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Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma

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  DOI: 10.1158/0008-5472.CAN-25-2684
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12974268/
Feb 2026
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The serotonin receptor 2b (5-HT2B) modulates heart remodeling following myocardial infarction via regulation of Hippo pathway

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114825
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12915196/
Jan 2026
pubs.acs.org pubs.acs.org

Improving Nonviral Gene Delivery by Activating Mechanosensing-Dependent Endocytic Pathways

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1. scibot 15 Jan 2026
  
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  DOI: 10.1021/acsami.5c23767
  
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pubs.acs.org/doi/full/10.1021/acsami.5c23767
Nov 2025
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Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116620
  
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sciencedirect.com:5037/science/article/pii/S2211124725013920
54.241.53.176 54.241.53.176

2025.11.18.688276v1.full-html.html

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  DOI: 10.1101/2025.11.18.688276
  
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54.241.53.176/3f8f90446ed256aca5958a2ac463bb4ef210a65a/2025.11.18.688276v1.full-html.html
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PKN2 is a dependency of the mesenchymal-like cancer cell state

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  DOI: 10.1158/2159-8290.CD-24-0928
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
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Recycling endosomes in mature epithelia restrain tumorigenic signaling

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  DOI: 10.1158/0008-5472.CAN-18-4075
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6726494/
Aug 2025
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BPS Publications

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1. scibot 01 Aug 2025
  
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  DOI: 10.1111/bph.70137
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70137
Jul 2025
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Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids

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1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113023
  
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sciencedirect.com/science/article/pii/S2589004225012842
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The Hippo pathway kinase MST1 mediates a feedback loop to maintain NLRP3 inflammasome homeostasis

1
1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116076
  
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sciencedirect.com/science/article/pii/S2211124725008472
52.53.155.43 52.53.155.43

Postabsorptive and postprandial myofibrillar protein synthesis rates at rest and after resistance exercise in women with post-menopause

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1. scibot 23 Jul 2025
  
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  DOI: 10.1152/japplphysiol.00886.2023
  
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52.53.155.43/c621f6fdd0b0ae98562b5c2c70d20e1e6e100deb/mckenna-et-al-2024-postabsorptive-and-postprandial-myofibrillar-protein-synthesis-rates-at-rest-and-after-resistance-html.html
Jun 2025
www.sciencedirect.com www.sciencedirect.com

RIPK4 promotes epidermal differentiation through phase separation and activation of LATS1/2

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.devcel.2025.05.017
  
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sciencedirect.com/science/article/pii/S1534580725003284
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A first-in-class EGFR-directed KRAS G12V selective inhibitor

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.05.016
  
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sciencedirect.com/science/article/pii/S1535610825002259
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cell competition drives bronchiolization and pulmonary fibrosis

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1. scibot 11 Dec 2024
  
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  DOI: 10.1038/s41467-024-54997-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11621346/
Oct 2024
aacrjournals.org aacrjournals.org

YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma

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1. scibot 02 Oct 2024
  
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  DOI: 10.1158/0008-5472.CAN-20-0025
  
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aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
Sep 2024
www.sciencedirect.com www.sciencedirect.com

CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110832
  
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sciencedirect.com/science/article/pii/S2589004224020571
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation

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1. scibot 20 Jul 2024
  
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  DOI: 10.1038/s41540-024-00400-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11252164/
www.biorxiv.org www.biorxiv.org

Bisphenol AF induces overactivation of primordial follicles via Hippo signaling and causes premature ovarian insufficiency in mice

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1. scibot 04 Jul 2024
  
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  RRID:AB_2218913
  
  DOI: 10.1101/2024.06.19.599666
  
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biorxiv.org/content/10.1101/2024.06.19.599666v1
Jun 2024
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PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.05.015
  
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sciencedirect.com/science/article/pii/S1550413124001918
May 2024
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YAP/TAZ Drive Agrin–Matrix Metalloproteinase-12 Mediated Diabetic Skin Wound Healing

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.jid.2024.05.005
  
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sciencedirect.com/science/article/pii/S0022202X24003919
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cell competition drives bronchiolization and pulmonary fibrosis

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1. scibot 23 May 2024
  
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  DOI: 10.21203/rs.3.rs-4177351/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11092845/
Mar 2024
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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.114003
  
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sciencedirect.com/science/article/pii/S2211124724003310
www.nature.com www.nature.com

Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway

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1. scibot 20 Mar 2024
  
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  RRID:AB_2218913
  
  DOI: 10.1038/s41401-024-01249-0
  
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nature.com/articles/s41401-024-01249-0
www.cell.com www.cell.com

Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.

