37 Matching Annotations
  1. Nov 2026
  2. www.sciencedirect.com www.sciencedirect.com
    UFSP2 constitutes a targetable vulnerability via deUFMylation-dependent activation of AKT oncogenic signaling
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    sciencedirect.com/science/article/pii/S2211124726012933
  3. Feb 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leveraging menstrual effluent (ME) to investigate vitamin D and human decidualization, a potential link with fertility
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    pmc.ncbi.nlm.nih.gov/articles/PMC12933435/
  5. 54.241.53.176 54.241.53.176
    2026.02.11.705361v1.full-html.html
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    54.241.53.176/5c618bd82011554652ee37be2d6b5f0590a656fa/2026.02.11.705361v1.full-html.html
  6. Jan 2026
  7. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target
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    sciencedirect.com/science/article/pii/S2666379125006512
  8. Nov 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTEN Oxidation Promotes Constitutive PI3K Signaling and Inducible Macropinocytosis in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12614194/
  10. Oct 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Plectin by Akt3 Promotes Triple-Negative Breast Cancer Cell Invasive Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508894/
  12. Sep 2025
  13. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225018139-main-html.html
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    52.53.155.43/253550384e171aeac03650972660e6e19e7d73f6/1-s2.0-S2589004225018139-main-html.html
  14. Feb 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases
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    pmc.ncbi.nlm.nih.gov/articles/PMC11866499/
  16. Dec 2024
  17. www.sciencedirect.com www.sciencedirect.com
    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
  18. Nov 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High fat diet induced hepatic insulin resistance per se attenuates murine de novo lipogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11550620/
  20. Aug 2024
  21. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
  23. Jul 2024
  24. www.science.org www.science.org
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    science.org/doi/10.1126/science.adk0775
  25. Jan 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
  27. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    sciencedirect.com/science/article/pii/S0021925824000176
  28. May 2023
  29. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    sciencedirect.com/science/article/pii/S2211124723005478
  30. Apr 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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    sciencedirect.com/science/article/pii/S2211124722004223
  32. Mar 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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    sciencedirect.com/science/article/pii/S2211124722002455
  34. Dec 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Translational and post-translational control of human naïve versus primed pluripotency
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    sciencedirect.com/science/article/pii/S2589004221016151
  36. Nov 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit the sensitivity to PI3Kα inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8137641/
  38. Aug 2021
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5589416/
  40. Jul 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6363423/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
  43. Oct 2020
  44. www.sciencedirect.com www.sciencedirect.com
    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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    sciencedirect.com/science/article/pii/S2211124720312122
  45. www.sciencedirect.com www.sciencedirect.com
    The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
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    sciencedirect.com/science/article/pii/S2211124720312195
  46. Sep 2020
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA‐mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14979
  48. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
  49. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902305R
  50. www.sciencedirect.com www.sciencedirect.com
    Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
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    sciencedirect.com/science/article/pii/S2211124720307609
  51. www.sciencedirect.com www.sciencedirect.com
    Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition
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    sciencedirect.com/science/article/pii/S2211124720301054
  52. Jan 2020
  53. www.sciencedirect.com www.sciencedirect.com
    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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    sciencedirect.com/science/article/pii/S1097276519305532
  54. www.sciencedirect.com www.sciencedirect.com
    Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling
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    sciencedirect.com/science/article/pii/S2451945619303964
  55. www.sciencedirect.com www.sciencedirect.com
    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
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    sciencedirect.com/science/article/pii/S2211124719312355
  56. www.sciencedirect.com www.sciencedirect.com
    Individual Cells Can Resolve Variations in Stimulus Intensity along the IGF-PI3K-AKT Signaling Axis
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    sciencedirect.com/science/article/pii/S2405471219303916
  57. Nov 2018
  58. www.sciencedirect.com www.sciencedirect.com
    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
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    sciencedirect.com/science/article/pii/S155041311830514X
  59. Nov 2017
  60. elifesciences.org elifesciences.org
    Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system
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    elifesciences.org/articles/29241