199 Matching Annotations
  1. Aug 2025
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    A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro
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    sciencedirect.com/science/article/pii/S1534580725005015
  3. Jul 2025
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    G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation
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    cell.com/neuron/fulltext/S0896-6273(25)00478-7
  5. Jun 2025
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    CacyBP/SIP Protein Regulates the Length and Branching of Neuronal Processes During Cortical Development
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70115
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    Molecular signatures of regional vulnerability to tauopathy in excitatory cortical neurons
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    link.springer.com/article/10.1007/s00401-025-02879-2
  8. May 2025
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    1-s2.0-S2589004225009666-main-html.html
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    Impact of ATF6 deletion on the embryonic brain development
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    sciencedirect.com/science/article/pii/S2589004225008302
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    Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines
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    sciencedirect.com/science/article/pii/S1934590925001419
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    Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B
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    sciencedirect.com/science/article/pii/S1074761325001918
  13. Apr 2025
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    Identification of the core regulatory program driving NEUROD1-induced neuronal reprogramming
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  15. Mar 2025
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    Cadherin 4 assembles a family of color-preferring retinal circuits that respond to light offset
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    sciencedirect.com/science/article/pii/S0960982225001423
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    IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202501593
  18. Dec 2024
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    The nucleoporin Nup153 is the anchor for Kif1a during basal nuclear migration in brain progenitor cells
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    sciencedirect.com/science/article/pii/S2211124724013597
  20. Oct 2024
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    Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
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    nature.com/articles/s41380-024-02761-9
  22. Aug 2024
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    Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity
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  25. Jul 2024
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    Impaired phase separation and nucleolar functions in hiPSC models of SNORD118-related ribosomopathies
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    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
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    sciencedirect.com/science/article/pii/S2666379124003616
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    DCX knockout ferret reveals a neurogenic mechanism in cortical development
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    Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins
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    ncbi.nlm.nih.gov/pmc/articles/PMC11246146/
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    A spatial–temporal map of glutamatergic neurogenesis in the murine embryonic cerebellar nuclei uncovers a high degree of cellular heterogeneity
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    onlinelibrary.wiley.com/doi/10.1111/joa.14107
  31. Jun 2024
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    Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11185043/
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    Thalamic activity-dependent specification of sensory input neurons in the developing chick entopallium
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    onlinelibrary.wiley.com/doi/10.1002/cne.25627
  34. May 2024
  35. www.biorxiv.org www.biorxiv.org
    Cadherin 4 assembles a family of color-selective retinal circuits that respond to light offset
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    Effective cryopreservation of human brain tissue and neural organoids
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    ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
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    Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
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  39. Apr 2024
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    Astrocyte-secreted neurocan controls inhibitory synapse formation and function
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  41. Mar 2024
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    Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a stem cell model of neurodevelopmental disorder
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    Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders
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    Quantifying differentiation of progenitor populations using cerebral organoid models for neurodevelopmental disorders
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    Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models
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    Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
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  47. Feb 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling the precise interaction of glioblastoma with human brain region-specific organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10882168/
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    3D bioprinting of human neural tissues with functional connectivity
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  50. Jan 2024
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fetal development of the human amygdala
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    onlinelibrary.wiley.com/doi/10.1002/cne.25580
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Origin and development of the claustrum in rhesus macaque
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    ncbi.nlm.nih.gov/pmc/articles/PMC10334778/
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    Human fetal brain self-organizes into long-term expanding organoids
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  54. Dec 2023
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    Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons
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    ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations
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    Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb
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  58. Nov 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10629821/
  60. Oct 2023
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    Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons
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    sciencedirect.com/science/article/pii/S2211124723013475
  62. www.biorxiv.org www.biorxiv.org
    A novel architecture of PT neuron-based corticothalamic connectivity in the auditory system
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    biorxiv.org/content/10.1101/2023.08.08.552413v2
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10521973/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11296311/
  65. Aug 2023
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    Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure
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  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC10542749/
  68. Jun 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285642/
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    Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika Virus microcephaly
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  71. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic Neurons
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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.786
  72. May 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Morphological Diversity of Calretinin Interneurons Generated From Adult Mouse Olfactory Bulb Core Neural Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9277347/
  74. Apr 2023
  75. www.biorxiv.org www.biorxiv.org
    Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development
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    biorxiv.org/content/10.1101/2023.04.05.535746v1
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    Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
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    Heterozygous Dab1 null mutation disrupts neocortical and hippocampal development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10089055/
  78. www.biorxiv.org www.biorxiv.org
    Origin and Development of the Claustrum in Rhesus Macaque
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    biorxiv.org/content/10.1101/2023.02.06.527286v1
  79. Mar 2023
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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    Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development
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  82. Feb 2023
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    Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model
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    Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain
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    Structural and functional integration of human forebrain organoids with the injured adult rat visual system
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  86. Jan 2023
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    MicroRNA-218 regulates neuronal radial migration and morphogenesis by targeting Satb2 in developing neocortex
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    sciencedirect.com/science/article/pii/S0006291X23000840
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    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway
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    Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels
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    Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition
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    Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization
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    link.springer.com/article/10.1007/s00429-022-02606-7
  92. Dec 2022
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9753470/
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    A reference human induced pluripotent stem cell line for large-scale collaborative studies
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  95. Oct 2022
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9523398/
  97. Sep 2022
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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    sciencedirect.com/science/article/pii/S2211124722011780
  99. Aug 2022
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    m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs
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    A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9346488/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse
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    ncbi.nlm.nih.gov/pmc/articles/PMC9347289/
  104. Jul 2022
  105. link.springer.com link.springer.com
    Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
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    link.springer.com/article/10.1007/s12035-022-02936-x
  106. May 2022
  107. www.sciencedirect.com www.sciencedirect.com
    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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    The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
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    Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model
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  110. Apr 2022
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitigating Effect of Estrogen in Alzheimer’s Disease-Mimicking Cerebral Organoid
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    ncbi.nlm.nih.gov/pmc/articles/PMC8990972/
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC8969024/
  113. Jan 2022
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    Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model
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    sciencedirect.com/science/article/pii/S258900422101628X
  115. Dec 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins.
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    ncbi.nlm.nih.gov/pmc/articles/PMC8668991/
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A
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    ncbi.nlm.nih.gov/pmc/articles/PMC8610419/
  118. Nov 2021
  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression of Maf family proteins in glutamatergic neurons of the mouse olfactory bulb
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    onlinelibrary.wiley.com/doi/10.1002/dneu.22859
  120. Oct 2021
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization and manipulation of Corticothalamic neurons in associative cortices using Syt6-Cre transgenic mice
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    onlinelibrary.wiley.com/doi/10.1002/cne.25256
  122. www.jneurosci.org www.jneurosci.org
    Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1
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  224. Nov 2017
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    Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
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    Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment
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    DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis
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    Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells
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    Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules
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    Assembly of Excitatory Synapses in the Absence of Glutamatergic Neurotransmission
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    Tridimensional Visualization and Analysis of Early Human Development
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    Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
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    Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease
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