115 Matching Annotations
  1. Last 7 days
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    Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model
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    1. scibot 15 May 2024
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      DOI: 10.1007/s11033-024-09548-9

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  3. May 2024
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    Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation
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    1. scibot 03 May 2024
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    sciencedirect.com/science/article/pii/S2211124724004935
  5. Apr 2024
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    Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004972
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    The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
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    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003619
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    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983109/
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.cell.2024.03.005

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    sciencedirect.com/science/article/pii/S0092867424002538
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    Molecular determinants and signaling effects of PKA RIα phase separation
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    1. scibot 28 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001849
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    1. scibot 19 Mar 2024
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    A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development
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    1. scibot 14 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002456
  14. Feb 2024
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    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
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    1. scibot 16 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001207
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    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
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    1. scibot 02 Feb 2024
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    sciencedirect.com/science/article/pii/S1097276524000078
  17. Jan 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 26 Jan 2024
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      DOI: 10.1101/2023.05.04.539399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
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    HSP70 binds to specific non-coding RNA and regulates human RNA polymerase III
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    1. scibot 25 Jan 2024
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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.isci.2023.108650

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 11 Jan 2024
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    sciencedirect.com/science/article/pii/S1097276523010225
  22. Dec 2023
  23. dx.doi.org dx.doi.org
    Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
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    1. scibot 30 Dec 2023
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      DOI: 10.1158/0008-5472.CAN-22-2108

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    dx.doi.org/10.1158/0008-5472.CAN-22-2108
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    Dapagliflozin protects against chronic heart failure in mice by inhibiting macrophage-mediated inflammation, independent of SGLT2
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    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.xcrm.2023.101334

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    sciencedirect.com/science/article/pii/S2666379123005517
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    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
    1
    1. scibot 14 Dec 2023
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      DOI: 10.1016/j.molmet.2023.101851

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    sciencedirect.com/science/article/pii/S2212877823001850
  26. Nov 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.chembiol.2023.10.003

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    sciencedirect.com/science/article/abs/pii/S2451945623003392
  28. Oct 2023
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of SELENOF translation by eIF4a3: Possible role in prostate cancer progression
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1002/mc.23616

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    onlinelibrary.wiley.com/doi/10.1002/mc.23616
  30. www.sciencedirect.com www.sciencedirect.com
    LncRNA CFRL aggravates cardiac fibrosis by modulating both miR-3113-5p/CTGF and miR-3473d/FN1 axis
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.isci.2023.108039

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    sciencedirect.com/science/article/pii/S2589004223021168
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    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101214

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    sciencedirect.com/science/article/pii/S2666379123003816
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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      DOI: 10.1016/j.celrep.2023.113180

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    sciencedirect.com/science/article/pii/S2211124723011920
  33. Sep 2023
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Guanosine increases global SUMO1-ylation in the hippocampus of young and aged mice and improves the short-term memory of young mice
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      DOI: 10.1111/jnc.15920

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15920
  35. Jul 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.immuni.2023.07.002

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    sciencedirect.com/science/article/pii/S107476132300314X
  37. Jun 2023
  38. dx.doi.org dx.doi.org
    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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    1. scibot 10 Jun 2023
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      DOI: 10.1158/1541-7786.MCR-22-0552

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    dx.doi.org/10.1158/1541-7786.MCR-22-0552
  39. May 2023
  40. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.ebiom.2022.104155

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    sciencedirect.com/science/article/pii/S235239642200336X
  41. Apr 2023
  42. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
    1
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      DOI: 10.1158/2326-6066.CIR-22-0056

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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
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    Optogenetic Activation of UCP1-Dependent Thermogenesis in Brown Adipocytes
    1
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      DOI: 10.1016/j.isci.2023.106560

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    sciencedirect.com/science/article/pii/S2589004223006375
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  45. Mar 2023
  46. www.nature.com www.nature.com
    IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis
    1
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      DOI: 10.1038/s41388-023-02671-0

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    nature.com/articles/s41388-023-02671-0
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    Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke
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      DOI: 10.1016/j.celrep.2023.112233

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    sciencedirect.com/science/article/pii/S2211124723002449
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schwann cells contribute to demyelinating diabetic neuropathy and nerve terminal structures in white adipose tissue
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      DOI: 10.1016/j.isci.2023.106189

