112 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
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    1. scibot 30 Apr 2024
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      DOI: 10.1101/2024.04.02.587836

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    1. scibot 13 Apr 2024
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      DOI: 10.1128/mbio.00299-24

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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
  4. Mar 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis
    1
    1. scibot 23 Mar 2024
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      DOI: 10.1002/pro.4949

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    ncbi.nlm.nih.gov/pmc/articles/PMC10955614/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1158/1535-7163.MCT-23-0025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  7. www.sciencedirect.com www.sciencedirect.com
    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113875

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    2. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113875

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    sciencedirect.com/science/article/pii/S2211124724002031
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    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
    3
    1. scibot 01 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.004

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    2. scibot 01 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.004

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    3. scibot 01 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.004

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    sciencedirect.com/science/article/pii/S1535610824000485
  9. Feb 2024
  10. link.springer.com link.springer.com
    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1186/s12935-024-03231-6

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    link.springer.com/article/10.1186/s12935-024-03231-6
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosomes derived from bladder epithelial cells infected with uropathogenic Escherichia coli increase the severity of urinary tract infections (UTIs) by impairing macrophage function
    1
    1. scibot 01 Feb 2024
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      DOI: 10.1371/journal.ppat.1011926

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798623/
  12. Jan 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 26 Jan 2024
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      DOI: 10.1101/2023.05.04.539399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  14. www.sciencedirect.com www.sciencedirect.com
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
    1
    1. scibot 23 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.032

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    sciencedirect.com/science/article/pii/S0092867423014381
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.003

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    sciencedirect.com/science/article/pii/S1097276523010225
  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
    1
    1. scibot 06 Dec 2023
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      DOI: 10.1016/j.isci.2023.108405

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    ncbi.nlm.nih.gov/pmc/articles/PMC10692727/
  18. Sep 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    1. scibot 16 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113098

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    sciencedirect.com/science/article/pii/S2211124723011099
  20. Aug 2023
  21. 52.53.155.43 52.53.155.43
    Type 2 cytokines promote angiogenesis in ischemic muscle via endothelial IL-4Rα signaling
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112964

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112964

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    52.53.155.43/140adeeb58a1ff7d16285ad7e38b3ece92d908b2/PIIS2211124723009750-html.html
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.isci.2023.107368

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    ncbi.nlm.nih.gov/pmc/articles/PMC10407955/
  23. 52.53.155.43 52.53.155.43
    mct-23-0025 (1)-html.html
    1
    1. scibot 11 Aug 2023
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      DOI: 10.1158/1535-7163.mct-23-0025

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    52.53.155.43/1629e82c15a2ef751662f24158b1c1b52e5a2112/mct-23-0025 (1)-html.html
  24. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
    1
    1. scibot 04 Aug 2023
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      DOI: 10.1016/j.ccell.2023.07.005

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    sciencedirect.com/science/article/pii/S1535610823002453
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
    1. scibot 01 Aug 2023
      RRID:AB_2233307

      DOI: 10.3390/ijms241411821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  26. Jul 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
    1
    1. scibot 15 Jul 2023
      RRID:AB_2233307

      DOI: 10.1016/j.celrep.2023.112798

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    sciencedirect.com/science/article/pii/S2211124723008094
  28. www.nature.com www.nature.com
    Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1038/s41467-023-39715-8

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    nature.com/articles/s41467-023-39715-8
  29. www.sciencedirect.com www.sciencedirect.com
    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
    1
    1. scibot 12 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112746

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    sciencedirect.com/science/article/pii/S221112472300757X
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Nutrient-dependent regulation of β-cell proinsulin content
    1
    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.jbc.2023.104836

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    sciencedirect.com/science/article/pii/S0021925823018641
  32. www.sciencedirect.com www.sciencedirect.com
    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
    1
    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112579

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    sciencedirect.com/science/article/pii/S2211124723005909
  33. May 2023
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
    1
    1. scibot 04 May 2023
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      DOI: 10.1158/0008-5472.CAN-22-3000

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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  36. Apr 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
    1
    1. scibot 25 Apr 2023
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      DOI: 10.1016/j.isci.2023.106552

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    sciencedirect.com/science/article/pii/S2589004223006296
  38. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  39. www.sciencedirect.com www.sciencedirect.com
    Adipocyte-derived chemerin rescues lipid overload-induced cardiac dysfunction
    1
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      DOI: 10.1016/j.isci.2023.106495

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    sciencedirect.com/science/article/pii/S2589004223005722
  40. Mar 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
    1
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      DOI: 10.1016/j.isci.2023.106293

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    ncbi.nlm.nih.gov/pmc/articles/PMC10025096/
  42. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823000326
  43. Feb 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
    1
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      DOI: 10.3233/ADR-220056

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    ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
  45. Jan 2023
  46. www.sciencedirect.com www.sciencedirect.com
    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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      DOI: 10.1016/j.celrep.2023.112037

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    sciencedirect.com/science/article/pii/S2211124723000487
  47. Dec 2022
  48. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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      DOI: 10.15252/embj.2022111961

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      DOI: 10.15252/embj.2022111961

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    embopress.org/doi/10.15252/embj.2022111961
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells
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      DOI: 10.1016/j.isci.2022.105747

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    ncbi.nlm.nih.gov/pmc/articles/PMC9794981/
  50. www.sciencedirect.com www.sciencedirect.com
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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      DOI: 10.1016/j.ccell.2022.11.015

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    sciencedirect.com/science/article/pii/S1535610822005621
  51. Sep 2022
  52. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
    1
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      DOI: 10.1016/j.celrep.2022.111428

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    sciencedirect.com/science/article/pii/S2211124722012694
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
    1
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  69. Jan 2022
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    Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II - Md Al Rahim, Shabarish Thatipamula, Giulio M. Pasinetti, Mir Ahamed Hossain, 2021
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4
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  115. Jan 2020
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    TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion
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    CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
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    Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension
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    Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis
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  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co‐chaperone STI1
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  122. elifesciences.org elifesciences.org
    The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders
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    Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma
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    Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
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  125. elifesciences.org elifesciences.org
    Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
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    A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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  133. Nov 2018
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    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
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    Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53
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  140. Nov 2017
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    A Cell-Autonomous Mammalian 12 hr Clock Coordinates Metabolic and Stress Rhythms
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    PPARδ Promotes Running Endurance by Preserving Glucose
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    An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2
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