1016/j.celrep.2023.113469

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    sciencedirect.com/science/article/pii/S221112472301481X
  33. Nov 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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    1. scibot 30 Nov 2023
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      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
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    PTIR1 acts as an isoform of DDX58 and promotes tumor immune resistance through activation of UCHL5
    1
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    sciencedirect.com/science/article/pii/S2211124723014006
  36. Sep 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
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      DOI: 10.1016/j.devcel.2023.08.013

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    sciencedirect.com/science/article/pii/S1534580723004094
  38. Aug 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response
    1
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      DOI: 10.1016/j.isci.2023.107631

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    sciencedirect.com/science/article/pii/S258900422301708X
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages
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      DOI: 10.1126/sciimmunol.abo4767

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    ncbi.nlm.nih.gov/pmc/articles/PMC10443087/
  41. 52.53.155.43 52.53.155.43
    ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer
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    52.53.155.43/5c44b570825d260ed49e3beddaa9d47779a57883/PIIS2211124723009488-html.html
  42. 52.53.155.43 52.53.155.43
    Journal of Neurochemistry - 2023 - Kamte-html.html
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    52.53.155.43/8cb485a49ceb78e16481f91948fc91a6dba16017/Journal of Neurochemistry - 2023 - Kamte-html.html
  43. Jun 2023
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    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
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    sciencedirect.com/science/article/pii/S0092867423005913
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    Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
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    sciencedirect.com/science/article/pii/S0092867423005779
  46. 52.53.155.43 52.53.155.43
    Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling
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  47. May 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway
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      DOI: 10.1016/j.celrep.2023.112508

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    sciencedirect.com/science/article/pii/S2211124723005193
  49. Apr 2023
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    Urea cycle activation triggered by host-microbiota maladaptation driving colorectal tumorigenesis
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      DOI: 10.1016/j.cmet.2023.03.003

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    sciencedirect.com/science/article/pii/S1550413123000815
  51. Jan 2023
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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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      DOI: 10.1016/j.ccell.2022.12.008

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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential roles of type I interferon signaling in tumor versus host cells in experimental glioma models
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  54. Dec 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    Mitochondrial cristae architecture protects against mtDNA release and inflammation
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
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  58. Nov 2022
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    The target antigen determines the mechanism of acquired resistance to T cell-based therapies
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  60. Sep 2022
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    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
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    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  63. Aug 2022
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    STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
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    The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging
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  66. Jun 2022
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    Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction
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  68. May 2022
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    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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  71. Mar 2022
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTPN2 elicits cell autonomous and non–cell autonomous effects on antitumor immunity in triple-negative breast cancer
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    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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    Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
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  76. Feb 2022
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-27/IL-27RA signaling may modulate inflammation and progression of benign prostatic hyperplasia via suppressing the LPS/TLR4 pathway
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    Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo
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  79. Jan 2022
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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  82. Dec 2021
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    MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase
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  84. Nov 2021
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    Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium
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    IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation
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  87. Aug 2021
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    CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions
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    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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  91. Jul 2021
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    Interleukin 35 ameliorates myocardial ischemia‐reperfusion injury by activating the gp130‐STAT3 axis
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    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
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  94. Jun 2021
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    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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    Translation stress and collided ribosomes are co-activators of cGAS
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  97. May 2021
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    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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    Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses
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    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
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    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
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    Regulation of Anion Channel LRRC8 Volume-Regulated Anion Channels in Transport of 2′3′-Cyclic GMP–AMP and Cisplatin under Steady State and Inflammation
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    Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates
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  106. Apr 2021
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    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
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  108. Mar 2021
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    Endogenous retrovirus expression activates type-I interferon signaling in an experimental mouse model of mesothelioma development
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      DOI: 10.1016/j.canlet.2021.03.004

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  110. Feb 2021
  111. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  112. www.mdpi.com www.mdpi.com
    Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes
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      DOI: 10.3390/antiox10020334

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching
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      DOI: 10.1016/j.immuni.2020.06.023

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  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Downregulation of uPAR promotes urokinase translocation into the nucleus and epithelial to mesenchymal transition in neuroblastoma
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      DOI: 10.1002/jcp.29555

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  115. Sep 2020
  116. www.sciencedirect.com www.sciencedirect.com
    Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
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  117. www.sciencedirect.com www.sciencedirect.com
    Decoding the Transcriptional Response to Ischemic Stroke in Young and Aged Mouse Brain
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      DOI: 10.1016/j.celrep.2020.107777

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    sciencedirect.com/science/article/pii/S2211124720307579
  118. Jan 2020
  119. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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      RRID:AB_2198289

      DOI: 10.1016/j.immuni.2019.06.007

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  120. elifesciences.org elifesciences.org
    CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity
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      DOI: 10.7554/eLife.46012

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  121. www.sciencedirect.com www.sciencedirect.com
    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
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      DOI: 10.1016/j.ccell.2018.10.006

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  122. www.sciencedirect.com www.sciencedirect.com
    IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties
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      DOI: 10.1016/j.cmet.2019.01.006

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  123. www.sciencedirect.com www.sciencedirect.com
    Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING
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    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.molcel.2019.02.038

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    sciencedirect.com/science/article/pii/S1097276519301492
  124. Nov 2018
  125. www.sciencedirect.com www.sciencedirect.com
    Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
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    sciencedirect.com/science/article/pii/S1535610818301223
  126. www.sciencedirect.com www.sciencedirect.com
    The control of oligodendrocyte bioenergetics by interferon-gamma (IFN-γ) and Src homology region 2 domain-containing phosphatase-1 (SHP-1)
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      Curator: @evieth

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