Hypothesis

34 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

Polyserine-mediated targeting of FAF2/UBXD8 ameliorates tau aggregation

1
1. scibot 03 Sep 2025
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.neuron.2025.08.002
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627325005872
www.sciencedirect.com www.sciencedirect.com

Biomarker-related phospho-tau217 appears in synapses around Aβ plaques prior to tau tangle in cerebral cortex of preclinical Alzheimer’s disease

1
1. scibot 03 Sep 2025
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2025.116203
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472500974X
May 2025
www.sciencedirect.com www.sciencedirect.com

Cell-death pathways and tau-associated neuronal vulnerability in Alzheimer’s disease

1
1. scibot 31 May 2025
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2025.115758
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725005297
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation

1
1. scibot 21 May 2025
  
  in Public
  
  AB_223649
  
  DOI: 10.1186/s40478-025-02000-4
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids

1
1. scibot 06 Mar 2025
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.neuron.2025.02.001
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S089662732500114X
Jan 2025
elifesciences.org elifesciences.org

SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

1
1. scibot 14 Jan 2025
  
  in Public
  
  Thermo Fisher Scientific #MN1040
  
  DOI: 10.7554/eLife.98152.2
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @inessasarian
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

elifesciences.org/reviewed-preprints/98152
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

1
1. scibot 09 Apr 2024
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.cell.2024.03.015
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424003064
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Characterization of Traumatic Brain Injury in a Gyrencephalic Ferret Model Using the Novel Closed Head Injury Model of Engineered Rotational Acceleration (CHIMERA)

1
1. scibot 01 Dec 2023
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1089/neur.2023.0047
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10659026/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease

1
1. scibot 17 Nov 2023
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2023.113436
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014481
Jun 2023
www.biorxiv.org www.biorxiv.org

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

1
1. scibot 23 Jun 2023
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1101/2023.06.12.543777
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

biorxiv.org/content/10.1101/2023.06.12.543777v1
Nov 2022
www.sciencedirect.com www.sciencedirect.com

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

1
1. scibot 11 Nov 2022
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.neuron.2022.10.022
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627322009552
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Ethanol sustains phosphorylated tau protein in the cultured neonatal rat hippocampus: Implications for fetal alcohol spectrum disorders

1
1. scibot 16 Aug 2022
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.alcohol.2022.07.007
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0741832922000696
alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com

Phosphorylated tau sites that are elevated in Alzheimer's disease fluid biomarkers are visualized in early neurofibrillary tangle maturity levels in the post mortem brain

1
1. scibot 04 Aug 2022
  
  in Public
  
  AB_223649
  
  DOI: 10.1002/alz.12749
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12749
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

1
1. scibot 22 Sep 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2021.109720
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721011694
www.sciencedirect.com www.sciencedirect.com

Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau

1
1. scibot 01 Sep 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2021.109638
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721010810
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 11 Aug 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1523/JNEUROSCI.1230-17.2017
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5700423/
content.iospress.com content.iospress.com

Untitled document

1
1. scibot 09 Aug 2021
  
  in Public
  
  AB_223649
  
  DOI: 10.3233/JAD-180556
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

content.iospress.com/articles/journal-of-alzheimers-disease/jad180556
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1523/JNEUROSCI.1550-17.2017
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.neuron.2016.12.023
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5363269/
www.sciencedirect.com www.sciencedirect.com

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.neuron.2018.10.014
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627318309024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment

2
1. scibot 27 Jul 2021
  
  in Public
  
  AB_223649
  
  DOI: 10.1002/cne.23877
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @gabimpine
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRIDCUR:Validated RRIDCUR:Duplicate RRID:AB_223649
2. scibot 27 Jul 2021
  
  in Public
  
  AB_223649
  
  DOI: 10.1002/cne.23877
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @gabimpine
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

RRIDCUR:Duplicate

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/cne.23877/full
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature

1
1. scibot 02 Jul 2021
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1186/s40478-021-01220-8
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC8243463/
May 2021
www.sciencedirect.com www.sciencedirect.com

Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model

1
1. scibot 09 May 2021
  
  in Public
  
  AB_223649
  
  DOI: 10.1016/j.phymed.2020.153324
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0944711320301562
Oct 2020
link.springer.com link.springer.com

Plasma Leptin Reflects Progression of Neurofibrillary Pathology in Animal Model of Tauopathy

1
1. scibot 02 Oct 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1007/s10571-020-00972-6
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

link.springer.com/article/10.1007/s10571-020-00972-6
Sep 2020
www.jneurosci.org www.jneurosci.org

Activated CX3CL1/Smad2 signals prevent neuronal loss and Alzheimer's tau pathology-mediated cognitive dysfunction

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1523/JNEUROSCI.1333-19.2019
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

jneurosci.org/content/40/5/1133
www.sciencedirect.com www.sciencedirect.com

Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.cmet.2020.02.004
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_223649
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413120300632
www.sciencedirect.com www.sciencedirect.com

Fyn Kinase Controls Tau Aggregation In Vivo

1
1. scibot 14 Sep 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2020.108045
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720310305
Jan 2020
www.jneurosci.org www.jneurosci.org

Activity-dependent reconnection of adult-born dentate granule cells in a mouse model of frontotemporal dementia

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1523/JNEUROSCI.2724-18.2019
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

jneurosci.org/content/39/29/5794
onlinelibrary.wiley.com onlinelibrary.wiley.com

High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1111/jnc.14830
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/jnc.14830
journals.plos.org journals.plos.org

Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1371/journal.pone.0223509
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

journals.plos.org/plosone/article
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_223649
  
  DOI: 10.1016/j.celrep.2019.01.023
  
  Resource: (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_223649
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719300324
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_223649
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  SciCrunch record: RRID:AB_223649
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_223649
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (Thermo Fisher Scientific Cat# MN1040, RRID:AB_223649)
  
  SciCrunch record: RRID:AB_223649
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_223649 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_223649

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627316309965