3
1. scibot 07 Mar 2024
  
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  RRID:AB_2218913
  
  DOI: 10.1016/j.isci.2024.109146
  
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2. scibot 07 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109146
  
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  DOI: 10.1016/j.isci.2024.109146
  
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cell.com/iscience/abstract/S2589-0042(24)00367-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ALK upregulates POSTN and WNT signaling to drive neuroblastoma

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113927
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
Nov 2023
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p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113486
  
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sciencedirect.com/science/article/pii/S2211124723014985
Aug 2023
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The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

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1. scibot 05 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107449
  
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sciencedirect.com/science/article/pii/S2589004223015262
May 2023
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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.celrep.2022.111077
  
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sciencedirect.com/science/article/pii/S2211124722008750
Apr 2023
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Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation

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  DOI: 10.1016/j.stem.2023.03.005
  
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sciencedirect.com/science/article/pii/S1934590923000760
Mar 2023
www.embopress.org www.embopress.org

Two Hippo signaling modules orchestrate liver size and tumorigenesis

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1. scibot 16 Mar 2023
  
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  DOI: 10.15252/embj.2022112126
  
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2. scibot 16 Mar 2023
  
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  DOI: 10.15252/embj.2022112126
  
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embopress.org/doi/10.15252/embj.2022112126
Jan 2023
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 14 Jan 2023
  
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  DOI: 10.1111/bph.16007
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16007
Nov 2022
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Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis

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1. scibot 18 Nov 2022
  
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  DOI: 10.1016/j.molcel.2022.10.027
  
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sciencedirect.com/science/article/pii/S1097276522010553
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Multiphase coalescence mediates Hippo pathway activation

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1. scibot 03 Nov 2022
  
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  RRID:AB_2218913
  
  DOI: 10.1016/j.cell.2022.09.036
  
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sciencedirect.com/science/article/pii/S0092867422012557
Oct 2022
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A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.

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Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

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Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis

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Virtual screening for small-molecule pathway regulators by image-profile matching

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Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers

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Pressure and curvature control of the cell cycle in epithelia growing under spherical confinement

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YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer

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JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation

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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

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Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion

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A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

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Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas

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Early resistance training-mediated stimulation of daily muscle protein synthetic responses to higher habitual protein intake in middle-aged adults

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Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

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Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

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Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition

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Treatment of type 2 diabetes with the designer cytokine IC7Fc

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  phosphorylated YAP1(Ser127)
  
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The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number

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Yap and its subcellular localization have distinct compartment-specific roles in the developing lung

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Copy number aberrations drive kinase rewiring, leading to genetic vulnerabilities in cancer

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Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis

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Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation

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Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells

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Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer

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The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner

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BPS Publications

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Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway

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A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis

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Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair

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MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation

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Recycling endosomes in mature epithelia restrain tumorigenic signaling

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Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness

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Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade

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Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis

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Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis

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Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin

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Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development

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The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells

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The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

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The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes

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CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity

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Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells

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The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming

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FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis

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OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

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Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation

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Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction

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SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis

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Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development

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Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues

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β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer

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Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

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YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis

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Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1535610817301599
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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
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sciencedirect.com/science/article/pii/S2405471216304082
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An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
  Curator: @ifroman
  
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sciencedirect.com/science/article/pii/S1934590917300942
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Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1534580717301156
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YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5360446/
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Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
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LIX1 regulates YAP1 activity and controls the proliferation and differentiation of stomach mesenchymal progenitors

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1. scibot 08 Nov 2017
  
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  AB_2218913
  
  Curator: @gabimpine
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0257-2

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