Hypothesis

32 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

Acetate suppresses tumorigenesis through ACSS2-dependent H2A.Z acetylation in esophageal squamous cell carcinoma

1
1. scibot 23 Aug 2026
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2026.117892
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726009708
Jul 2026
www.sciencedirect.com www.sciencedirect.com

ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatment

1
1. scibot 22 Jul 2026
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.isci.2026.116860
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004226022388
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ACSS2 Suppresses Ferroptosis to Drive Breast Cancer Brain Metastasis

1
1. scibot 06 Jun 2026
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1158/0008-5472.CAN-25-3006
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13195636/
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Mitochondrial ACSS1 links acetate metabolism to pyrimidine biosynthesis in nutrient-stressed B-cell lymphomas

1
1. scibot 09 Apr 2026
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.canlet.2026.218488
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S030438352600251X
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of a common ketohexokinase-dependent link driving alcohol intake and alcohol-associated liver disease in mice

1
1. scibot 26 Nov 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1038/s42255-025-01402-x
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12638252/
Oct 2025
www.biorxiv.org www.biorxiv.org

ACSS2-Mediated Metabolic-Epigenetic Crosstalk Drives Fulvestrant Resistance and Represents a Novel Therapeutic Target

1
1. scibot 14 Oct 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1101/2025.09.23.678089
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.09.23.678089v1
Sep 2025
www.biorxiv.org www.biorxiv.org

Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells

1
1. scibot 12 Sep 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1101/2025.08.20.671247
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.08.20.671247v1
www.biorxiv.org www.biorxiv.org

Mitochondrial ACSS1 Links Acetate Metabolism to Pyrimidine Biosynthesis in Nutrient-Stressed B-Cell Lymphomas

1
1. scibot 09 Sep 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1101/2025.08.29.673065
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.08.29.673065v1
Jul 2025
www.cell.com www.cell.com

High fructose promotes MYCN-amplified neuroblastoma progression through NgBR-ACSS2-mediated biosynthesis of acetyl-CoA

1
1. scibot 08 Jul 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2025.115947
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(25)00718-1
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation

1
1. scibot 22 May 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2025.115444
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12091147/
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis

1
1. scibot 11 Feb 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2025.115284
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725000555
Jan 2025
www.sciencedirect.com www.sciencedirect.com

A genetically encoded fluorescent biosensor for visualization of acetyl-CoA in live cells

1
1. scibot 28 Jan 2025
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.chembiol.2025.01.002
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945625000029
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2024.115015
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724013664
www.sciencedirect.com www.sciencedirect.com

ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2024.114988
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724013391
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma

1
1. scibot 18 Jul 2024
  
  in Public
  
  AB_2222710
  
  DOI: 10.1016/j.celrep.2024.114406
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11290356/
www.biorxiv.org www.biorxiv.org

ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart

1
1. scibot 04 Jul 2024
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1101/2024.06.21.600099
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

biorxiv.org/content/10.1101/2024.06.21.600099v1
Mar 2024
link.springer.com link.springer.com

Transcriptional and metabolic effects of aspartate-glutamate carrier isoform 1 (AGC1) downregulation in mouse oligodendrocyte precursor cells (OPCs)

1
1. scibot 30 Mar 2024
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1186/s11658-024-00563-z
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

link.springer.com/article/10.1186/s11658-024-00563-z
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression

1
1. scibot 11 Jan 2024
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2023.113575
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723015875
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1158/0008-5472.CAN-22-3450
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Acetate controls endothelial-to-mesenchymal transition

1
1. scibot 21 Jun 2023
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.cmet.2023.05.010
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413123002036
52.53.155.43 52.53.155.43

can-22-3450-html.html

1
1. scibot 01 Jun 2023
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1158/0008-5472.can-22-3450
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

52.53.155.43/d74c78a2e62f04f8ffa00018470c131fb0d65945/can-22-3450-html.html
www.sciencedirect.com www.sciencedirect.com

The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming

1
1. scibot 01 Jun 2023
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2023.112590
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723006010
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis

1
1. scibot 18 Nov 2022
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.molcel.2022.10.027
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522010553
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes

1
1. scibot 02 Aug 2022
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2022.111146
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472200955X
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

1
1. scibot 08 Jun 2022
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.cmet.2022.05.004
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413122001863
May 2022
www.sciencedirect.com www.sciencedirect.com

Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy

1
1. scibot 11 May 2022
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2022.110796
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722005630
Dec 2021
reader.elsevier.com reader.elsevier.com

Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells

1
1. scibot 01 Dec 2021
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.celrep.2021.110063
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

reader.elsevier.com/reader/sd/pii/S2211124721015497
May 2021
www.sciencedirect.com www.sciencedirect.com

Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.stem.2020.12.009
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590920305932
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:AB_2222710
  
  DOI: 10.1016/j.cmet.2020.12.011
  
  Resource: (Cell Signaling Technology Cat# 3658, RRID:AB_2222710)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2222710
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413120306665
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2222710
  
  Curator: @Jmenke
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3658S, RRID:AB_2222710)
  
  SciCrunch record: RRID:AB_2222710
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2222710 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2222710

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418311012
www.sciencedirect.com www.sciencedirect.com

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2222710
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3658S, RRID:AB_2222710)
  
  SciCrunch record: RRID:AB_2222710
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2222710
Visit annotations in context

Tags

RRID:AB_2222710

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413117306204
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_2222710
  
  Curator: @patriciaelyse_
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3658S, RRID:AB_2222710)
  
  SciCrunch record: RRID:AB_2222710
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2222710 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2222710

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867417308784