582 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation
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    1. scibot 14 Nov 2024
      RRID:AB_2223172

      DOI: 10.1016/j.isci.2024.111186

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    pmc.ncbi.nlm.nih.gov/articles/PMC11550584/
  3. www.sciencedirect.com www.sciencedirect.com
    Degradome analysis to identify direct protein substrates of small-molecule degraders
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    1. scibot 14 Nov 2024
      RRID:AB_2223172

      DOI: 10.1016/j.chembiol.2024.10.007

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    sciencedirect.com/science/article/pii/S2451945624004422
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β2-integrins control HIF1α activation in human neutrophils
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    1. scibot 07 Nov 2024
      RRID:AB_2223172

      DOI: 10.3389/fimmu.2024.1406967

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513320/
  5. Oct 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
    1
    1. scibot 02 Oct 2024
      RRID:AB_2223172

      DOI: 10.4103/NRR.NRR-D-23-01299

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    ncbi.nlm.nih.gov/pmc/articles/PMC11438333/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-preconditioned bone marrow–derived mesenchymal stem cells protect neurons from cardiac arrest–induced pyroptosis
    1
    1. scibot 02 Oct 2024
      RRID:AB_2223172

      DOI: 10.4103/NRR.NRR-D-23-01922

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    ncbi.nlm.nih.gov/pmc/articles/PMC11438345/
  8. Sep 2024
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pharmacologic activation of activating transcription factor 6 contributes to neuronal survival after spinal cord injury in mice
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    1. scibot 27 Sep 2024
      RRID:AB_2223172

      DOI: 10.1111/jnc.16092

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16092
  10. www.sciencedirect.com www.sciencedirect.com
    Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing
    1
    1. scibot 25 Sep 2024
      RRID:AB_2223172

      DOI: 10.1016/j.scr.2020.102135

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    sciencedirect.com/science/article/pii/S1873506120304360
  11. www.sciencedirect.com www.sciencedirect.com
    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
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    1. scibot 25 Sep 2024
      RRID:AB_10694076

      DOI: 10.1016/j.ccell.2020.03.001

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    sciencedirect.com/science/article/pii/S153561082030101X
  12. www.sciencedirect.com www.sciencedirect.com
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    1
    1. scibot 25 Sep 2024
      RRID:AB_2223172

      DOI: 10.1016/j.stem.2020.02.007

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    sciencedirect.com/science/article/pii/S1934590920300606
  13. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of Piezo1 at a single residue, serine-1612, regulates its mechanosensitivity and in vivo mechanotransduction function
    1
    1. scibot 13 Sep 2024
      AB_2223172

      DOI: 10.1016/j.neuron.2024.08.009

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    sciencedirect.com/science/article/pii/S0896627324005816
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells
    1
    1. scibot 13 Sep 2024
      RRID:AB_2223172

      DOI: 10.3390/ijms25168595

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    ncbi.nlm.nih.gov/pmc/articles/PMC11354993/
  15. www.sciencedirect.com www.sciencedirect.com
    m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1
    1
    1. scibot 10 Sep 2024
      RRID:AB_2223172

      DOI: 10.1016/j.cmet.2024.08.006

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    sciencedirect.com/science/article/pii/S1550413124003334
  16. www.sciencedirect.com www.sciencedirect.com
    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
    1
    1. scibot 04 Sep 2024
      AB_2223172

      DOI: 10.1016/j.xcrm.2024.101711

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    sciencedirect.com/science/article/pii/S2666379124004324
  17. Aug 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice
    1
    1. scibot 27 Aug 2024
      RRID:AB_2223172

      DOI: 10.1038/s41467-024-51030-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11344041/
  19. www.sciencedirect.com www.sciencedirect.com
    A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
    1
    1. scibot 22 Aug 2024
      RRID:AB_2223172

      DOI: 10.1016/j.cell.2024.07.038

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    sciencedirect.com/science/article/pii/S0092867424008328
  20. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
    1
    1. scibot 22 Aug 2024
      RRID:AB_2223172

      DOI: 10.1016/j.celrep.2024.114622

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    sciencedirect.com/science/article/pii/S2211124724009720
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.ccell.2024.07.005

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    sciencedirect.com/science/article/pii/S1535610824002708
  22. www.sciencedirect.com www.sciencedirect.com
    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
    1
    1. scibot 20 Aug 2024
      AB_2223172