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    ncbi.nlm.nih.gov/pmc/articles/PMC9989657/
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    Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity
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      DOI: 10.1016/j.cmet.2023.02.006

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    sciencedirect.com/science/article/pii/S1550413123000426
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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      DOI: 10.1016/j.celrep.2023.112188

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    sciencedirect.com/science/article/pii/S2211124723001997
  51. Feb 2023
  52. www.sciencedirect.com www.sciencedirect.com
    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
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      DOI: 10.1016/j.celrep.2023.112129

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    sciencedirect.com/science/article/pii/S2211124723001407
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling
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    1. scibot 23 Feb 2023
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      DOI: 10.2337/db22-0444

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    ncbi.nlm.nih.gov/pmc/articles/PMC9935493/
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    β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence
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      DOI: 10.1016/j.mito.2022.12.004

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    sciencedirect.com/science/article/pii/S1567724922001088
  55. Jan 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation couples insulin hypersecretion with β cell failure in diabetes
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    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
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  58. Dec 2022
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  61. Oct 2022
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  63. Sep 2022
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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
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      Rat anti-mouse β-tubulin antibody

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  65. Aug 2022
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  67. Jul 2022
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    Exosomal microRNAs miR-30d-5p and miR-126a-5p Are Associated with Heart Failure with Preserved Ejection Fraction in STZ-Induced Type 1 Diabetic Rats
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    A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
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  72. May 2022
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    A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair
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  74. Apr 2022
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    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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  76. Mar 2022
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  78. Feb 2022
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    DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding
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  81. Jan 2022
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    The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis
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  83. Dec 2021
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    Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses
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  85. Sep 2021
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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  88. Aug 2021
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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  95. Jul 2021
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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  99. May 2021
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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      rabbit anti-β-Tubulin

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    The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
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    Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
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  109. Feb 2021
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    Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers
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  114. Dec 2020
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  116. Sep 2020
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    SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
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    HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
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    Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons
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    Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
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  122. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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    Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity
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      β-tubulin

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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bmal1 integrates mitochondrial metabolism and macrophage activation
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  126. Jan 2020
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    DLK mediates the neuronal intrinsic immune response and regulates glial reaction and neuropathic pain
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  128. www.nrcresearchpress.com www.nrcresearchpress.com
    Involvement of Akt-dependent CREB signaling pathway in hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-induced early growth response protein-1 (Egr-1) expression in vascular smooth muscle cells - Canadian Journal of Physiology and Pharmacology
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  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury
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    Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
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    Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21
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    sciencedirect.com/science/article/pii/S2211124719310174
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    Nuclear AGO1 Regulates Gene Expression by Affecting Chromatin Architecture in Human Cells
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    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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      DOI: 10.1016/j.ccell.2019.10.002

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    Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
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    sciencedirect.com/science/article/pii/S2211124719314123
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    Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma
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    12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat
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  137. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase B mediates insulin‐like growth factor 1‐induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells
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      DOI: 10.1002/jcp.28353

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      RRID:AB_2210545

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    Mitochondria‐coupled glucose phosphorylation develops after birth to modulate H2O2 release and calcium handling in rat brain
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      DOI: 10.1111/jnc.14705

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    Lysosome Positioning Influences mTORC2 and AKT Signaling
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  143. Nov 2018
  144. www.sciencedirect.com www.sciencedirect.com
    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
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    Chemical hypoxia‐induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (NRF2)
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    Region-Specific Suppression of Hypothalamic Responses to Insulin To Adapt to Elevated Maternal Insulin Secretion During Pregnancy
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    Reestablishment of Energy Balance in a Male Mouse Model With POMC Neuron Deletion of BMPR1A
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  148. Nov 2017
  149. www.sciencedirect.com www.sciencedirect.com
    The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity
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    Inflammatory Stimuli Increase Progesterone Receptor-A Stability and Transrepressive Activity in Myometrial Cells
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  151. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STIM‐1 and ORAI‐1 channel mediate angiotensin‐II‐induced expression of Egr‐1 in vascular smooth muscle cells
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    onlinelibrary.wiley.com/wol1/doi/10.1002/jcp.25810/full
  152. elifesciences.org elifesciences.org
    Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors
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      β-tubulin

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