125 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
    1
    1. scibot 08 Nov 2024
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      DOI: 10.1158/0008-5472.CAN-23-3574

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532783/
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Geranylgeranylated SCFFBXO10 regulates selective outer mitochondrial membrane proteostasis and function
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114783

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    sciencedirect.com/science/article/pii/S2211124724011343
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114606

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    ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
  6. www.sciencedirect.com www.sciencedirect.com
    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S1535610824003179
  7. elifesciences.org elifesciences.org
    SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
    1
    1. scibot 25 Sep 2024
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      DOI: 10.7554/eLife.25158

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    elifesciences.org/content/6/e25158
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
    1
    1. scibot 12 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010726
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    mRNA-delivery of IDO1 suppresses T cell-mediated autoimmunity
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004385
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009048
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    Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation
    1
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    sciencedirect.com/science/article/pii/S2666379124004324
  12. Aug 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Non-canonical metabolic and molecular effects of calorie restriction are revealed by varying temporal conditions
    1
    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724010143
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    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
    1
    1. scibot 18 Aug 2024
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    sciencedirect.com/science/article/pii/S266637912400377X
  15. Jul 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
    1
    1. scibot 31 Jul 2024
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    sciencedirect.com/science/article/pii/S1550413124002766
  17. May 2024
  18. journals.asm.org journals.asm.org
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
    1
    1. scibot 24 May 2024
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      DOI: 10.1128/mbio.00299-24

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    journals.asm.org/doi/10.1128/mbio.00299-24
  19. Apr 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1101/2024.04.02.587836

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
    1
    1. scibot 13 Apr 2024
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      DOI: 10.1128/mbio.00299-24

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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
  22. Mar 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis
    1
    1. scibot 23 Mar 2024
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      DOI: 10.1002/pro.4949

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    ncbi.nlm.nih.gov/pmc/articles/PMC10955614/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1158/1535-7163.MCT-23-0025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  25. www.sciencedirect.com www.sciencedirect.com
    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
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      DOI: 10.1016/j.celrep.2024.113875

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    sciencedirect.com/science/article/pii/S2211124724002031
  26. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
    3
    1. scibot 01 Mar 2024
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    2. scibot 01 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.004

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    3. scibot 01 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.004

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    sciencedirect.com/science/article/pii/S1535610824000485
  27. Feb 2024
  28. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
    1
    1. scibot 07 Feb 2024
      RRID:AB_2233307

      DOI: 10.1186/s12935-024-03231-6

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    cancerci.biomedcentral.com/articles/10.1186/s12935-024-03231-6
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosomes derived from bladder epithelial cells infected with uropathogenic Escherichia coli increase the severity of urinary tract infections (UTIs) by impairing macrophage function
    1
    1. scibot 01 Feb 2024
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      DOI: 10.1371/journal.ppat.1011926

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798623/
  30. Jan 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    1. scibot 26 Jan 2024
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      DOI: 10.1101/2023.05.04.539399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  32. www.sciencedirect.com www.sciencedirect.com
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
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    1. scibot 23 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.032

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    sciencedirect.com/science/article/pii/S0092867423014381
  33. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.003

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    sciencedirect.com/science/article/pii/S1097276523010225
  34. Dec 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
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    1. scibot 06 Dec 2023
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      DOI: 10.1016/j.isci.2023.108405

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    ncbi.nlm.nih.gov/pmc/articles/PMC10692727/
  36. Sep 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    1. scibot 16 Sep 2023
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    sciencedirect.com/science/article/pii/S2211124723011099
  38. Aug 2023
  39. 52.53.155.43 52.53.155.43
    Type 2 cytokines promote angiogenesis in ischemic muscle via endothelial IL-4Rα signaling
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    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112964

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    52.53.155.43/140adeeb58a1ff7d16285ad7e38b3ece92d908b2/PIIS2211124723009750-html.html
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10407955/
  41. 52.53.155.43 52.53.155.43
    mct-23-0025 (1)-html.html
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610823002453
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
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      DOI: 10.3390/ijms241411821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  44. Jul 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2211124723008094
  46. www.nature.com www.nature.com
    Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
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      DOI: 10.1038/s41467-023-39715-8

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    nature.com/articles/s41467-023-39715-8
  47. www.sciencedirect.com www.sciencedirect.com
    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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    sciencedirect.com/science/article/pii/S221112472300757X
  48. Jun 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Nutrient-dependent regulation of β-cell proinsulin content
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      DOI: 10.1016/j.jbc.2023.104836

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    sciencedirect.com/science/article/pii/S0021925823018641
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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      DOI: 10.1016/j.celrep.2023.112579

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    sciencedirect.com/science/article/pii/S2211124723005909
  51. May 2023
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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    1. scibot 05 May 2023
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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  54. Apr 2023
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    Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
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  58. Mar 2023
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  61. Feb 2023
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    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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  63. Jan 2023
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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    Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma
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    Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
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  74. Aug 2022
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    Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia
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  76. Jun 2022
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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  79. May 2022
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  81. Apr 2022
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    Functional elements of the cis-regulatory lincRNA-p21
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  84. Mar 2022
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    Gold(I)-Catalyzed Intramolecular Hydrothiophenylation of N-Thiophen-3-yl Alkynylamides for Accessing Thieno[3,2-b]pyridine-5(4H)-ones: Development of F-Actin Specific Fluorescent Probes
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  87. Jan 2022
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    Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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  90. Dec 2021
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    The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
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    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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  93. Oct 2021
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  95. Sep 2021
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  97. Aug 2021
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  101. Jul 2021
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  103. Jun 2021
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    Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II - Md Al Rahim, Shabarish Thatipamula, Giulio M. Pasinetti, Mir Ahamed Hossain, 2021
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    Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library
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  106. May 2021
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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  108. Apr 2021
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    The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
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  110. Feb 2021
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    Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation
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    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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      SciCrunch record: RRID:AB_2233307

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2233307 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117302905
  160. www.sciencedirect.com www.sciencedirect.com
    PPARδ Promotes Running Endurance by Preserving Glucose
    1
    1. scibot 08 Nov 2017
      AB_2233307

      Curator: @gabimpine

      Resource used:

      (Cell Signaling Technology Cat# 4877S, RRID:AB_2233307)

      SciCrunch record: RRID:AB_2233307

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2233307 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117302115
  161. www.sciencedirect.com www.sciencedirect.com
    An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer
    1
    1. scibot 08 Nov 2017
      Rabbit monoclonal anti-HSP90 (C45G5)

      Curator: @chewbeccax

      Resource used:

      (Cell Signaling Technology Cat# 4877S, RRID:AB_2233307)

      SciCrunch record: RRID:AB_2233307

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2233307 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416316671
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2
    2
    1. scibot 08 Nov 2017
      AB_2233307

      Curator: @Zeljana_Babic

      Resource used:

      (Cell Signaling Technology Cat# 4877S, RRID:AB_2233307)

      SciCrunch record: RRID:AB_2233307

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2233307 RRIDCUR:Validated
    2. scibot 08 Nov 2017
      AB_2233307

      Curator: @gabimpine

      Resource used:

      (Cell Signaling Technology Cat# 4877S, RRID:AB_2233307)

      SciCrunch record: RRID:AB_2233307

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2233307 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5241118/