99 Matching Annotations
  1. Oct 2024
  2. aacrjournals.org aacrjournals.org
    YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
    1
    1. scibot 02 Oct 2024
      RRID:AB_2218913

      DOI: 10.1158/0008-5472.CAN-20-0025

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    aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
    1
    1. scibot 25 Sep 2024
      AB_2218913

      DOI: 10.1016/j.isci.2024.110832

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    sciencedirect.com/science/article/pii/S2589004224020571
  5. Jul 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
    1
    1. scibot 20 Jul 2024
      RRID:AB_2218913

      DOI: 10.1038/s41540-024-00400-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11252164/
  7. www.biorxiv.org www.biorxiv.org
    Bisphenol AF induces overactivation of primordial follicles via Hippo signaling and causes premature ovarian insufficiency in mice
    1
    1. scibot 04 Jul 2024
      RRID:AB_2218913

      DOI: 10.1101/2024.06.19.599666

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    biorxiv.org/content/10.1101/2024.06.19.599666v1
  8. Jun 2024
  9. www.sciencedirect.com www.sciencedirect.com
    PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer
    1
    1. scibot 21 Jun 2024
      RRID:AB_2218913

      DOI: 10.1016/j.cmet.2024.05.015

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    sciencedirect.com/science/article/pii/S1550413124001918
  10. May 2024
  11. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Drive Agrin–Matrix Metalloproteinase-12 Mediated Diabetic Skin Wound Healing
    1
    1. scibot 30 May 2024
      RRID:AB_2218913

      DOI: 10.1016/j.jid.2024.05.005

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    sciencedirect.com/science/article/pii/S0022202X24003919
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell competition drives bronchiolization and pulmonary fibrosis
    1
    1. scibot 23 May 2024
      RRID:AB_2218913

      DOI: 10.21203/rs.3.rs-4177351/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11092845/
  13. Mar 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
    1
    1. scibot 27 Mar 2024
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2024.114003

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    sciencedirect.com/science/article/pii/S2211124724003310
  15. www.nature.com www.nature.com
    Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
    1
    1. scibot 20 Mar 2024
      RRID:AB_2218913

      DOI: 10.1038/s41401-024-01249-0

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    nature.com/articles/s41401-024-01249-0
  16. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
    3
    1. scibot 07 Mar 2024
      RRID:AB_2218913

      DOI: 10.1016/j.isci.2024.109146

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    2. scibot 07 Mar 2024
      RRID:AB_2218913

      DOI: 10.1016/j.isci.2024.109146

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    3. scibot 02 Mar 2024
      RRID:AB_2218913

      DOI: 10.1016/j.isci.2024.109146

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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
    1
    1. scibot 06 Mar 2024
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2024.113927

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    ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
  18. Nov 2023
  19. www.sciencedirect.com www.sciencedirect.com
    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
    1
    1. scibot 28 Nov 2023
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2023.113486

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    sciencedirect.com/science/article/pii/S2211124723014985
  20. Aug 2023
  21. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
    1
    1. scibot 05 Aug 2023
      RRID:AB_2218913

      DOI: 10.1016/j.isci.2023.107449

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    sciencedirect.com/science/article/pii/S2589004223015262
  22. May 2023
  23. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
    1
    1. scibot 05 May 2023
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2022.111077

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    sciencedirect.com/science/article/pii/S2211124722008750
  24. Apr 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.stem.2023.03.005

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    sciencedirect.com/science/article/pii/S1934590923000760
  26. Mar 2023
  27. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
    2
    1. scibot 16 Mar 2023
      RRID:AB_2218913

      DOI: 10.15252/embj.2022112126

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    2. scibot 16 Mar 2023
      RRID:AB_2218913

      DOI: 10.15252/embj.2022112126

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    embopress.org/doi/10.15252/embj.2022112126
  28. Jan 2023
  29. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 14 Jan 2023
      RRID:AB_2218913

      DOI: 10.1111/bph.16007

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16007
  30. Nov 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
    1
    1. scibot 18 Nov 2022
      RRID:AB_2218913

