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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone marrow monocytes and macrophages from mice lacking βENaC and ASIC2 have a reduced chemotactic migration response and polarization
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    1. scibot 20 Jul 2024
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  3. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017255-main-html.html
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  4. Jun 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia: effects on neurobehavioral phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11168517/
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    Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
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    1. scibot 09 Jun 2024
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      DOI: 10.1016/j.isci.2024.109991

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    1. scibot 06 Jun 2024
      C. Other antibodies used in the study.

      DOI: 10.1101/2022.03.30.486322

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  8. May 2024
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modelling atopic dermatitis in healthy human skin for the characterization of topical compounds
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      DOI: 10.1111/exd.15099

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    onlinelibrary.wiley.com/doi/10.1111/exd.15099
  10. www.biorxiv.org www.biorxiv.org
    Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition
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    1. scibot 16 May 2024
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      DOI: 10.1101/2024.02.22.581507

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    biorxiv.org/content/10.1101/2024.02.22.581507v1
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    Claudin-4 modulates autophagy via SLC1A5/LAT1 as a tolerance mechanism for genomic instability in ovarian cancer
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    1. scibot 03 May 2024
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      DOI: 10.1101/2024.01.18.576263

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    biorxiv.org/content/10.1101/2024.01.18.576263v2
  12. Apr 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors
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    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114143

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    sciencedirect.com/science/article/pii/S2211124724004716
  14. Mar 2024
  15. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
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    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.013

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      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  16. Feb 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer
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    1. scibot 28 Feb 2024
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      DOI: 10.1016/j.isci.2024.108794

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription
    1
    1. scibot 27 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056844/
  19. aacrjournals.org aacrjournals.org
    Osteoclast-Cancer Cell Metabolic Crosstalk Confers PARP Inhibitor Resistance in Bone Metastatic Breast Cancer
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    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-1443

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    aacrjournals.org/cancerres/article/84/3/449/733850/Osteoclast-Cancer-Cell-Metabolic-Cross-talk
  20. link.springer.com link.springer.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    1. scibot 07 Feb 2024
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      DOI: 10.1186/s13059-023-03161-y

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    link.springer.com/article/10.1186/s13059-023-03161-y
  21. Jan 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
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    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.013

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    sciencedirect.com/science/article/pii/S1550413123004643
  23. Dec 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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      DOI: 10.1016/j.ccell.2023.11.010

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    sciencedirect.com/science/article/pii/S1535610823004014
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin alleviates hepatic iron overload and ferroptosis through AMPK-ferroportin pathway in HFD-induced NAFLD
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      DOI: 10.1016/j.isci.2023.108560

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    ncbi.nlm.nih.gov/pmc/articles/PMC10711470/
  26. Nov 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cardiovascular Complications of Pregnancy: Synergistic regulation of uterine radial artery adaptation to pregnancy by paracrine and hemodynamic factors
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      DOI: 10.1152/ajpheart.00205.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10643003/
  28. www.sciencedirect.com www.sciencedirect.com
    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
    1
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      DOI: 10.1016/j.celrep.2023.113307

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    sciencedirect.com/science/article/pii/S2211124723013190
  29. Oct 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113275

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    sciencedirect.com/science/article/pii/S2211124723012871
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury
    1
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      DOI: 10.4103/1673-5374.380907

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581548/
  32. Sep 2023
  33. www.sciencedirect.com www.sciencedirect.com
    The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells
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      DOI: 10.1016/j.ccell.2023.08.012

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    sciencedirect.com/science/article/abs/pii/S153561082300288X
  34. www.sciencedirect.com www.sciencedirect.com
    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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      DOI: 10.1016/j.isci.2023.107760

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    sciencedirect.com/science/article/pii/S2589004223018370
  35. www.cell.com www.cell.com
    Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation
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      DOI: 10.1016/j.celrep.2023.113079

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    cell.com/cell-reports/fulltext/S2211-1247(23)01090-2
  36. Jul 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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      DOI: 10.1016/j.xcrm.2023.101120

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    sciencedirect.com/science/article/pii/S2666379123002483
  38. dx.doi.org dx.doi.org
    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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      DOI: 10.1158/1535-7163.MCT-22-0224

