444 Matching Annotations
  1. Aug 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12335601/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel roles for the GPI-anchor cleaving enzyme, GDE2, in hippocampal synaptic morphology and function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12320762/
  4. Jul 2025
  5. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225014907-main-html.html
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    1-s2.0-S092544392500081X-mmc1-html.html
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  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cinnabarinic acid protects against metabolic dysfunction-associated steatohepatitis by activating Aryl hydrocarbon Receptor-dependent AMPK signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12258133/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12258067/
  9. Jun 2025
  10. www.sciencedirect.com www.sciencedirect.com
    The human neural cell atlas of Zika virus infection in developing brain tissue
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    sciencedirect.com/science/article/pii/S2666379125002629
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    Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression
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    sciencedirect.com/science/article/pii/S2211124725006370
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12240685/
  13. 52.53.155.43 52.53.155.43
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    Pro-ferroptotic lipids as key control points for caveola formation and disassembly
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    cell.com/cell-reports/fulltext/S2211-1247(25)00560-1
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    Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS
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    sciencedirect.com/science/article/pii/S0092867425005562
  16. May 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expression of Mitochondrial Uncoupling Proteins and GABA Signaling Molecules in Unstimulated and Nerve Growth Factor–Stimulated PC12 Cells: Models for Chromaffin Cells and Sympathetic Neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037542/
  18. Apr 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurotensin Regulates Primate Ovulation Via Multiple Neurotensin Receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11979100/
  20. 52.53.155.43 52.53.155.43
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    Structural basis of BAK sequestration by MCL-1 in apoptosis
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    sciencedirect.com/science/article/pii/S1097276525002515
  22. elifesciences.org elifesciences.org
    Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis
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    elifesciences.org/articles/94930
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI4P-mediated solid-like Merlin condensates orchestrate Hippo pathway regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11956869/
  24. 52.53.155.43 52.53.155.43
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  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Interferon-Inducible ADAR1 p150 Is Essential for the Survival of Oral Squamous Cell Carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/mc.23910
  26. Mar 2025
  27. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70015
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microglia clonal inflammatory disorder in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908784/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11906863/
  30. www.biorxiv.org www.biorxiv.org
    Identification of the Lipid Oxygen Radical Defense pathway and its epigenetic control
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    biorxiv.org/content/10.1101/2025.02.25.640160v1
  31. Feb 2025
  32. www.sciencedirect.com www.sciencedirect.com
    MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling
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    sciencedirect.com/science/article/pii/S1550413125000178
  33. dx.doi.org dx.doi.org
    Identification of succinate dehydrogenase gene variant carriers by blood biomarkers
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    dx.doi.org/10.1210/jendso/bvae142
  34. aacrjournals.org aacrjournals.org
    Adenosine-deaminase-acting-on-RNA-1 facilitates T-cell migration toward human melanoma cells
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    aacrjournals.org/cancerimmunolres/article/10/9/1127/708044/Adenosine-Deaminase-Acting-on-RNA-1-Facilitates-T
  35. aacrjournals.org aacrjournals.org
    C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia
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    aacrjournals.org/cancerdiscovery/article/13/7/1720/727640/C-EBP-Confers-Dependence-to-Fatty-Acid-Anabolic
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oxidative Stress Suppresses Trk Signaling While Stimulating JNK-Mediated Endocytosis and Cleavage of p75NTR: A Targetable Pathway for Neuroprotection in a Parkinson's Disease Model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70010
  37. 52.53.155.43 52.53.155.43
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    Exposure of negative-sense viral RNA in the cytoplasm initiates innate immunity to West Nile virus
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    Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson’s disease via the prosaposin-GPR37-IL-6 axis
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    sciencedirect.com/science/article/pii/S2211124725000373
  40. Jan 2025
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17443
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831618/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A transcription network underlies the dual genomic coordination of mitochondrial biogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11677238/
  44. www.nature.com www.nature.com
    Abnormal cytoskeletal remodeling but normal neuronal excitability in a mouse model of the recurrent developmental and epileptic encephalopathy-susceptibility KCNB1-p.R312H variant
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    nature.com/articles/s42003-024-07344-6
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    Cyclin switch tailors a cell cycle variant to orchestrate multiciliogenesis
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    sciencedirect.com/science/article/pii/S2211124724014542
  46. Dec 2024
  47. www.sciencedirect.com www.sciencedirect.com
    3D chromatin hubs as regulatory units of identity and survival in human acute leukemia
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    sciencedirect.com/science/article/pii/S109727652400995X
  48. elifesciences.org elifesciences.org
    Control of 3′ splice site selection by the yeast splicing factor Fyv6
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    elifesciences.org/articles/100449
  49. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17402
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    1-s2.0-S2589004224027901-main-html.html
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  51. www.sciencedirect.com www.sciencedirect.com
    Transposable element exonization generates a reservoir of evolving and functional protein isoforms
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    sciencedirect.com/science/article/pii/S009286742401328X
  52. link.springer.com link.springer.com
    Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer
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    link.springer.com/article/10.1007/s10456-024-09956-2
  53. Nov 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Plausible, robust biological oscillations through allelic buffering
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    sciencedirect.com/science/article/pii/S2405471224002990
  55. www.sciencedirect.com www.sciencedirect.com
    PI3K/Akt inhibition promotes AR activity and prostate cancer cell proliferation through p35-CDK5 modulation
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    sciencedirect.com/science/article/pii/S0925443924005623
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of estrogen-related receptor γ by calcium and cadmium
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537906/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11475318/
  58. Oct 2024
  59. www.sciencedirect.com www.sciencedirect.com
    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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    sciencedirect.com/science/article/pii/S2211124724011483
  60. Sep 2024
  61. www.biorxiv.org www.biorxiv.org
    LM11a-31 Inhibits p75 Neurotrophin Receptor (p75NTR) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson’s Disease
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    biorxiv.org/content/10.1101/2024.09.10.612299v1
  62. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Sodium butyrate prevents cytokine-induced β-cell dysfunction through restoration of stromal interaction molecule 1 expression and activation of store-operated calcium entry
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302501RR
