96 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Degradome analysis to identify direct protein substrates of small-molecule degraders
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    1. scibot 14 Nov 2024
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    sciencedirect.com/science/article/pii/S2451945624004422
  3. Sep 2024
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    RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery
    1
    1. scibot 25 Sep 2024
      RRID:AB_10707327

      DOI: 10.1016/j.celrep.2019.08.022

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    sciencedirect.com/science/article/pii/S2211124719310563
  5. Aug 2024
  6. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C
    1
    1. scibot 02 Aug 2024
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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0332-8
  7. Jul 2024
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    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
    1
    1. scibot 24 Jul 2024
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    sciencedirect.com/science/article/pii/S1074761324002796
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    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
    1
    1. scibot 24 Jul 2024
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    sciencedirect.com/science/article/pii/S1097276524004799
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2
    1
    1. scibot 18 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC7680438/
  11. Jun 2024
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    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S0092867424004938
  13. May 2024
  14. 52.53.155.43 52.53.155.43
    2024.02.25.581951v1.full-html.html
    1
    1. scibot 16 May 2024
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      DOI: 10.1038/nature12362

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    52.53.155.43/3cbbb6c4022cb0d94766603ef526c2fd13dcbc89/2024.02.25.581951v1.full-html.html
  15. Apr 2024
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    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
    1
    1. scibot 18 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004479
  17. Mar 2024
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    PABPC1 mediates degradation of C9orf72-FTLD/ALS GGGGCC repeat RNA
    1
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109303

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    sciencedirect.com/science/article/pii/S2589004224005248
  19. Feb 2024
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    Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production
    1
    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S1074761324000773
  21. Jan 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046306/
  23. Nov 2023
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    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.112659

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    sciencedirect.com/science/article/pii/S2211124723006708
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    Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113262

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    sciencedirect.com/science/article/pii/S2211124723012743
  26. May 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
  28. Apr 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
    1
    1. scibot 09 Apr 2023
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      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.isci.2023.106107

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    sciencedirect.com/science/article/pii/S2589004223001840
  32. Jan 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation
    1
    1. scibot 26 Jan 2023
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      DOI: 10.1016/j.jcmgh.2022.10.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC9868690/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pan-Cancer Analysis Reveals Recurrent BCAR4 Gene Fusions across Solid Tumors
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1158/1541-7786.MCR-21-0775

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    ncbi.nlm.nih.gov/pmc/articles/PMC9530645/
  35. Dec 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization
    1
    1. scibot 31 Dec 2022
      RRID:AB_2217020

      DOI: 10.1083/jcb.202204039

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    ncbi.nlm.nih.gov/pmc/articles/PMC9754704/
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    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111742

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    sciencedirect.com/science/article/pii/S2211124722016205
  38. Nov 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry
    1
    1. scibot 19 Nov 2022
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      DOI: 10.1016/j.isci.2022.105481

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    ncbi.nlm.nih.gov/pmc/articles/PMC9668739/
  40. Sep 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
    1
    1. scibot 11 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.012

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    sciencedirect.com/science/article/pii/S1535610822003762
  42. Apr 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.chembiol.2022.03.010

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    sciencedirect.com/science/article/pii/S2451945622001271
  44. Feb 2022
  45. www.sciencedirect.com www.sciencedirect.com
    TMEM106A inhibits enveloped virus release from cell surface
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.isci.2022.103843

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      DOI: 10.1016/j.isci.2022.103843

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    sciencedirect.com/science/article/pii/S2589004222001134
  46. Dec 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell mapping of DNA G-quadruplex structures in human cancer cells
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    1. scibot 11 Dec 2021
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      DOI: 10.1038/s41598-021-02943-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8654944/
  48. Nov 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
    1
    1. scibot 05 Nov 2021
      RRID:AB_2217020

      DOI: 10.7554/eLife.57462

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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  50. Oct 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
    1
    1. scibot 14 Oct 2021
      2368

      DOI: 10.1016/j.jbc.2021.101291

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    sciencedirect.com/science/article/pii/S0021925821010966
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    A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development
    1
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      DOI: 10.1016/j.cell.2021.09.021

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    sciencedirect.com/science/article/pii/S0092867421011041
  53. Sep 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Structural basis and regulation of the reductive stress response
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      DOI: 10.1016/j.cell.2021.09.002

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    sciencedirect.com/science/article/pii/S0092867421010497
  55. Aug 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
    1
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      DOI: 10.7554/eLife.64846

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    ncbi.nlm.nih.gov/pmc/articles/PMC8370767/
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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      DOI: 10.1016/j.neuron.2021.07.007

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    sciencedirect.com/science/article/pii/S0896627321005067
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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      DOI: 10.1016/j.celrep.2021.109512

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    sciencedirect.com/science/article/pii/S2211124721009426
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    Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection
    1
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      DOI: 10.1016/j.molcel.2018.11.017

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    sciencedirect.com/science/article/pii/S1097276518309870
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.celrep.2018.10.049

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    sciencedirect.com/science/article/pii/S2211124718316383
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    Essential role of Msx1 in regulating anterior-posterior patterning of the secondary palate in mice
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      2368

      DOI: 10.1016/j.jgg.2021.07.006

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    sciencedirect.com/science/article/pii/S1673852721002162
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    Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity
    1
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      RRID:AB_2217020

