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Activation of TREM2 via single-domain antibodies improves synaptic and cognitive function in 5×FAD mice

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sciencedirect.com/science/article/pii/S2211124726011423
Sep 2026
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B cell responses to CD40 stimulation ignite anti-tumor immunity by activating CD8+ T cell cytotoxicity

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  DOI: 10.1016/j.celrep.2026.117957
  
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sciencedirect.com/science/article/pii/S2211124726010351
Aug 2026
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B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

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1. scibot 04 Aug 2026
  
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  DOI: 10.1002/advs.76869
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76869
May 2026
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Ablation of the adhesion G protein-coupled receptor ADGRL1 activates anti-tumor immune response via cDC1-T cell hub formation

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sciencedirect.com/science/article/pii/S2211124726004870
Apr 2026
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1-s2.0-S2589004226011764-main-html.html

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54.241.53.176/8488015b440db33861248d6c24369f9587bf2f0a/1-s2.0-S2589004226011764-main-html.html
Mar 2026
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Collagen-bearing exosomes from breast cancer-associated fibroblasts promote T cell dysfunction

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  DOI: 10.1158/2767-9764.CRC-25-0259
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13012019/
Jan 2026
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Cholesterol-DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

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  DOI: 10.1002/admi.202500806
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/admi.202500806
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DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling

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sciencedirect.com/science/article/pii/S2211124725015682
Sep 2025
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A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation

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sciencedirect.com/science/article/pii/S2451945625002594
Aug 2025
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Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

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  DOI: 10.1016/j.celrep.2025.116177
  
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Succinate preserves CD8+ T cell fitness to augment antitumor immunity

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.017
  
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sciencedirect.com/science/article/pii/S1074761325003267
Aug 2024
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

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1. scibot 23 Aug 2024
  
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  DOI: 10.7554/eLife.76940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
May 2024
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Distinct roles of TREM2 in central nervous system cancers and peripheral cancers

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1. scibot 24 May 2024
  
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Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas

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sciencedirect.com/science/article/pii/S1535610824001314
Apr 2024
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ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion

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1. scibot 16 Apr 2024
  
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  DOI: 10.1016/j.cell.2024.03.019
  
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sciencedirect.com/science/article/pii/S0092867424003106
Mar 2024
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Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias

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1. scibot 16 Mar 2024
  
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  DOI: 10.1038/s44319-024-00077-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

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1. scibot 13 Mar 2024
  
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  DOI: 10.1016/j.immuni.2024.02.014
  
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  DOI: 10.1016/j.immuni.2024.02.014
  
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sciencedirect.com/science/article/pii/S1074761324000906
Feb 2024
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Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias

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1. scibot 15 Feb 2024
  
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  DOI: 10.1038/s44319-024-00077-x
  
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embopress.org/doi/10.1038/s44319-024-00077-x
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Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas

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  DOI: 10.1158/2159-8290.CD-22-1401
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
Dec 2023
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SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells

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sciencedirect.com/science/article/pii/S2211124723015188
Sep 2023
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Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI

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sciencedirect.com/science/article/pii/S2589004223018266
Jul 2023
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Heterogeneity of Signaling Complex Nanostructure in T Cells Activated Via the T Cell Antigen Receptor

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  DOI: 10.1093/micmic/ozad072
  
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dx.doi.org/10.1093/micmic/ozad072
Apr 2023
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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

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sciencedirect.com/science/article/pii/S2211124723004473
Feb 2023
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IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment

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sciencedirect.com/science/article/pii/S153561082300003X
Jan 2023
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Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

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  DOI: 10.1016/j.immuni.2022.11.013
  
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Oct 2022
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TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

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  DOI: 10.1016/j.cell.2022.09.033
  
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sciencedirect.com/science/article/pii/S0092867422012521
Sep 2022
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cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells

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  DOI: 10.1016/j.celrep.2022.111373
  
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sciencedirect.com/science/article/pii/S2211124722012050
Mar 2022
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Coordinated changes in glycosylation regulate the germinal center through CD22

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  DOI: 10.1016/j.celrep.2022.110512
  
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3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells

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  DOI: 10.1016/j.stem.2022.02.009
  
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sciencedirect.com/science/article/pii/S1934590922000601
Nov 2021
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CXCL12 May Drive Inflammatory Potential in the Ovine Corpus Luteum During Implantation

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  DOI: 10.1007/s43032-021-00791-0
  
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link.springer.com/article/10.1007/s43032-021-00791-0/tables/2
Oct 2021
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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

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  DOI: 10.1016/j.celrep.2021.109804
  
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sciencedirect.com/science/article/pii/S221112472101264X
Aug 2021
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Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

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1. scibot 17 Aug 2021
  
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  DOI: 10.1016/j.isci.2021.102871
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8346660/
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Untitled document

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1. scibot 10 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.10.008
  
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sciencedirect.com/science/article/pii/S1074761318304497
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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

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1. scibot 07 Aug 2021
  
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  DOI: 10.7554/eLife.69975
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
Jun 2021
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Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch

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1. scibot 23 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109280
  
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sciencedirect.com/science/article/pii/S2211124721006471
May 2021
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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

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1. scibot 07 May 2021
  
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  RRID:AB_2218658
  
  DOI: 10.1016/j.immuni.2020.09.006
  
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sciencedirect.com/science/article/pii/S1074761320304003
Apr 2021
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Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

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1. scibot 20 Apr 2021
  
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  RRID:AB_2218658
  
  DOI: 10.1016/j.molcel.2021.03.043
  
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sciencedirect.com/science/article/pii/S1097276521002641
Feb 2021
www.cell.com www.cell.com

Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

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1. scibot 24 Feb 2021
  
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  RRID:AB_2218658
  
  DOI: 10.1016/j.celrep.2020.01.008
  
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cell.com/cell-reports/abstract/S2211-1247(20)30017-6
Dec 2020
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Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation

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1. scibot 30 Dec 2020
  
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  RRID:AB_2218658
  
  DOI: 10.1016/j.celrep.2020.108523
  
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sciencedirect.com/science/article/pii/S2211124720315126
Sep 2020
www.cell.com www.cell.com

Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2218658
  
  DOI: 10.1016/j.celrep.2020.01.008
  
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cell.com/cell-reports/abstract/S2211-1247(20)30017-6
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SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

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1. scibot 17 Sep 2020
  
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  RRID:AB_2218658
  
  DOI: 10.7554/eLife.56656
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7250567/
Jan 2020
elifesciences.org elifesciences.org

Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_2218658
  
  DOI: 10.7554/eLife.46043
  
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EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection

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1. scibot 13 Jan 2020
  
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  RRID:AB_2218658
  
  DOI: 10.1016/j.celrep.2019.06.020
  
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sciencedirect.com/science/article/pii/S2211124719307867
Nov 2018
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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

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1. scibot 05 Nov 2018
  
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  RRID:AB_2218658
  
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sciencedirect.com/science/article/pii/S1535610818302186