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unlocking the Secrets of Adipose Tissue: How an Obesity-Associated Secretome Promotes Osteoblast Dedifferentiation via TGF-β1 Signaling, Paving the Path to an Adipogenic Phenotype
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394205/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear actin is a critical regulator of Drosophila female germline stem cell maintenance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383290/
  65. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  66. Aug 2024
  67. www.sciencedirect.com www.sciencedirect.com
    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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    sciencedirect.com/science/article/pii/S266637912400421X
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cadmium activation of wild-type and constitutively active estrogen receptor alpha
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341946/
  69. www.sciencedirect.com www.sciencedirect.com
    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
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    sciencedirect.com/science/article/pii/S1097276524005896
  70. www.embopress.org www.embopress.org
    LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis
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    embopress.org/doi/full/10.15252/embr.202051289
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice
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    onlinelibrary.wiley.com/doi/10.1002/glia.22756/full
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network
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    ncbi.nlm.nih.gov/pmc/articles/PMC11288008/
  73. Jul 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10962759/
  75. 52.53.155.43 52.53.155.43
    Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells
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    52.53.155.43/cf6c0d0512288d47755548d278f58be4dccbb32c/jcs258391supp-html.html
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
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    ncbi.nlm.nih.gov/pmc/articles/PMC10146492/
  77. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
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    elifesciences.org/articles/98649
  78. www.sciencedirect.com www.sciencedirect.com
    Local vascular Klotho mediates diabetes-induced atherosclerosis via ERK1/2 and PI3-kinase-dependent signaling pathways.
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    sciencedirect.com/science/article/pii/S0021915024010992
  79. www.biorxiv.org www.biorxiv.org
    Aromatase in adipose tissue exerts an osteoprotective function in male mice via phosphate regulation
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    biorxiv.org/content/10.1101/2024.06.24.600344v2
  80. Jun 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166698/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC11167442/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase
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    ncbi.nlm.nih.gov/pmc/articles/PMC11164532/
  84. May 2024
  85. www.sciencedirect.com www.sciencedirect.com
    RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly
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    sciencedirect.com/science/article/pii/S0092867424004689
  86. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Postsynaptic β1 spectrin maintains Na+ channels at the neuromuscular junction
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285894
  87. www.sciencedirect.com www.sciencedirect.com
    TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
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    sciencedirect.com/science/article/pii/S2211124724005424
  88. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  89. www.cell.com www.cell.com
    Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders
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    cell.com/iscience/abstract/S2589-0042(24)01024-1
  90. 52.53.155.43 52.53.155.43
    Eicosapentaenoic acid increases proportion of type1 muscle fibers through PPARδ and AMPK pathways in rats
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    52.53.155.43/ef2eb540c316e37b8125f79aafdc12a777c8d945/PIIS2589004224010381-html.html
  91. Apr 2024
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
  93. www.sciencedirect.com www.sciencedirect.com
    Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans
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    sciencedirect.com/science/article/pii/S1534580724002302
  94. link.springer.com link.springer.com
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    link.springer.com/article/10.1038/s41594-024-01294-7
  95. www.sciencedirect.com www.sciencedirect.com
    Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis
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    sciencedirect.com/science/article/pii/S2352396424001373
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10985479/
  98. Mar 2024
  99. www.sciencedirect.com www.sciencedirect.com
    PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication
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    sciencedirect.com/science/article/pii/S2451945624000783
  100. www.sciencedirect.com www.sciencedirect.com
    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    sciencedirect.com/science/article/pii/S109727652400176X
  101. link.springer.com link.springer.com
    Intestinal dual-specificity phosphatase 6 regulates the cold-induced gut microbiota remodeling to promote white adipose browning
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    link.springer.com/article/10.1038/s41522-024-00495-8
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  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases
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  210. www.nature.com www.nature.com
    White matter integrity in mice requires continuous myelin synthesis at the inner tongue
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  211. Feb 2022
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    Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy
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    Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting
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    Unconcerted conformational changes in Arp2/3 complex integrate multiple activating signals to assemble functional actin networks
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  215. Jan 2022
  216. elifesciences.org elifesciences.org
    Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection
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    miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated α-tubulin K394 regulates microtubule stability to shape the growth of axon terminals
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    WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
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    The portrait of liver cancer is shaped by mitochondrial genetics
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  221. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models
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  222. Dec 2021
  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Usher syndrome Type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish
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    14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice
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    Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production
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  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
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  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A
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  228. Nov 2021
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    The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function
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  230. Oct 2021
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    Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing
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    The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment
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    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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    Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice
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    Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
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  236. Sep 2021
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    Real-time monitoring of deformed wing virus-infected bee foraging behavior following histone deacetylase inhibitor treatment
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    Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
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    UQCRC1 engages cytochrome c for neuronal apoptotic cell death
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