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Feb 2026
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Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks

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Cooperative role of CD81 with GPR56 and collagen III in cortical formation

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sciencedirect.com/science/article/pii/S0168010226000222
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ttc21b is required for proper forebrain neural progenitor proliferation

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pmc.ncbi.nlm.nih.gov/articles/PMC12919951/
54.241.53.176 54.241.53.176

1-s2.0-S258900422600372X-main (1)-html.html

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54.241.53.176/59ddc9c67b664e5d95667967b600b72ca6e28235/1-s2.0-S258900422600372X-main (1)-html.html
Jan 2026
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Preferential vulnerability of cortical GABAergic interneurons to Nalcn deficiency

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  DOI: 10.64898/2026.01.21.700772
  
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biorxiv.org/content/10.64898/2026.01.21.700772v1
Dec 2025
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Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons

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sciencedirect.com:5037/science/article/pii/S2211124725015189
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MeCP2 regulates telencephalic development in human cerebral organoids

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Human PSC-derived organoids model sympathetic ganglion development and its functional crosstalk with the heart

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sciencedirect.com:5037/science/article/pii/S1934590925004102
Nov 2025
54.241.53.176 54.241.53.176

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54.241.53.176/7cc5e5effac0cd4b8778082ce64567b90bcc3f23/1-s2.0-S258900422502509X-main-html.html
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A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders

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sciencedirect.com/science/article/pii/S1934590925003741
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Generation of human nucleus basalis organoids with functional nbM-cortical cholinergic projections in transplanted assembloids

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sciencedirect.com/science/article/pii/S1934590925003728
Sep 2025
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Prenatal alcohol exposure perturbs the development of radial glial cells in the fetal olfactory bulb

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1. scibot 16 Sep 2025
  
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  DOI: 10.1111/acer.70161
  
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onlinelibrary.wiley.com/doi/10.1111/acer.70161
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Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis

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  DOI: 10.1016/j.celrep.2025.116276
  
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Cortical versus hippocampal network dysfunction in a human brain assembloid model of epilepsy and intellectual disability

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sciencedirect.com/science/article/pii/S221112472500988X
Aug 2025
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A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro

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  DOI: 10.1016/j.devcel.2025.08.001
  
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sciencedirect.com/science/article/pii/S1534580725005015
Jul 2025
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G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation

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  DOI: 10.1016/j.neuron.2025.06.020
  
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cell.com/neuron/fulltext/S0896-6273(25)00478-7
Jun 2025
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CacyBP/SIP Protein Regulates the Length and Branching of Neuronal Processes During Cortical Development

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  DOI: 10.1111/jnc.70115
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70115
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Molecular signatures of regional vulnerability to tauopathy in excitatory cortical neurons

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1. scibot 11 Jun 2025
  
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link.springer.com/article/10.1007/s00401-025-02879-2
May 2025
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1-s2.0-S2589004225009666-main-html.html

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52.53.155.43/24023f6b29126c53a5d7d52511b35095b078baff/1-s2.0-S2589004225009666-main-html.html
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Impact of ATF6 deletion on the embryonic brain development

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Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines

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Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B

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sciencedirect.com/science/article/pii/S1074761325001918
Apr 2025
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Identification of the core regulatory program driving NEUROD1-induced neuronal reprogramming

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Mar 2025
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Cadherin 4 assembles a family of color-preferring retinal circuits that respond to light offset

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sciencedirect.com/science/article/pii/S0960982225001423
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IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

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  DOI: 10.1002/advs.202501593
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202501593
Dec 2024
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The nucleoporin Nup153 is the anchor for Kif1a during basal nuclear migration in brain progenitor cells

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Oct 2024
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Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

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nature.com/articles/s41380-024-02761-9
Aug 2024
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Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity

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Jul 2024
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Impaired phase separation and nucleolar functions in hiPSC models of SNORD118-related ribosomopathies

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Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

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DCX knockout ferret reveals a neurogenic mechanism in cortical development

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Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins

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  DOI: 10.4103/NRR.NRR-D-23-00928
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11246146/
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A spatial–temporal map of glutamatergic neurogenesis in the murine embryonic cerebellar nuclei uncovers a high degree of cellular heterogeneity

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  DOI: 10.1111/joa.14107
  
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onlinelibrary.wiley.com/doi/10.1111/joa.14107
Jun 2024
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Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2

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  DOI: 10.1523/ENEURO.0106-24.2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11185043/
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Thalamic activity-dependent specification of sensory input neurons in the developing chick entopallium

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Cadherin 4 assembles a family of color-selective retinal circuits that respond to light offset

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Effective cryopreservation of human brain tissue and neural organoids

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ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum

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Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size

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Astrocyte-secreted neurocan controls inhibitory synapse formation and function

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Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a stem cell model of neurodevelopmental disorder

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Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders

