35 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
    1
    1. scibot 07 Nov 2024
      RRID:AB_2199749

      DOI: 10.3389/fonc.2024.1441935

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
    1
    1. scibot 26 Sep 2024
      RRID:AB_2199749

      DOI: 10.1016/j.isci.2024.110693

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
  5. www.sciencedirect.com www.sciencedirect.com
    DDI2 protease controls embryonic development and inflammation via TCF11/NRF1
    1
    1. scibot 25 Sep 2024
      AB_2199749

      DOI: 10.1016/j.isci.2024.110893

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    sciencedirect.com/science/article/pii/S2589004224021187
  6. Aug 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
    1
    1. scibot 23 Aug 2024
      AB_2199749

      DOI: 10.1016/j.molcel.2024.08.006

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    sciencedirect.com/science/article/pii/S1097276524006609
  8. Jun 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
    1
    1. scibot 09 Jun 2024
      RRID:AB_2199749

      DOI: 10.1038/s44320-024-00040-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148061/
  10. May 2024
  11. aacrjournals.org aacrjournals.org
    TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity
    2
    1. scibot 23 May 2024
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      DOI: 10.1158/2159-8290.CD-23-0700

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    2. scibot 23 May 2024
      RRID:AB_2199749

      DOI: 10.1158/2159-8290.CD-23-0700

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    aacrjournals.org/cancerdiscovery/article/14/5/752/745044/TREX1-Inactivation-Unleashes-Cancer-Cell-STING
  12. www.sciencedirect.com www.sciencedirect.com
    Development of nitroalkene-based inhibitors to target STING-dependent inflammation
    1
    1. scibot 23 May 2024
      RRID:AB_2199749

      DOI: 10.1016/j.redox.2024.103202

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    sciencedirect.com/science/article/pii/S2213231724001800
  13. Apr 2024
  14. www.sciencedirect.com www.sciencedirect.com
    ISGylation by HERCs facilitates STING activation
    1
    1. scibot 23 Apr 2024
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2024.114135

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    sciencedirect.com/science/article/pii/S2211124724004637
  15. Nov 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
    1
    1. scibot 30 Nov 2023
      RRID:AB_2199749

      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  17. Sep 2023
  18. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
    1
    1. scibot 30 Sep 2023
      RRID:AB_2199749

      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
  19. www.sciencedirect.com www.sciencedirect.com
    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
    2
    1. scibot 16 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113108

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    2. scibot 16 Sep 2023
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2023.113108

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    sciencedirect.com/science/article/pii/S2211124723011191
  20. Mar 2023
  21. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
    1
    1. scibot 28 Mar 2023
      RRID:AB_225566

      DOI: 10.1016/j.celrep.2023.112303

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    europepmc.org/article/med/36952341
  22. europepmc.org europepmc.org
    UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS
    1
    1. scibot 23 Mar 2023
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2023.112272

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    europepmc.org/article/med/36943869
  23. Feb 2023
  24. www.cell.com www.cell.com
    Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma
    1
    1. scibot 16 Feb 2023
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2023.112127

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    cell.com/cell-reports/fulltext/S2211-1247(23)00138-9
  25. Jan 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response
    1
    1. scibot 05 Jan 2023
      RRID:AB_2199749

      DOI: 10.1016/j.molcel.2022.12.007

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    sciencedirect.com/science/article/pii/S1097276522011649
  27. Sep 2022
  28. www.sciencedirect.com www.sciencedirect.com
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
    1
    1. scibot 24 Sep 2022
      RRID:AB_2199749

      DOI: 10.1016/j.ccell.2022.08.015

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    sciencedirect.com/science/article/pii/S1535610822003798
  29. Jul 2022
  30. aacrjournals.org aacrjournals.org
    Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer
    1
    1. scibot 31 Jul 2022
      RRID:AB_2199749

      DOI: 10.1158/2767-9764.CRC-21-0139

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    aacrjournals.org/cancerrescommun/article/2/7/706/707154/Potent-Stimulation-of-the-Androgen-Receptor
  31. Jan 2022
  32. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
    1
    1. scibot 26 Jan 2022
      RRID:AB_2199749

      DOI: 10.1016/j.ccell.2021.12.009

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    sciencedirect.com/science/article/pii/S1535610821006620
  33. www.sciencedirect.com www.sciencedirect.com
    SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model
    1
    1. scibot 26 Jan 2022
      RRID:AB_2199749

      DOI: 10.1016/j.ebiom.2021.103808

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    sciencedirect.com/science/article/pii/S2352396421006022
  34. www.sciencedirect.com www.sciencedirect.com
    Native-PAGE analysis of protein aggregation upon viral infection in mouse macrophages
    1
    1. scibot 11 Jan 2022
      RRID:AB_2199749

      DOI: 10.1016/j.xpro.2021.101080

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    sciencedirect.com/science/article/pii/S2666166721007863
  35. Oct 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
    1
    1. scibot 23 Oct 2021
      RRID:AB_2199749

      DOI: 10.7554/eLife.72328

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    ncbi.nlm.nih.gov/pmc/articles/PMC8523161/
  37. Sep 2021
  38. www.sciencedirect.com www.sciencedirect.com
    The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation
    1
    1. scibot 22 Sep 2021
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2021.109731

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    sciencedirect.com/science/article/pii/S2211124721011803
  39. Aug 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
    1
    1. scibot 15 Aug 2021
      RRID:AB_2199749

      DOI: 10.1016/j.cell.2021.07.026

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    sciencedirect.com/science/article/pii/S0092867421008850
  41. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 09 Aug 2021
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2018.10.057

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    sciencedirect.com/science/article/pii/S2211124718316462
  42. Apr 2021
  43. www.sciencedirect.com www.sciencedirect.com
    TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
    1
    1. scibot 29 Apr 2021
      RRID:AB_2199749

      DOI: 10.1016/j.cmet.2020.10.010

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    sciencedirect.com/science/article/pii/S155041312030543X
  44. Jan 2021
  45. www.sciencedirect.com www.sciencedirect.com
    A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
    1
    1. scibot 08 Jan 2021
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2020.108586

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    sciencedirect.com/science/article/pii/S2211124720315758
  46. Dec 2020
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
    1
    1. scibot 17 Dec 2020
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2019.03.098

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    ncbi.nlm.nih.gov/pmc/articles/PMC7733315/
  48. Sep 2020
  49. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
    1
    1. scibot 16 Sep 2020
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2020.03.056

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    sciencedirect.com/science/article/pii/S2211124720303703
  50. rupress.org rupress.org
    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
    1
    1. scibot 16 Sep 2020
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      DOI: 10.1083/jcb.201912144

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    rupress.org/jcb/article/219/9/e201912144/151863/Critical-role-of-mitochondrial-ubiquitination-and
  51. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling
    1
    1. scibot 03 Sep 2020
      TBK1

      DOI: 10.1111/jcmm.15774

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    pubmed.ncbi.nlm.nih.gov/32858764/
  52. Jan 2020
  53. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2199749

      DOI: 10.1016/j.celrep.2019.03.098

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    sciencedirect.com/science/article/pii/S2211124719304371
  54. Nov 2018
  55. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0092867418309693
  56. Nov 2017
  57. www.sciencedirect.com www.sciencedirect.com
    Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517306536