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    mRNA-delivery of IDO1 suppresses T cell-mediated autoimmunity
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    sciencedirect.com/science/article/pii/S2666379124004385
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    sciencedirect.com/science/article/pii/S0092867424009048
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
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  5. Aug 2024
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    Non-canonical metabolic and molecular effects of calorie restriction are revealed by varying temporal conditions
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    sciencedirect.com/science/article/pii/S2211124724010143
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    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
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  8. Jul 2024
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    Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
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  10. May 2024
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    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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  12. Apr 2024
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    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
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    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
  15. Mar 2024
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    Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10955614/
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    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
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    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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  20. Feb 2024
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    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
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    Exosomes derived from bladder epithelial cells infected with uropathogenic Escherichia coli increase the severity of urinary tract infections (UTIs) by impairing macrophage function
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  23. Jan 2024
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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  27. Dec 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
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  29. Sep 2023
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    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
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  31. Aug 2023
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    Type 2 cytokines promote angiogenesis in ischemic muscle via endothelial IL-4Rα signaling
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    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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    mct-23-0025 (1)-html.html
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
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  37. Jul 2023
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    Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
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    Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
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    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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  41. Jun 2023
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    Nutrient-dependent regulation of β-cell proinsulin content
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    sciencedirect.com/science/article/pii/S0021925823018641
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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    sciencedirect.com/science/article/pii/S2211124723005909
  44. May 2023
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    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
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    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  47. Apr 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
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    sciencedirect.com/science/article/pii/S2589004223006296
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    sciencedirect.com/science/article/pii/S2211124723002206
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    Adipocyte-derived chemerin rescues lipid overload-induced cardiac dysfunction
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    sciencedirect.com/science/article/pii/S2589004223005722
  51. Mar 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10025096/
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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  54. Feb 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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  56. Jan 2023
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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  58. Dec 2022
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    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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    N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells
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    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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  62. Sep 2022
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    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma
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    Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
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  67. Aug 2022
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    Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia
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  69. Jun 2022
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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    ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity
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  72. May 2022
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    Protocol to induce and assess cGAS-STING pathway activation in vitro
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  74. Apr 2022
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    Functional elements of the cis-regulatory lincRNA-p21
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    In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1
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  77. Mar 2022
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    Mucus sialylation determines intestinal host-commensal homeostasis
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    Gold(I)-Catalyzed Intramolecular Hydrothiophenylation of N-Thiophen-3-yl Alkynylamides for Accessing Thieno[3,2-b]pyridine-5(4H)-ones: Development of F-Actin Specific Fluorescent Probes
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  80. Jan 2022
  81. elifesciences.org elifesciences.org
    Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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  83. Dec 2021
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    The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
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    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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  86. Oct 2021
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    Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
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  88. Sep 2021
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    Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
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  90. Aug 2021
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  94. Jul 2021
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    BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association
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  96. Jun 2021
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    Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II - Md Al Rahim, Shabarish Thatipamula, Giulio M. Pasinetti, Mir Ahamed Hossain, 2021
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    Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library
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  99. May 2021
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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  101. Apr 2021
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    The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
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  103. Feb 2021
  104. www.cell.com www.cell.com
    Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation
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    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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    Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype
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  107. Jan 2021
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    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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    Isolation and characterization of extracellular vesicles produced by cell lines
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  110. Dec 2020
  111. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel HDAC6 inhibitor improves myelination of Schwann cells in a model of Charcot‐Marie‐Tooth disease type 1A
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  112. Nov 2020
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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    Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4
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    Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
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    Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
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    A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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  144. Nov 2018
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    An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer
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