Hypothesis

15 Matching Annotations

May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1186/s40478-025-02000-4
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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RRID:AB_223453

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy

2
1. scibot 21 Mar 2024
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2024.02.017
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
2. scibot 21 Mar 2024
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2024.02.017
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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RRID:AB_223453

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scibot

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sciencedirect.com/science/article/pii/S0896627324001272
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo

1
1. scibot 12 Jan 2024
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.3389/fnmol.2023.1320182
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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RRID:AB_223453

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC10773814/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2023.10.023
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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scibot

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sciencedirect.com/science/article/pii/S0896627323008048
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Super-resolution imaging unveils the self-replication of tau aggregates upon seeding

1
1. scibot 05 Jul 2023
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.celrep.2023.112725
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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RRID:AB_223453

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scibot

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sciencedirect.com/science/article/pii/S2211124723007362
Jun 2023
www.sciencedirect.com www.sciencedirect.com

An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

1
1. scibot 23 Jun 2023
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2023.05.006
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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scibot

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sciencedirect.com/science/article/pii/S0896627323003793
Nov 2022
www.sciencedirect.com www.sciencedirect.com

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

1
1. scibot 11 Nov 2022
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2022.10.022
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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RRID:AB_223453

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scibot

URL

sciencedirect.com/science/article/pii/S0896627322009552
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Hydroxychloroquine inhibits the mitochondrial antioxidant system in activated T cells

1
1. scibot 08 Dec 2021
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.isci.2021.103509
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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scibot

URL

sciencedirect.com/science/article/pii/S2589004221014802
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Repetitive Diffuse Mild Traumatic Brain Injury Causes an Atypical Astrocyte Response and Spontaneous Recurrent Seizures

1
1. scibot 28 Jul 2021
  
  in Public
  
  AB_223453
  
  DOI: 10.1523/JNEUROSCI.1067-18.2018
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453 RRIDCUR:Unrecognized
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RRIDCUR:Unrecognized

RRID:AB_223453

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6407295/
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms

1
1. scibot 22 Jun 2021
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2021.05.034
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453
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RRID:AB_223453

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scibot

URL

sciencedirect.com/science/article/pii/S089662732100413X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

1
1. scibot 09 Apr 2021
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1016/j.neuron.2021.03.024
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223453
  
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  RRIDCUR:Validated RRID:AB_223453
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RRID:AB_223453

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S089662732100194X
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1038/s41598-020-60777-x
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_223453
  
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  RRID:AB_223453 RRIDCUR:Validated
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RRID:AB_223453

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7052165/
link.springer.com link.springer.com

Tau reduction in aged mice does not impact Microangiopathy

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:AB_223453
  
  DOI: 10.1186/s40478-020-01014-4
  
  Resource: (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223453
  
  What is this?
  
  RRID:AB_223453 RRIDCUR:Validated
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RRID:AB_223453

RRIDCUR:Validated

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scibot

URL

link.springer.com/article/10.1186/s40478-020-01014-4
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy

1
1. scibot 05 Nov 2018
  
  in Public
  
  ThermoFisher Scientific#MN1000B
  
  Curator: @bandrow
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# MN1000B, RRID:AB_223453)
  
  SciCrunch record: RRID:AB_223453
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_223453 RRIDCUR:Missing
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RRID:AB_223453

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2213231717306687