90 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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    1. scibot 19 Apr 2024
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      DOI: 10.1038/s44318-024-00065-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.bbadis.2024.167131

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    sciencedirect.com/science/article/pii/S0925443924001200
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    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy
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      DOI: 10.1016/j.xcrm.2024.101461

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    sciencedirect.com/science/article/pii/S2666379124001058
  6. Feb 2024
  7. 52.53.155.43 52.53.155.43
    A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
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    1. scibot 29 Feb 2024
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      DOI: 10.1101/2023.10.24.563545

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      DOI: 10.1101/2023.10.24.563545

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    52.53.155.43/208912a7429960b4182882fc2fcf60d73a185bc4/delete-html.html
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    Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer
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    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.molmet.2024.101900

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    sciencedirect.com/science/article/pii/S2212877824000310
  9. Jan 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Augmentation of scleral glycolysis promotes myopia through histone lactylation
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.023

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    sciencedirect.com/science/article/pii/S1550413123004746
  11. Nov 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113424

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    sciencedirect.com/science/article/pii/S2211124723014365
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    Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
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    1. scibot 22 Nov 2023
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      DOI: 10.1016/j.cmet.2023.10.017

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      DOI: 10.1016/j.cmet.2023.10.017

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    sciencedirect.com/science/article/pii/S1550413123003868
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS
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    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
  15. Oct 2023
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    MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
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    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723012330
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
    1
    1. scibot 12 Oct 2023
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      DOI: 10.3892/ol.2023.14067

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561147/
  18. Sep 2023
  19. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    1. scibot 22 Sep 2023
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      DOI: 10.1038/s41422-023-00874-4

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    nature.com/articles/s41422-023-00874-4
  20. dx.doi.org dx.doi.org
    Insulin Signaling Is Preserved in Skeletal Muscle During Early Diabetic Ketoacidosis
    1
    1. scibot 14 Sep 2023
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      DOI: 10.1210/clinem/dgad464

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    dx.doi.org/10.1210/clinem/dgad464
  21. Jul 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
    1
    1. scibot 22 Jul 2023
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      DOI: 10.1016/j.cmet.2023.06.013

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    sciencedirect.com/science/article/pii/S1550413123002231
  23. Jun 2023
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    Acetate controls endothelial-to-mesenchymal transition
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cmet.2023.05.010

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    sciencedirect.com/science/article/pii/S1550413123002036
  25. May 2023
  26. link.springer.com link.springer.com
    Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity
    1
    1. scibot 18 May 2023
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      DOI: 10.1038/s41598-023-33924-3

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    link.springer.com/article/10.1038/s41598-023-33924-3
  27. Mar 2023
  28. www.ijbs.com www.ijbs.com
    IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins
    1
    1. scibot 30 Mar 2023
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      DOI: 10.7150/ijbs.78248

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    ijbs.com/v19p1490.htm
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Experimental evidence and clinical implications of Warburg effect in the skeletal muscle of Fabry disease
    1
    1. scibot 09 Mar 2023
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      DOI: 10.1016/j.isci.2023.106074

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    ncbi.nlm.nih.gov/pmc/articles/PMC9984560/
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
    1
    1. scibot 25 Feb 2023
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      DOI: 10.1016/j.cmet.2023.01.012

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    sciencedirect.com/science/article/pii/S1550413123000128
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
    1
    1. scibot 15 Feb 2023
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      DOI: 10.7554/eLife.86471

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910825/
  33. www.sciencedirect.com www.sciencedirect.com
    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
    1
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      DOI: 10.1016/j.celrep.2023.112033

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    sciencedirect.com/science/article/pii/S221112472300044X
  34. Jan 2023
  35. www.nature.com www.nature.com
    Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3
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      DOI: 10.1038/s41598-023-28576-2

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    nature.com/articles/s41598-023-28576-2
  36. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions
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    1. scibot 10 Jan 2023
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      DOI: 10.1016/j.isci.2022.105811