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Quantifying differentiation of progenitor populations using cerebral organoid models for neurodevelopmental disorders

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Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models

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Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression

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Modeling the precise interaction of glioblastoma with human brain region-specific organoids

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3D bioprinting of human neural tissues with functional connectivity

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Fetal development of the human amygdala

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Origin and development of the claustrum in rhesus macaque

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Human fetal brain self-organizes into long-term expanding organoids

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Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons

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ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations

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Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb

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Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells

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Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons

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A novel architecture of PT neuron-based corticothalamic connectivity in the auditory system

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PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model

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Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice

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Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure

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Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

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SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex

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Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika Virus microcephaly

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Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic Neurons

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Morphological Diversity of Calretinin Interneurons Generated From Adult Mouse Olfactory Bulb Core Neural Stem Cells

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  DOI: 10.3389/fcell.2022.932297
  
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Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development

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Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex

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Heterozygous Dab1 null mutation disrupts neocortical and hippocampal development

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Origin and Development of the Claustrum in Rhesus Macaque

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Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations

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Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development

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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model

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Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain

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Structural and functional integration of human forebrain organoids with the injured adult rat visual system

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MicroRNA-218 regulates neuronal radial migration and morphogenesis by targeting Satb2 in developing neocortex

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Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway

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Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

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Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition

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Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization

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Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis

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A reference human induced pluripotent stem cell line for large-scale collaborative studies

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Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms

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Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development

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m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs

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A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes

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Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway

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The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse

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Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex

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Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment

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The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling

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Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model

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Mitigating Effect of Estrogen in Alzheimer’s Disease-Mimicking Cerebral Organoid

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Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain

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Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model

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AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins.

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Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

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Expression of Maf family proteins in glutamatergic neurons of the mouse olfactory bulb

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Oct 2021
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Characterization and manipulation of Corticothalamic neurons in associative cortices using Syt6-Cre transgenic mice

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Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1

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Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy

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A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation

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FLRT2 and FLRT3 cooperate in maintaining the tangential migratory streams of cortical interneurons during development

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  DOI: 10.1523/JNEUROSCI.0380-20.2021
  
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Sep 2021
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Integration of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons into Rat Brain Circuits

1
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  DOI: 10.21769/BioProtoc.3746
  
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Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding

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CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity

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Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons

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A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

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Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids

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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

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FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections

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The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number

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hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids

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Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

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TBR1 regulates autism risk genes in the developing neocortex

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Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis

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Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons

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DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction

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Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function

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The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis

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Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3

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Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion

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Cascade diversification directs generation of neuronal diversity in the hypothalamus

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Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis

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Impaired Cortical Cytoarchitecture and Reduced Excitability of Deep-Layer Neurons in the Offspring of Diabetic Rats

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Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

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Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse

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Protocol for generating human induced neural progenitor cells from immobilized adult peripheral blood

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Olig3 regulates early cerebellar development

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Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality

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Androgen Receptor signaling promotes the neural progenitor cell pool in the developing cortex

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LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

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A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development

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Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network

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Insights into olfactory ensheathing cell development from a laser‐microdissection and transcriptome‐profiling approach

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Tead transcription factors differentially regulate cortical development

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Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation

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Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons

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FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits

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Retinoic acid is required for oligodendrocyte precursor cell production and differentiation in the postnatal mouse corpus callosum

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In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons

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Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

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Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways

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Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

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Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates

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Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly

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Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons

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RhoA Controls Axon Extension Independent of Specification in the Developing Brain

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Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain both Excitatory and Inhibitory Synaptic Activities

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SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

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Regional differences in mitral cell development in mouse olfactory bulb

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Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis

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The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis

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Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells

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Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin

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Inducing Different Neuronal Subtypes from Astrocytes in the Injured Mouse Cerebral Cortex

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The PROK2/PROKR2 Signaling Pathway is Required for the Migration of Most Olfactory Bulb Interneurons

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Expression of ventral telencephalon transcription factors ASCL1 and DLX2 in the early fetal human cerebral cortex

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  DOI: 10.1016/j.neuron.2019.01.007
  
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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.neuron.2019.01.022
  
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Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

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1. scibot 12 Jan 2020
  
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  DOI: 10.7554/eLife.41241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6303107/
Nov 2018
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Human Huntington’s Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation

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1. scibot 05 Nov 2018
  
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Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory

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1. scibot 05 Nov 2018
  
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E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors’ activity in an E-box-dependent manner

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1. scibot 05 Nov 2018
  
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Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex

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Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness

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Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

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hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate

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Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination

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Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation

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The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position

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Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons

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Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

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Generation and Characterization of Functional Human Hypothalamic Neurons

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Transplantation of feeder‐free human induced pluripotent stem cell–derived cortical neuron progenitors in adult male Wistar rats with focal brain ischemia

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Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation

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1. scibot 08 Nov 2017
  
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Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment

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DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis

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