      DOI: 10.1016/j.celrep.2024.114608

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    sciencedirect.com/science/article/pii/S2211124724009586
  23. www.sciencedirect.com www.sciencedirect.com
    Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
    1
    1. scibot 20 Aug 2024
      RRID:AB_2223172

      DOI: 10.1016/j.chembiol.2024.07.005

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    sciencedirect.com/science/article/pii/S2451945624003076
  24. www.sciencedirect.com www.sciencedirect.com
    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
    1
    1. scibot 19 Aug 2024
      AB_2223172

      DOI: 10.1016/j.isci.2024.110499

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    sciencedirect.com/science/article/pii/S2589004224017243
  25. www.sciencedirect.com www.sciencedirect.com
    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
    1
    1. scibot 19 Aug 2024
      AB_2223172

      DOI: 10.1016/j.jep.2024.118650

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    sciencedirect.com/science/article/pii/S0378874124009498
  26. www.authorea.com www.authorea.com
    Preliminary exploration of endoplasmic reticulum stress transmission in astrocytes and neurons, and its mediators
    1
    1. scibot 18 Aug 2024
      AB_2223172

      DOI: 10.22541/au.172258066.64851176/v1

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    authorea.com/users/811586/articles/1213019-preliminary-exploration-of-endoplasmic-reticulum-stress-transmission-in-astrocytes-and-neurons-and-its-mediators
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
    1
    1. scibot 18 Aug 2024
      RRID:AB_2223172

      DOI: 10.3389/fonc.2024.1431362

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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Frontiers | The Nonvesicular Sterol Transporter Aster-C Plays a Minor Role in Whole Body Cholesterol Balance
    1
    1. scibot 13 Aug 2024
      Cell Signaling Technologies product # 4970S

      DOI: 10.3389/fphys.2024.1371096

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      RRID:AB_2223172 DOI:10.3389/fphys.2024.1371096
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    pmc.ncbi.nlm.nih.gov/articles/PMC11061533/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy
    1
    1. scibot 13 Aug 2024
      RRID:AB_2223172

      DOI: 10.1038/s41598-024-57926-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10994939/
  30. www.researchsquare.com www.researchsquare.com
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    1. scibot 02 Aug 2024
      RRID:AB_2223172

      DOI: 10.21203/rs.3.rs-1982889/v1

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  31. Jul 2024
  32. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
    1
    1. scibot 31 Jul 2024
      AB_2223172

      DOI: 10.1016/j.celrep.2024.114565

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    sciencedirect.com/science/article/pii/S2211124724008945
  33. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    1. scibot 30 Jul 2024
      RRID:AB_2223172

      DOI: 10.1016/j.chom.2024.07.001

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00254-3
  34. www.sciencedirect.com www.sciencedirect.com
    Impaired phase separation and nucleolar functions in hiPSC models of SNORD118-related ribosomopathies
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.isci.2024.110430

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    sciencedirect.com/science/article/pii/S2589004224016559
  35. www.sciencedirect.com www.sciencedirect.com
    Multi-step regulation of microRNA expression and secretion into small extracellular vesicles by insulin
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    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114491

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    sciencedirect.com/science/article/pii/S2211124724008209
  36. link.springer.com link.springer.com
    Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model
    1
    1. scibot 09 Jul 2024
      AB_2223172

      DOI: 10.1007/s10735-024-10192-7

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    link.springer.com/article/10.1007/s10735-024-10192-7
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors
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    1. scibot 06 Jul 2024
      RRID:AB_2223172

      DOI: 10.1158/1535-7163.MCT-23-0144

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    ncbi.nlm.nih.gov/pmc/articles/PMC11223745/
  38. Jun 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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      DOI: 10.1016/j.devcel.2024.04.020

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    sciencedirect.com/science/article/pii/S1534580724002958
  40. www.sciencedirect.com www.sciencedirect.com
    Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cmet.2024.05.010

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    sciencedirect.com/science/article/pii/S1550413124001864
  41. www.sciencedirect.com www.sciencedirect.com
    PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer
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      DOI: 10.1016/j.cmet.2024.05.015

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    sciencedirect.com/science/article/pii/S1550413124001918
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma
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      DOI: 10.1016/j.isci.2024.109997

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    ncbi.nlm.nih.gov/pmc/articles/PMC11166694/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subpopulation of luminal progenitors secretes pleiotrophin to promote angiogenesis and metastasis in inflammatory breast cancer
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    1. scibot 08 Jun 2024
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      DOI: 10.1158/0008-5472.CAN-23-2640