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    sciencedirect.com/science/article/pii/S2589004222020843
  37. Nov 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
    1
    1. scibot 19 Nov 2022
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      DOI: 10.1158/2767-9764.crc-22-0256

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648418/
  39. Jun 2022
  40. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
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    1. scibot 30 Jun 2022
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      DOI: 10.1158/2159-8290.CD-21-1022

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      DOI: 10.1158/2159-8290.cd-21-1022

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      DOI: 10.1158/2159-8290.cd-21-1022

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    52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
  41. www.sciencedirect.com www.sciencedirect.com
    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
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    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.isci.2022.104447

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    sciencedirect.com/science/article/pii/S2589004222007180
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
    1
    1. scibot 01 Jun 2022
      RRID:AB_2232946

      DOI: 10.3389/fphar.2022.848957

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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
  43. May 2022
  44. www.sciencedirect.com www.sciencedirect.com
    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
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      DOI: 10.1016/j.devcel.2022.04.020

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    sciencedirect.com/science/article/pii/S1534580722003069
  45. Apr 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 1 cellular localization regulates the metabolic fate of glucose
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      DOI: 10.1016/j.molcel.2022.02.028

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    sciencedirect.com/science/article/pii/S1097276522001666
  47. Mar 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch
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      DOI: 10.1016/j.celrep.2022.110468

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    sciencedirect.com/science/article/pii/S2211124722002017
  49. Dec 2021
  50. www.nature.com www.nature.com
    GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure
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      DOI: 10.1038/s41419-021-04394-0

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    nature.com/articles/s41419-021-04394-0
  51. Oct 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differences in Glycolysis and Mitochondrial Respiration between Cytotrophoblast and Syncytiotrophoblast In-Vitro: Evidence for Sexual Dimorphism
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      DOI: 10.3390/ijms221910875

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    ncbi.nlm.nih.gov/pmc/articles/PMC8509198/
  53. www.sciencedirect.com www.sciencedirect.com
    PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes
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      DOI: 10.1016/j.celrep.2021.109767

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    sciencedirect.com/science/article/pii/S2211124721012213
  54. Aug 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE
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      DOI: 10.1016/j.cell.2021.07.021

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    sciencedirect.com/science/article/pii/S0092867421008801
  56. www.sciencedirect.com www.sciencedirect.com
    Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells
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      DOI: 10.1016/j.cmet.2021.07.015

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    sciencedirect.com/science/article/pii/S1550413121003314
  57. Jul 2021
  58. academic.oup.com academic.oup.com
    Untitled document
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      DOI: 10.1210/en.2018-00887

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    academic.oup.com/endo/article/160/2/313/5224519
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    Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
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      DOI: 10.1016/j.cell.2019.11.016

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  60. Jun 2021
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    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
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  62. May 2021
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    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity
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    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
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    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells
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  66. Apr 2021
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    Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
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    Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer
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    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
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  70. Feb 2021
  71. journals.physiology.org journals.physiology.org
    Cardiac expression and location of hexokinase changes in a mouse model of pure creatine-deficiency
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    Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training
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    Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses
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    Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency | American Journal of Physiology-Heart and Circulatory Physiology
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    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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    Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation
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    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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  78. Jan 2021
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    ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism
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  80. Nov 2020
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    Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity
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  82. Oct 2020
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    Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
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  84. Sep 2020
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    Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer
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    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
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    Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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    HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer
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    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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  92. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
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  94. Jan 2020
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    Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
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    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
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    Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
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    Hepatic HKDC1 Expression Contributes to Liver Metabolism
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    Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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    Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers
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    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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    Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism
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  105. Nov 2018
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species
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    Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients
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    The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
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    Transcriptional Regulation of the Warburg Effect in Cancer by SIX1
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  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hexokinase 2‐dependent Hyperglycolysis Driving Microglial Activation Contributes to Ischemic Brain Injury
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses
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    HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium
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    Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake
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