380 Matching Annotations
  1. Sep 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Biomarker-related phospho-tau217 appears in synapses around Aβ plaques prior to tau tangle in cerebral cortex of preclinical Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S221112472500974X
  3. Aug 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiation of visualized exosomal miR-1306-3p from primary sensory neurons contributes to chronic visceral pain via spinal P2X3 receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363481/
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    Transcriptomic architecture of weak versus strong contextual fear extinction learning uncovers extinction-suppressive role of Tia1
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    sciencedirect.com/science/article/pii/S2667174325001454
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    GM1 Oligosaccharide Modulates Microglial Activation and α-Synuclein Clearance in a Human In Vitro Model
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    mdpi.com/1422-0067/26/15/7634
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    Microglia mediated by LAG3 regulate astrocyte morphogenesis in the brain white matter
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    sciencedirect.com/science/article/pii/S2211124725008836
  8. www.nature.com www.nature.com
    Gene editing for Spinocerebellar ataxia type 3 taking advantage of the human ATXN3L paralog as replacement gene
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    nature.com/articles/s41434-025-00557-2
  9. Jul 2025
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    The knockout of Moesin leads to excess microglia-mediated synaptic pruning and impairs social novelty in a mouse model
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    sciencedirect.com/science/article/pii/S2211124725007831
  11. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP287565
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    Deconstructing the intercellular interactome in vascular dementia with focal ischemia for therapeutic applications
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    cell.com/cell/fulltext/S0092-8674(25)00636-1
  13. Jun 2025
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    Heat-shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux
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    tandfonline.com/doi/abs/10.1080/15548627.2025.2466144
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    The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway
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    sciencedirect.com/science/article/pii/S1074761325002444
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    Meal scheduling corrects obesogenic diet induced-uncoupling of cortico-hippocampal activities supporting memory
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    sciencedirect.com/science/article/pii/S2352396425002270
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    Senescence-resistant human mesenchymal progenitor cells counter aging in primates
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    sciencedirect.com/science/article/pii/S0092867425005719
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    Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures
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    sciencedirect.com/science/article/pii/S2211124725005480
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    Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain
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    sciencedirect.com/science/article/pii/S0896627325003514
  20. May 2025
  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70081
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    Single-nucleus profiling of mouse inner ear aging uncovers cell type heterogeneity and hair cell subtype-specific age-related signatures
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    sciencedirect.com/science/article/pii/S2211124725005522
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12094574/
  24. link.springer.com link.springer.com
    Atorvastatin Protects Against the Macrophage/Microglia-Related Neuroinflammation via Inhibiting Lipocalin-2 in Mouse Experimental Intracerebral Hemorrhage Model
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    link.springer.com/article/10.1007/s10571-025-01566-w
  25. link.springer.com link.springer.com
    Astrocytic spermidine insufficiency contributes to enhanced pain sensitivity associated with ApoE4
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    link.springer.com/article/10.1186/s10194-025-02054-8
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic Vanadium Exposure Promotes Aggregation of Alpha‐Synuclein, Tau and Amyloid Beta in Mouse Brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12082766/
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    Impact of ATF6 deletion on the embryonic brain development
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  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017274/
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    CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density
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    Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease
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    Inflammasome signaling in astrocytes modulates hippocampal plasticity
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    Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia
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    sciencedirect.com/science/article/pii/S1074761325001694
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    Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
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    Optogenetic activation of cortical microglia promotes neuronal activity and pain hypersensitivity
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    sciencedirect.com/science/article/pii/S2211124725004887
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    A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy
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    sciencedirect.com/science/article/pii/S0045206825004316
  36. Apr 2025
  37. www.sciencedirect.com www.sciencedirect.com
    Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins
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    sciencedirect.com/science/article/pii/S1934590925000992
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    Pan-cancer human brain metastases atlas at single-cell resolution
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    sciencedirect.com/science/article/pii/S1535610825001266
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    A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions
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    Meningeal lymphatics-microglia axis regulates synaptic physiology
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  41. Mar 2025
  42. www.sciencedirect.com www.sciencedirect.com
    The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2
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  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of central and peripheral transient receptor potential melastatin 8 increases susceptibility to spreading depolarization and facilitates trigeminal neuroinflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11907788/
  44. journals.lww.com journals.lww.com
    The compound... : Neural Regeneration Research
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  45. Feb 2025
  46. www.nature.com www.nature.com
    PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors
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    nature.com/articles/s41593-024-01865-3
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11785056/
  48. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17475
  49. www.biorxiv.org www.biorxiv.org
    Microglial plasticity governed by state-specific enhancer landscapes
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    biorxiv.org/content/10.1101/2025.01.30.635595v1
  50. Jan 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of neuroinflammation by GIBH-130 (AD-16) reduces neurodegeneration, motor deficits, and proinflammatory cytokines in a hemiparkinsonian model
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    pmc.ncbi.nlm.nih.gov/articles/PMC11684390/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An atlas of neuropathic pain-associated molecular pathological characteristics in the mouse spinal cord
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    pmc.ncbi.nlm.nih.gov/articles/PMC11739467/
  53. Dec 2024
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the Synergistic Effects of Erinacines on Microglial Regulation and Alzheimer's Pathology Under Metabolic Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11652784/
  55. 52.53.155.43 52.53.155.43
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    Unraveling morphine tolerance: CCL2 induces spinal cord apoptosis via inhibition of Nrf2 signaling pathway and PGC-1α-mediated mitochondrial biogenesis
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    sciencedirect.com/science/article/pii/S0889159124007402
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    Protocol for handling and using SOD1 mice for amyotrophic lateral sclerosis pre-clinical studies