      DOI: 10.1016/j.cell.2017.06.042

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    sciencedirect.com/science/article/pii/S0092867417307614
  63. Jul 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association
    1
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      DOI: 10.1016/j.celrep.2018.10.049

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    ncbi.nlm.nih.gov/pmc/articles/PMC6261462/
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    Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
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  66. www.sciencedirect.com www.sciencedirect.com
    Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread
    1
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  67. www.sciencedirect.com www.sciencedirect.com
    Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells
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  68. Jun 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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  70. May 2021
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    Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms
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    LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2
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    Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation
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    NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
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      Rabbit monoclonal anti-DYKDDDK Tag

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    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
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    FGF Pyramus Has a Transmembrane Domain and Cell-Autonomous Function in Polarity
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  78. Apr 2021
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    Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
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  80. www.cell.com www.cell.com
    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
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    A Cellular Mechanism to Detect and Alleviate Reductive Stress
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    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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    Reducing acetylated tau is neuroprotective in brain injury
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  86. www.jneurosci.org www.jneurosci.org
    NOX1/NADPH oxidase promotes synaptic facilitation induced by repeated D2 receptor stimulation; involvement in behavioral repetition
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    SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
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  88. Mar 2021
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    Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling
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  90. Nov 2020
  91. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
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  92. Oct 2020
  93. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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  94. Sep 2020
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy
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    Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
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    A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK signalling regulates antioxidant responses in neurons
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  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition
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    DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells
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    Mitotic Implantation of the Transcription Factor Prospero via Phase Separation Drives Terminal Neuronal Differentiation
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    Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder
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    Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
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    A Structure-Informed Atlas of Human-Virus Interactions
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    Proximity RNA Labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules
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    SLC19A1 Is an Importer of the Immunotransmitter cGAMP
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    sciencedirect.com/science/article/pii/S0092867418316441
  113. www.sciencedirect.com www.sciencedirect.com
    Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production
    1
    1. scibot 12 Jan 2020
      RRID:AB_2217020

      DOI: 10.1016/j.immuni.2018.12.013

      Resource: (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

      Curator: @ethanbadger

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      RRID:AB_2217020 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761318305612
  114. Nov 2018
  115. www.sciencedirect.com www.sciencedirect.com
    Assembly and Translocation of a CRISPR-Cas Primed Acquisition Complex
    1
    1. scibot 05 Nov 2018
      RRID:AB_2217020

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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      RRID:AB_2217020 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418312510
  116. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_2217020

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    sciencedirect.com/science/article/pii/S2211124718314888
  117. www.sciencedirect.com www.sciencedirect.com
    Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions
    1
    1. scibot 05 Nov 2018
      RRID:AB_2217020

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    sciencedirect.com/science/article/pii/S1097276518306002
  118. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
    1
    1. scibot 05 Nov 2018
      AB_2217020

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    sciencedirect.com/science/article/pii/S0092867418309693
  119. www.sciencedirect.com www.sciencedirect.com
    Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia
    1
    1. scibot 05 Nov 2018
      RRID:AB_2217020

      Curator: @anp055

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    sciencedirect.com/science/article/pii/S1535610818302605
  120. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
    1
    1. scibot 05 Nov 2018
      2368

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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      RRID:AB_2217020 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867418300412
  121. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
    1
    1. scibot 05 Nov 2018
      RRID:AB_2217020

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    sciencedirect.com/science/article/pii/S1550413117305703
  122. www.sciencedirect.com www.sciencedirect.com
    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
    1
    1. scibot 05 Nov 2018
      RRID:AB_2217020

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    sciencedirect.com/science/article/pii/S1097276518302326
  123. www.sciencedirect.com www.sciencedirect.com
    Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2217020

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    sciencedirect.com/science/article/pii/S1535610818300655
  124. Nov 2017
  125. www.sciencedirect.com www.sciencedirect.com
    Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
    1
    1. scibot 08 Nov 2017
      2368S

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    sciencedirect.com/science/article/pii/S1097276517301284
  126. www.sciencedirect.com www.sciencedirect.com
    RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health
    1
    1. scibot 08 Nov 2017
      FLAGCell Signaling2368

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    sciencedirect.com/science/article/pii/S1097276517302770
  127. www.sciencedirect.com www.sciencedirect.com
    Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals
    1
    1. scibot 08 Nov 2017
      Rabbit polyclonal anti-DYKDDDK Tag Antibody (FLAG)

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    sciencedirect.com/science/article/pii/S1097276517304082
  128. www.sciencedirect.com www.sciencedirect.com
    Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development
    1
    1. scibot 08 Nov 2017
      AB_2217020

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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      RRID:AB_2217020 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717303957
  129. www.jneurosci.org www.jneurosci.org
    Regulation of Alcohol Extinction and Cue-Induced Reinstatement by Specific Projections among Medial Prefrontal Cortex, Nucleus Accumbens, and Basolateral Amygdala
    1
    1. scibot 08 Nov 2017
      AB_2217020

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

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    jneurosci.org/content/37/17/4462
  130. elifesciences.org elifesciences.org
    Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator
    1
    1. scibot 08 Nov 2017
      AB_2217020

      Curator: @kaitlinsung

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

      SciCrunch record: RRID:AB_2217020

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    elifesciences.org/articles/23063
  131. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C
    1
    1. scibot 08 Nov 2017
      AB_2217020

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 2368, RRID:AB_2217020)

      SciCrunch record: RRID:AB_2217020

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      RRID:AB_2217020 RRIDCUR:Validated
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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0332-8