      DOI: 10.1016/j.molcel.2022.10.027

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    sciencedirect.com/science/article/pii/S1097276522010553
  32. www.sciencedirect.com www.sciencedirect.com
    Multiphase coalescence mediates Hippo pathway activation
    1
    1. scibot 03 Nov 2022
      RRID:AB_2218913

      DOI: 10.1016/j.cell.2022.09.036

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    sciencedirect.com/science/article/pii/S0092867422012557
  33. Oct 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.
    1
    1. scibot 27 Oct 2022
      RRID:AB_2218913

      DOI: 10.1016/j.isci.2022.105275

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    ncbi.nlm.nih.gov/pmc/articles/PMC9589172/
  35. elifesciences.org elifesciences.org
    Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury
    1
    1. scibot 19 Oct 2022
      RRID:AB_2218913

      DOI: 10.7554/eLife.78540

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    elifesciences.org/articles/78540
  36. Sep 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
    1
    1. scibot 08 Sep 2022
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2022.111313

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    sciencedirect.com/science/article/pii/S2211124722011378
  38. www.sciencedirect.com www.sciencedirect.com
    Virtual screening for small-molecule pathway regulators by image-profile matching
    1
    1. scibot 07 Sep 2022
      RRID:AB_2218913

      DOI: 10.1016/j.cels.2022.08.003

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    sciencedirect.com/science/article/pii/S2405471222003301
  39. Aug 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
    1
    1. scibot 31 Aug 2022
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2022.111296

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    sciencedirect.com/science/article/pii/S2211124722011160
  41. www.sciencedirect.com www.sciencedirect.com
    Pressure and curvature control of the cell cycle in epithelia growing under spherical confinement
    1
    1. scibot 26 Aug 2022
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2022.111227

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    sciencedirect.com/science/article/pii/S2211124722010440
  42. Jun 2022
  43. www.sciencedirect.com www.sciencedirect.com
    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
    1
    1. scibot 03 Jun 2022
      RRID:AB_2218913

      DOI: 10.1016/j.ebiom.2022.104092

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    sciencedirect.com/science/article/pii/S2352396422002730
  44. May 2022
  45. www.sciencedirect.com www.sciencedirect.com
    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
    1
    1. scibot 13 May 2022
      RRID:AB_2218913

      DOI: 10.1016/j.isci.2022.104316

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    sciencedirect.com/science/article/pii/S2589004222005879
  46. Apr 2022
  47. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
    1
    1. scibot 20 Apr 2022
      RRID:AB_2218913

      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  48. Jan 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
    1
    1. scibot 26 Jan 2022
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2021.110227

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    sciencedirect.com/science/article/pii/S2211124721017319
  50. Dec 2021
  51. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
    1
    1. scibot 21 Dec 2021
      RRID:AB_2218913

      DOI: 10.1038/s41467-021-27452-9

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    nature.com/articles/s41467-021-27452-9
  52. Oct 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas
    1
    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109873

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    sciencedirect.com/science/article/pii/S2211124721013401
  54. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Early resistance training-mediated stimulation of daily muscle protein synthetic responses to higher habitual protein intake in middle-aged adults
    1
    1. scibot 20 Oct 2021
      RRID:AB_2218913

      DOI: 10.1113/JP281907

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP281907
  55. www.sciencedirect.com www.sciencedirect.com
    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice
    1
    1. scibot 05 Oct 2021
      RRID:AB_2218913

      DOI: 10.1016/j.devcel.2021.09.008

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    sciencedirect.com/science/article/pii/S1534580721007267
  56. Aug 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
    1
    1. scibot 28 Aug 2021
      RRID:AB_2218913

      DOI: 10.1016/j.molcel.2021.07.040

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    sciencedirect.com/science/article/pii/S1097276521006249
  58. www.sciencedirect.com www.sciencedirect.com
    Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
    1
    1. scibot 18 Aug 2021
      RRID:AB_2218913

      DOI: 10.1016/j.devcel.2021.07.019

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    sciencedirect.com/science/article/pii/S153458072100602X
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 10 Aug 2021
      RRID:AB_2218913