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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
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      DOI: 10.1016/j.molcel.2023.06.007

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  40. 52.53.155.43 52.53.155.43
    mct-22-0224 (1)-html.html
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      DOI: 10.1158/1535-7163.mct-22-0224

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  41. Jun 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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      DOI: 10.1016/j.celrep.2023.112533

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    sciencedirect.com/science/article/pii/S2211124723005442
  43. May 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Round-window delivery of lithium chloride regenerates cochlear synapses damaged by noise-induced excitotoxic trauma via inhibition of the NMDA receptor in the rat
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      DOI: 10.1371/journal.pone.0284626

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    ncbi.nlm.nih.gov/pmc/articles/PMC10202264/
  45. www.tandfonline.com www.tandfonline.com
    Perturbation of mitochondrial dynamics links to the aggravation of periodontitis by diabetes
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      DOI: 10.1080/01478885.2023.2188705

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    tandfonline.com/doi/abs/10.1080/01478885.2023.2188705
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAP1 loss is associated with higher ASS1 expression in epithelioid mesothelioma: implications for therapeutic stratification.
    1
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      DOI: 10.1158/1541-7786.MCR-22-0635

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    ncbi.nlm.nih.gov/pmc/articles/PMC10150242/
  47. Apr 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
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      DOI: 10.1016/j.chom.2023.03.007

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    sciencedirect.com/science/article/pii/S1931312823001117
  49. www.embopress.org www.embopress.org
    Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability
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      DOI: 10.15252/emmm.202216775

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    embopress.org/doi/10.15252/emmm.202216775
  50. www.sciencedirect.com www.sciencedirect.com
    N-Terminomic Changes of Neurons During Excitotoxicity Reveal Proteolytic Events Associated with Synaptic Dysfunctions and Potential Targets for Neuroprotection
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      DOI: 10.1016/j.mcpro.2023.100543

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    sciencedirect.com/science/article/pii/S1535947623000531
  51. Mar 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Teneurin trans-axonal signaling prunes topographically missorted axons
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      DOI: 10.1016/j.celrep.2023.112192

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    sciencedirect.com/science/article/pii/S2211124723002036
  53. Dec 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SRSF6 balances mitochondrial-driven innate immune outcomes through alternative splicing of BAX
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      DOI: 10.7554/eLife.82244

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    ncbi.nlm.nih.gov/pmc/articles/PMC9718523/
  55. aacrjournals.org aacrjournals.org
    TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification
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      DOI: 10.1158/1541-7786.MCR-22-0231

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    aacrjournals.org/mcr/article/20/12/1763/711001/TFAP4-Activates-IGF2BP1-and-Promotes-Progression
  56. Nov 2022
  57. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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    A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
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  60. Oct 2022
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  62. journals.lww.com journals.lww.com
    Siponimod exerts neuroprotective effects on the retina and... : Neural Regeneration Research
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  63. Sep 2022
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    The human mitochondrial genome contains a second light strand promoter
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  65. Aug 2022
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    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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  68. Jul 2022
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    Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification
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  71. Jun 2022
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    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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  73. May 2022
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    The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling
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  76. Apr 2022
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    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
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    Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
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  79. Mar 2022
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    Insights From Long-term Follow-up of a Girl With Adrenal Insufficiency and Sphingosine-1-Phosphate Lyase Deficiency
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    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
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    The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells
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    Tumor-derived Jagged1 promotes cancer progression through immune evasion
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    Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1
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    Partial p53 reactivation is sufficient to induce cancer regression
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  86. Feb 2022
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    Identification and characterization of long non-coding RNA Carip in modulating spatial learning and memory
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    Disruption of amphetamine sensitization by alteration of dendritic thin spines in the nucleus accumbens core
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    Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes
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    Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal
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  91. Jan 2022
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    The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
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  93. Dec 2021
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    TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models
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  95. Nov 2021
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    Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs
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  97. Oct 2021
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    Role of Heat Shock Factor 1 in Conserving Cholesterol Transportation in Leydig Cell Steroidogenesis via Steroidogenic Acute Regulatory Protein
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  100. Sep 2021
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    Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion
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    GSTM1 and GSTT1 double null genotypes determining cell fate and proliferation as potential risk factors of relapse in children with hematological malignancies after hematopoietic stem cell transplantation
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  104. Aug 2021
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    Effect of handling on ATP utilization of cerebral Na,K-ATPase in rats with trimethyltin-induced neurodegeneration
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    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
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    Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms - Mar 20, 2017
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    Small molecule Photoregulin3 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa.
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    A Novel Retrieval-Dependent Memory Process Revealed by the Arrest of ERK1/2 Activation in the Basolateral Amygdala
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  111. Jul 2021
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    The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease
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  113. www.sciencedirect.com www.sciencedirect.com
    NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia
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      Mouse Anti-β-actin antibody

