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Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116993
  
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sciencedirect.com/science/article/pii/S2211124726000719
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

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1. scibot 29 Nov 2025
  
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sciencedirect.com:5037/science/article/pii/S2211124725013956
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Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.bcp.2025.117562
  
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sciencedirect.com:5037/science/article/pii/S0006295225008275
Jun 2025
www.tandfonline.com www.tandfonline.com

Screening of medicine-food homology drugs for anti-colorectal cancer based on network pharmacology, molecular docking and in vitro experiments

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1. scibot 28 Jun 2025
  
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  DOI: 10.1080/19476337.2025.2460690
  
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2. scibot 18 Jun 2025
  
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  DOI: 10.1080/19476337.2025.2460690
  
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tandfonline.com/doi/full/10.1080/19476337.2025.2460690
Sep 2024
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A TBK1-independent primordial function of STING in lysosomal biogenesis

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.026
  
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sciencedirect.com/science/article/pii/S1097276524007032
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle

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1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.devcel.2020.07.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
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Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

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1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110144
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
Jun 2024
www.cell.com www.cell.com

Oncogenic HPV-induced high expression of ESM1 predicts poor prognosis and regulates aerobic glycolysis in cervical cancer

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1. scibot 30 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110112
  
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cell.com/iscience/abstract/S2589-0042(24)01337-3
Apr 2024
52.53.155.43 52.53.155.43

The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis

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1. scibot 11 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109510
  
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52.53.155.43/e4a741173d4beb6859350a39a8e5091b3ba2fb02/1-s2.0-S2589004224007314-main-html.html
Mar 2024
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A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice

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1. scibot 13 Mar 2024
  
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  DOI: 10.1016/j.molcel.2024.02.019
  
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sciencedirect.com/science/article/pii/S1097276524001382
Dec 2023
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TCF12 regulates the TGF-β/Smad2/3 signaling pathway to accelerate the progression of osteoarthritis by targeting CXCR4

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.jot.2023.11.006
  
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sciencedirect.com/science/article/pii/S2214031X23000967
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A protocol to investigate the effects of lncRNAs on in vivo protein-protein interactions using proximity ligation assay

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1. scibot 10 Dec 2023
  
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  DOI: 10.1016/j.xpro.2023.102757
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10701416/
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Acid-base homeostasis orchestrated by NHE1 defines the pancreatic stellate cell phenotype in pancreatic cancer

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1. scibot 03 Nov 2023
  
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  DOI: 10.1172/jci.insight.170928
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10619433/
Jul 2023
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A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112833
  
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sciencedirect.com/science/article/pii/S2211124723008446
Apr 2023
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CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue

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1. scibot 22 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112424
  
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sciencedirect.com/science/article/pii/S2211124723004357
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Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission

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1. scibot 04 Apr 2023
  
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  DOI: 10.1016/j.biopha.2023.114616
  
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sciencedirect.com/science/article/pii/S0753332223004043
Feb 2023
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N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.chembiol.2023.01.006
  
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sciencedirect.com/science/article/pii/S2451945623000296
Jan 2023
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PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.isci.2022.105909
  
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  DOI: 10.1016/j.isci.2022.105909
  
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sciencedirect.com/science/article/pii/S2589004222021824
Mar 2022
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SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.devcel.2022.01.011
  
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sciencedirect.com/science/article/pii/S1534580722000363
Dec 2021
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Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity

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1. scibot 21 Dec 2021
  
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sciencedirect.com/science/article/pii/S1534580721009448
Nov 2021
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Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction

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1. scibot 25 Nov 2021
  
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  DOI: 10.1016/j.ebiom.2021.103713
  
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sciencedirect.com/science/article/pii/S2352396421005077
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The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8593568/
Aug 2021
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Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.ebiom.2018.11.056
  
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sciencedirect.com/science/article/pii/S2352396418305607
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle

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1. scibot 05 May 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
Sep 2020
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Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion

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  DOI: 10.1016/j.celrep.2020.107879
  
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sciencedirect.com/science/article/pii/S2211124720308603
Jan 2020
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GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.yexcr.2019.111806
  
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sciencedirect.com/science/article/pii/S0014482719306949
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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.028
  
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sciencedirect.com/science/article/pii/S2211124719303444