      DOI: 10.1016/j.cub.2018.11.066

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    ncbi.nlm.nih.gov/pmc/articles/PMC6345631/
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 06 Aug 2021
      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2018.10.024

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    sciencedirect.com/science/article/pii/S2211124718316000
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
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      DOI: 10.1016/j.celrep.2019.03.091

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  62. Jul 2021
  63. www.nature.com www.nature.com
    Treatment of type 2 diabetes with the designer cytokine IC7Fc
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      phosphorylated YAP1(Ser127)

      DOI: 10.1038/s41586-019-1601-9

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  64. www.sciencedirect.com www.sciencedirect.com
    The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
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      RRID:AB_2218913

      DOI: 10.1016/j.devcel.2018.09.021

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  65. dev.biologists.org dev.biologists.org
    Yap and its subcellular localization have distinct compartment-specific roles in the developing lung
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      rabbit anti-pYap

      DOI: 10.1242/dev.175810

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2018.10.024

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  67. May 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Copy number aberrations drive kinase rewiring, leading to genetic vulnerabilities in cancer
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      DOI: 10.1016/j.celrep.2021.109155

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    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
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      DOI: 10.1016/j.chom.2021.04.006

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    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
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      AB_2218913

      DOI: 10.1016/j.molcel.2021.01.010

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    Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells
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      RRID:AB_2218913

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  72. Apr 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
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  74. Mar 2021
  75. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
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      anti‐phospho‐YAP

      DOI: 10.1096/fj.202001909R

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  76. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  77. Nov 2020
  78. www.frontiersin.org www.frontiersin.org
    Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway
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      RRID:AB_2218913

      DOI: 10.3389/fendo.2020.579161

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  79. Oct 2020
  80. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2020.108284

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  81. Sep 2020
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    Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2020.107828

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    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2020.107860

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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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      RRID:AB_2218913

      DOI: 10.1158/0008-5472.CAN-18-4075

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    Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
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      RRID:AB_2218913

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  86. elifesciences.org elifesciences.org
    Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade
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      RRID:AB_2218913

      DOI: 10.7554/eLife.43996

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    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2020.107990

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    Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis
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      RRID:AB_2218913

      DOI: 10.1016/j.devcel.2020.02.015

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
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      RRID:AB_2218913

      DOI: 10.7554/eLife.52779

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    Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development
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      RRID:AB_2218913

      DOI: 10.1016/j.devcel.2020.02.003

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  91. Jan 2020
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    The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2019.10.057

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    The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2019.07.107

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    The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes
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      RRID:AB_2218913

      DOI: 10.1016/j.celrep.2019.05.071

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  95. elifesciences.org elifesciences.org
    CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity
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      RRID:AB_2218913

      DOI: 10.7554/eLife.46012

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    Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells
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      RRID:AB_2218913

      DOI: 10.1016/j.devcel.2019.05.024

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      DOI: 10.1016/j.celrep.2019.03.091

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    The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming
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      DOI: 10.1016/j.celrep.2019.04.047

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      DOI: 10.1016/j.cub.2018.11.066

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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
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    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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    Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation
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  109. Nov 2018
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    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  112. www.sciencedirect.com www.sciencedirect.com
    SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis
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  113. www.sciencedirect.com www.sciencedirect.com
    Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export
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      RRID:AB_2218913

      Curator: @evieth

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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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  115. www.sciencedirect.com www.sciencedirect.com
    Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development
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  116. www.sciencedirect.com www.sciencedirect.com
    Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues
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  117. www.sciencedirect.com www.sciencedirect.com
    β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
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  118. www.sciencedirect.com www.sciencedirect.com
    Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores
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  119. Nov 2017
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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  121. www.sciencedirect.com www.sciencedirect.com
    The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
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  122. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
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  123. www.sciencedirect.com www.sciencedirect.com
    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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  124. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
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  126. www.sciencedirect.com www.sciencedirect.com
    Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
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      AB_2218913

      Curator: @gabimpine

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    Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion
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      AB_2218913

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  129. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    LIX1 regulates YAP1 activity and controls the proliferation and differentiation of stomach mesenchymal progenitors
    1
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      AB_2218913

      Curator: @gabimpine

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