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    Effect of metabolic disorders on reactive gliosis and glial scarring at the early subacute phase of stroke in a mouse model of diabetes and obesity
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  60. www.sciencedirect.com www.sciencedirect.com
    Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S2211124724013330
  61. Nov 2024
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute exposure to diisopropylfluorophosphate in mice results in persistent cognitive deficits and alterations in senescence markers in the brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC11578986/
  63. www.sciencedirect.com www.sciencedirect.com
    Tak1 licenses mitochondrial transfer from astrocytes to POMC neurons to maintain glucose and cholesterol homeostasis
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  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imbalance in glucose metabolism regulates the transition of microglia from homeostasis to Disease Associated Microglia stage 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11097271/
  65. www.sciencedirect.com www.sciencedirect.com
    Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
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  66. www.sciencedirect.com www.sciencedirect.com
    Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer’s disease model
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    sciencedirect.com/science/article/pii/S1934590924003679
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11467935/
  68. Oct 2024
  69. link.springer.com link.springer.com
    Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow
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    link.springer.com/article/10.1038/s41467-024-52969-0
  70. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson’s disease
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    jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-024-03234-0
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    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
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  72. Sep 2024
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Immune Cells Promote BDNF Expression by Infiltrated Macrophages via Interleukin 4 in the Cerebral Ischemia of Male Rats
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    onlinelibrary.wiley.com/doi/10.1002/jnr.25379
  74. www.sciencedirect.com www.sciencedirect.com
    Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice
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    A cell type‐specific expression map of NCoR1 and SMRT transcriptional co‐repressors in the mouse brain
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    onlinelibrary.wiley.com/doi/10.1002/cne.24886
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    Metformin decelerates aging clock in male monkeys
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  77. Aug 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Switch to phagocytic microglia by CSFR1 inhibition drives amyloid-beta clearance from glutamatergic terminals rescuing LTP in acute hippocampal slices
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    ncbi.nlm.nih.gov/pmc/articles/PMC11344079/
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    Spliceosomal GTPase Eftud2 deficiency-triggered ferroptosis leads to Purkinje cell degeneration
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    A human fetal cerebellar map of the late second trimester reveals developmental molecular characteristics and abnormality in trisomy 21
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    Involvement of microglia in early axoglial alterations of the optic nerve induced by experimental glaucoma
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14070/full
  82. www.proquest.com www.proquest.com
    Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area - ProQuest
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    proquest.com/docview/2665142615
  83. www.ahajournals.org www.ahajournals.org
    Sphingomyelin Synthase 2 Inhibition Ameliorates Cerebral Ischemic Reperfusion Injury Through Reducing the Recruitment of Toll‐Like Receptor 4 to Lipid Rafts
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    ahajournals.org/doi/abs/10.1161/JAHA.119.012885
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    A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers
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    onlinelibrary.wiley.com/doi/10.1002/brb3.403/full
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    Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23672/full
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    Distribution of the creatine transporter throughout the human brain reveals a spectrum of creatine transporter immunoreactivity
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  87. www.nature.com www.nature.com
    Host circuit engagement of human cortical organoids transplanted in rodents
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    nature.com/articles/s41596-024-01029-4
  88. Jul 2024
  89. www.sciencedirect.com www.sciencedirect.com
    Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
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  90. www.cell.com www.cell.com
    Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy
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    cell.com/neuron/abstract/S0896-6273(24)00370-2
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampal astrocytes induce sex-dimorphic effects on memory
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  92. Jun 2024
  93. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Aquaporin-4 deletion leads to reduced infarct volume and increased peri-infarct astrocyte reactivity in a mouse model of cortical stroke
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP284099
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    Microglia protect against age-associated brain pathologies
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  95. www.sciencedirect.com www.sciencedirect.com
    TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
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    Neurodegeneration and glial morphological changes are both prevented by TRPM2 inhibition during the progression of a Parkinson's disease mouse model
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  97. link.springer.com link.springer.com
    Intrathecal Fumagillin Alleviates Chronic Neuropathy-Induced Nociceptive Sensitization and Modulates Spinal Astrocyte-Neuronal Glycolytic and Angiogenic Proteins
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    link.springer.com/article/10.1007/s12035-024-04254-w
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    DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis
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    link.springer.com/article/10.1007/s11064-024-04171-3
  99. May 2024
  100. www.sciencedirect.com www.sciencedirect.com
    An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination
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  203. Oct 2022
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    CSF1R-mediated myeloid cell depletion prolongs lifespan but aggravates distinct motor symptoms in a model of multiple system atrophy
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  210. Sep 2022
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    Synergistic effect of mild traumatic brain injury and alcohol aggravates neuroinflammation, amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations: Impact on psychological stress
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    Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex
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    Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas
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  218. Jul 2022
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    Intermittent theta burst stimulation ameliorates cognitive impairment and hippocampal gliosis in the Streptozotocin-induced model of Alzheimer's disease
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  227. May 2022
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    Regulation of perineuronal net components in the synaptic bouton vicinity on lumbar α-motoneurons in the rat after spinalization and locomotor training: New insights from spatio-temporal changes in gene, protein expression and WFA labeling
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  229. Apr 2022
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    Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain
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  232. Mar 2022
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    Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice
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    onlinelibrary.wiley.com/doi/10.1002/cne.24589
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    Periventricular microglial cells interact with dividing precursor cells in the nonhuman primate and rodent prenatal cerebral cortex
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    Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain
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    Melatonin prevents early pituitary dysfunction induced by sucrose-rich diets
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