40 Matching Annotations
  1. May 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1074761325001815
  3. Mar 2025
  4. www.sciencedirect.com www.sciencedirect.com
    PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy
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    sciencedirect.com/science/article/pii/S1535610825000765
  5. Jan 2025
  6. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Roles of blood monocytes carrying TREM2R47H mutation in pathogenesis of Alzheimer's disease and its therapeutic potential in APP/PS1 mice
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    alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.14402
  7. Dec 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
  9. Sep 2024
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impaired cellular copper regulation in the presence of ApoE4
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16198
  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
  13. Jul 2024
  14. www.sciencedirect.com www.sciencedirect.com
    PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms
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    sciencedirect.com/science/article/pii/S2211124724008568
  15. www.sciencedirect.com www.sciencedirect.com
    Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
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    sciencedirect.com/science/article/pii/S155041312400192X
  16. May 2024
  17. www.mdpi.com www.mdpi.com
    Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function
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    mdpi.com/1422-0067/25/10/5417
  18. Dec 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  20. Aug 2023
  21. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
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    52.53.155.43/ea1e2390c2d37ea00d2075acaef6f5d93e41dc17/can-23-1252-html.html
  22. Jul 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
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    sciencedirect.com/science/article/pii/S2666379123002574
  24. Jun 2023
  25. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16065
  26. May 2023
  27. www.mdpi.com www.mdpi.com
    Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function
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    mdpi.com/2073-4409/10/2/413/htm
  28. Dec 2022
  29. link.springer.com link.springer.com
    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    link.springer.com/article/10.1007/s12035-022-03153-2
  30. May 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Cholesterol determines the cytosolic entry and seeded aggregation of tau
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    sciencedirect.com/science/article/pii/S221112472200540X
  32. Apr 2022
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibiting α1-adrenergic receptor signaling pathway ameliorates AD-type pathologies and behavioral deficits in APPswe/PS1 mouse model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15603
  34. Mar 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat
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    sciencedirect.com/science/article/pii/S2211124722003102
  36. www.sciencedirect.com www.sciencedirect.com
    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
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    sciencedirect.com/science/article/pii/S2211124722001474
  37. Jan 2022
  38. www.embopress.org www.embopress.org
    Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance
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    embopress.org/doi/full/10.15252/embr.202153373
  39. Nov 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
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    sciencedirect.com/science/article/pii/S0896627321008667
  41. Oct 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
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    sciencedirect.com/science/article/pii/S1534580721007334
  43. Aug 2021
  44. www.nature.com www.nature.com
    Untitled document
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    nature.com/articles/s41598-019-39494-7
  45. Jul 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer’s Disease Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC6028735/
  47. Apr 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
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    sciencedirect.com/science/article/pii/S1550413120305532
  49. Feb 2021
  50. link.springer.com link.springer.com
    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
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    link.springer.com/article/10.1186/s13024-020-00366-8
  51. Jan 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse
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    ncbi.nlm.nih.gov/pmc/articles/PMC7842215/
  53. Dec 2020
  54. www.sciencedirect.com www.sciencedirect.com
    Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy
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    sciencedirect.com/science/article/pii/S2352396420305326
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Is a Negative Regulator of Oligodendrocyte Progenitor Cell Differentiation in the Adult Mouse Brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC7691426/
  56. Oct 2020
  57. www.sciencedirect.com www.sciencedirect.com
    PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer
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    sciencedirect.com/science/article/pii/S2211124720312420
  58. Sep 2020
  59. link.springer.com link.springer.com
    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
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    link.springer.com/article/10.1186/s13024-020-00366-8
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures
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    onlinelibrary.wiley.com/doi/10.1002/glia.23869
  61. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202000678R
  62. Jan 2020
  63. jcb.rupress.org jcb.rupress.org
    A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor
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    jcb.rupress.org/content/218/2/644
  64. jem.rupress.org jem.rupress.org
    Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis
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    jem.rupress.org/content/216/2/350
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight
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    ncbi.nlm.nih.gov/pmc/articles/PMC6391466/
  66. Nov 2018
  67. www.sciencedirect.com www.sciencedirect.com
    Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression
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    sciencedirect.com/science/article/pii/S0896627318306834
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC5752207/
  69. europepmc.org europepmc.org
    Untitled document
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    europepmc.org/articles/PMC5752207/
  70. Nov 2017
  71. www.sciencedirect.com www.sciencedirect.com
    Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers
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    sciencedirect.com/science/article/pii/S1934590916302661