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148543/
  44. www.sciencedirect.com www.sciencedirect.com
    Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice
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    1. scibot 07 Jun 2024
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      DOI: 10.1016/j.expneurol.2024.114784

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    sciencedirect.com/science/article/pii/S0014488624001109
  45. aacrjournals.org aacrjournals.org
    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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    1. scibot 07 Jun 2024
      RRID:AB_2223172

      DOI: 10.1158/0008-5472.CAN-23-0519

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    Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease
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    Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females
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    KLF4 promotes milk fat synthesis by regulating the PI3K-AKT-mTOR pathway and targeting FASN activation in bovine mammary epithelial cells
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
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    Ovulation provides excessive coagulation and hepatocyte growth factor signals to cause postoperative intraabdominal adhesions
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    Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage
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    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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    ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
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    Increased intestinal bile acid absorption contributes to age-related cognitive impairment
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  60. Apr 2024
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    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
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    Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome
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    SHIP inhibition mediates select TREM2-induced microglial functions
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    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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    The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice
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  69. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling
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  71. Mar 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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    Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier
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    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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    Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis
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  82. www.biorxiv.org www.biorxiv.org
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    Simulated Microgravity Enhances Adipocyte Maturation and Glucose Uptake via Increased Cortical Actin Remodeling
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    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alleviation of monocyte exhaustion by BCG derivative mycolic acid
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    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
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    The mitochondrial genome-encoded peptide MOTS-c interacts with Bcl-2 to alleviate nonalcoholic steatohepatitis progression
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    A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity
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    A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
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    hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    Bruton’s Tyrosine Kinase Inhibitors With Distinct Binding Modes Reveal Differential Functional Impact on B-Cell Receptor Signaling
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    Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction
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  105. Dec 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation
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    Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
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    ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits
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  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nanocurcumin attenuates pyroptosis and inflammation through inhibiting NF-κB/GSDMD signal in high altitude-associated acute liver injury
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    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
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  111. 52.53.155.43 52.53.155.43
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    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
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  114. www.sciencedirect.com www.sciencedirect.com
    In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells
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    Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  123. www.science.org www.science.org
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    Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function
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    Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (−)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice
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  127. Oct 2023
  128. www.sciencedirect.com www.sciencedirect.com
    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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    ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modification of Lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency
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  133. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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  134. www.sciencedirect.com www.sciencedirect.com
    Comprehensive quantification of metabolic flux during acute cold stress in mice
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  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tyrosine hydroxylase phosphorylation is under the control of serine 40
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  136. www.sciencedirect.com www.sciencedirect.com
    Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria
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  137. Sep 2023
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for high-sensitivity western blot on murine hematopoietic stem cells
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  139. www.mdpi.com www.mdpi.com
    Generation of Novel Immunocompetent Mouse Cell Lines to Model Experimental Metastasis of High-Risk Neuroblastoma
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  140. www.sciencedirect.com www.sciencedirect.com
    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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  141. 52.53.155.43 52.53.155.43
    Different sensitivity to diet-induced hyperinsulinemia and hyperglycemia between mice with global or bone marrow-specific apoE receptor-2 deficiency
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  142. 52.53.155.43 52.53.155.43
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  143. www.sciencedirect.com www.sciencedirect.com
    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  147. Aug 2023
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mitotic clonal expansion and thermogenic pathway are involved in the antiadipogenic effects of cyanidin-3-O-glucoside
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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  150. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
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    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
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    IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  157. 52.53.155.43 52.53.155.43
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  158. 52.53.155.43 52.53.155.43
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine
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  161. www.sciencedirect.com www.sciencedirect.com
    Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
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    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
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    High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
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    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis
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  168. 52.53.155.43 52.53.155.43
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  169. www.nature.com www.nature.com
    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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  170. www.embopress.org www.embopress.org
    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
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    Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
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    Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
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    Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression
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    Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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  181. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    (A) Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis
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    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
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    Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7
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  189. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling
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    Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease
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    Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
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    LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation
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    HOTAIR‐Loaded Mesenchymal Stem/Stromal Cell Extracellular Vesicles Enhance Angiogenesis and Wound Healing
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    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response
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    A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
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  205. Mar 2023
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    Mitoguardin2 is Associated with Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells
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    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
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    TRIB2 safeguards naive T cell homeostasis during aging
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  213. www.biorxiv.org www.biorxiv.org
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