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  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Sulindac‐derived retinoid X receptor‐α modulator attenuates atherosclerotic plaque progression and destabilization in ApoE−/− mice
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      β‐actin

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    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
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  120. europepmc.org europepmc.org
    Small molecule Photoregulin3 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa.
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    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
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    Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation
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  124. Jun 2021
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    NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
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    Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy
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  127. May 2021
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
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  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Toll-like receptor 2 activation and up-regulation by high mobility group box-1 contribute to post-operative neuroinflammation and cognitive dysfunction in mice
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    Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance
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  131. Apr 2021
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    Principles of signaling pathway modulation for enhancing human naive pluripotency induction
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    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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  134. Mar 2021
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    Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels
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    Trigeminal Nerve Electrical Stimulation: An Effective Arousal Treatment for Loss of Consciousness
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  138. Feb 2021
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    Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot
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      DOI: 10.12688/f1000research.19803.2

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  140. Jan 2021
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  142. Nov 2020
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    Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG
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  144. Sep 2020
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    Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System
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    Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission
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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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    Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction
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    Srebf1 Controls Midbrain Dopaminergic Neurogenesis
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    Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α
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    A Genetic Toggle for Chemical Control of Individual Plk1 Substrates
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    A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development
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  153. rupress.org rupress.org
    GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508
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    Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism
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    Amyloid‐beta1‐42 induced glutamatergic receptor and transporter expression changes in the mouse hippocampus
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    Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot
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    CCB is involved in actin-based axonal transport of selected synaptic proteins
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    TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages
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    Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase
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  161. www.mdpi.com www.mdpi.com
    Toxicity of Carlina Oxide—A Natural Polyacetylene from the Carlina acaulis Roots—In Vitro and In Vivo Study
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    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
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  163. pubs.acs.org pubs.acs.org
    Proximal Biotinylation Based Combinatory Approach for Isolating Integral Plasma Membrane Proteins
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  164. Jan 2020
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    The Splicing Factor hnRNP M Is a Critical Regulator of Innate Immune Gene Expression in Macrophages
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    Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production
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    Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
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  168. journals.plos.org journals.plos.org
    Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice
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      DOI: 10.1371/journal.pone.0217819

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    RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis
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    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
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    A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors
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  172. f1000research.com f1000research.com
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  173. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
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  174. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glycogen metabolism is impaired in the brain of male type 2 diabetic Goto‐Kakizaki rats
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      DOI: 10.1002/jnr.24437

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    Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression
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    Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells
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  179. Nov 2018
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach
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    Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
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    Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment
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    Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy
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    A Novel Retrieval-Dependent Memory Process Revealed by the Arrest of ERK1/2 Activation in the Basolateral Amygdala
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    The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels
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    Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase
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    Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA
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    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
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  196. Nov 2017
  197. elifesciences.org elifesciences.org
    Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells
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    IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents
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    HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium
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    The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
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  201. journals.sagepub.com journals.sagepub.com
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  202. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prostaglandin E2 promotes neural proliferation and differentiation and regulates Wnt target gene expression
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23759/full
  203. www.jneurosci.org www.jneurosci.org
    Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates
    1
    1. scibot 08 Nov 2017
      AB_2223210

      Curator: @gabimpine

      Resource used:

      (Abcam Cat# ab6276, RRID:AB_2223210)

      SciCrunch record: RRID:AB_2223210

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2223210 RRIDCUR:Validated
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